Detailed information NTG0909489

Bioinformatically predicted

Overview

• Name: micB
• Type: Regulator
• Locus tag: SM121_RS05030
• Genome accession: NZ_CP139418
• Coordinates: 1028424..1029776 (+)
• Length: 450 a.a.
• NCBI ID: WP_003005638.1
• Uniprot ID: A0AB39LAM2
• Organism: Streptococcus dentalis strain S1
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1023424..1034776

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SM121_RS05015 (SM121_05015)	thrS	1024024..1025967 (+)	1944	WP_320910524.1	threonine--tRNA ligase	-
SM121_RS05020 (SM121_05020)	-	1026179..1027228 (-)	1050	WP_320910525.1	DUF389 domain-containing protein	-
SM121_RS05025 (SM121_05025)	micA	1027730..1028431 (+)	702	WP_003005102.1	response regulator YycF	Regulator
SM121_RS05030 (SM121_05030)	micB	1028424..1029776 (+)	1353	WP_003005638.1	cell wall metabolism sensor histidine kinase VicK	Regulator
SM121_RS05035 (SM121_05035)	vicX	1029784..1030593 (+)	810	WP_320910526.1	MBL fold metallo-hydrolase	Regulator
SM121_RS05040 (SM121_05040)	-	1030713..1031099 (+)	387	WP_320910527.1	YbaN family protein	-
SM121_RS05045 (SM121_05045)	-	1031351..1031812 (-)	462	WP_320910528.1	hypothetical protein	-
SM121_RS05050 (SM121_05050)	rnc	1032146..1032847 (+)	702	WP_320910529.1	ribonuclease III	-

Sequence

Protein

• Length: 450 a.a.
• Molecular weight: 51143.32 Da
• Isoelectric Point: 4.5621

>NTDB_id=909489 SM121_RS05030 WP_003005638.1 1028424..1029776(+) (micB) [Streptococcus dentalis strain S1]
MIDQLKQFVMSSNFVFVLITVGFIIVVALLLLENRRDNIKLRQLNAKIKDLIAGDYSEVVDMQGSPELTDMTNSINDLSE
VIRLTHENLEQETKRLTSILSYMTDGVLATNRRGQIIMVNEMAAKQLNVNPDEVLNTSILDLLSLGDDYDLRSLITEVPE
LTIDSQDENGEYLSLRVRFALIRRESGFISGLVAVLHDTTEQDKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALS
EPVAPDFVKVSLNETNRMMRMVTDLLSLSRIDNETSQLDIELTNFTAFITFILNRFDKIKSQSQEDTKKYELIREYPITP
IWVEIDTDKMTQVIDNILNNAIKYSPDGGKIKVGMRTTDAQLIISISDEGLGIPKKDLPRIFDRFYRVDKARSRAQGGTG
LGLAIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDKDAIKDDWDTEEEE

Nucleotide

• Length: 1353 bp

>NTDB_id=909489 SM121_RS05030 WP_003005638.1 1028424..1029776(+) (micB) [Streptococcus dentalis strain S1]
ATGATTGATCAACTAAAACAATTTGTCATGTCGTCGAACTTTGTCTTTGTGCTGATTACGGTTGGGTTTATCATTGTGGT
TGCCTTGCTTTTGCTGGAAAACCGTAGGGACAATATCAAGCTCAGACAATTAAACGCTAAAATTAAGGATCTGATTGCAG
GGGATTATTCCGAAGTGGTCGATATGCAAGGAAGTCCAGAACTGACGGATATGACCAATAGTATCAATGATCTGTCTGAA
GTTATTCGCCTGACGCATGAAAACTTGGAACAAGAAACCAAGCGTTTGACCAGTATTCTTTCTTACATGACAGATGGGGT
ACTTGCGACCAACAGACGTGGTCAGATCATCATGGTCAATGAAATGGCAGCCAAGCAATTGAACGTTAATCCAGATGAGG
TGCTCAATACCAGTATTCTGGATTTGCTTTCGCTTGGAGATGACTATGATTTGCGAAGCTTGATTACAGAAGTACCAGAG
TTGACCATTGATTCCCAGGATGAAAATGGGGAATACTTAAGTCTTCGTGTGCGCTTTGCCTTGATTCGTCGCGAGTCAGG
TTTTATCTCTGGTCTGGTAGCTGTCTTGCACGATACGACAGAGCAGGACAAGGAAGAGCGGGAACGTCGCCTCTTCGTCT
CCAATGTGAGTCATGAATTACGGACACCTTTGACCAGTGTGAAATCCTATCTGGAAGCCCTAGACGATGGCGCTTTGTCA
GAGCCAGTAGCACCAGATTTTGTCAAGGTTTCACTCAATGAAACCAACCGCATGATGCGTATGGTCACAGATCTATTGAG
CTTGTCACGAATTGATAATGAAACCAGTCAGTTGGACATCGAGTTGACCAACTTTACGGCCTTTATCACCTTTATTTTAA
ACCGATTTGATAAGATCAAGAGTCAATCGCAAGAAGATACCAAGAAGTATGAACTGATCCGGGAATACCCGATCACACCG
ATCTGGGTTGAAATTGATACGGATAAAATGACCCAGGTGATCGACAATATCTTGAACAATGCCATCAAGTACTCACCTGA
TGGTGGAAAGATTAAGGTAGGGATGAGAACAACTGATGCCCAGTTGATTATCTCCATCTCAGATGAGGGCTTGGGAATTC
CCAAGAAAGACTTGCCTCGCATTTTTGATCGCTTTTACCGAGTGGATAAGGCGCGTAGCCGGGCCCAAGGTGGGACTGGT
CTAGGCCTAGCCATTGCTAAGGAGATCATTAAGCAACACAAAGGCTTTATTTGGGCCAAGAGTGAATATGGCAAGGGATC
TACCTTTACCATTGTCTTGCCGTACGACAAAGACGCTATTAAAGACGACTGGGATACAGAAGAGGAAGAATAA

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (326-436)

• PAS fold (PAS) (96-198)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
micB	Streptococcus pneumoniae Cp1015	78.912	98	0.773
vicK	Streptococcus mutans UA159	71.007	90.444	0.642