NTDB

Overview

Name	comEA/celA/cilE	Type	Machinery gene
Locus tag	SOL79_RS09175	Genome accession	NZ_CP139210
Coordinates	2090616..2091254 (+)	Length	212 a.a.
NCBI ID	WP_135027227.1	Uniprot ID	-
Organism	Streptococcus sp. VEG1o
Function	dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 2085616..2096254

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SOL79_RS09140 (SOL79_09125)	-	2085951..2086229 (+)	279	WP_135027236.1	autorepressor SdpR family transcription factor	-
SOL79_RS09145 (SOL79_09130)	-	2086216..2086818 (+)	603	WP_135027234.1	DUF1648 domain-containing protein	-
SOL79_RS09150 (SOL79_09135)	-	2087213..2087728 (+)	516	WP_135027232.1	isoprenylcysteine carboxyl methyltransferase family protein	-
SOL79_RS09155 (SOL79_09140)	-	2088174..2088581 (+)	408	WP_135027377.1	GNAT family N-acetyltransferase	-
SOL79_RS09160 (SOL79_09145)	-	2088695..2088952 (-)	258	WP_135027375.1	GIY-YIG nuclease family protein	-
SOL79_RS09165 (SOL79_09150)	-	2088960..2089709 (-)	750	WP_135027230.1	tRNA1(Val) (adenine(37)-N6)-methyltransferase	-
SOL79_RS09170 (SOL79_09155)	-	2089805..2090551 (+)	747	WP_135027229.1	lysophospholipid acyltransferase family protein	-
SOL79_RS09175 (SOL79_09160)	comEA/celA/cilE	2090616..2091254 (+)	639	WP_135027227.1	helix-hairpin-helix domain-containing protein	Machinery gene
SOL79_RS09180 (SOL79_09165)	comEC/celB	2091238..2093475 (+)	2238	WP_135027225.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
SOL79_RS09185 (SOL79_09170)	-	2094180..2095703 (+)	1524	WP_135027223.1	AMP-binding protein	-

Sequence

Protein

Download Length: 212 a.a. Molecular weight: 22754.04 Da Isoelectric Point: 5.3424

                                >NTDB_id=908033 SOL79_RS09175 WP_135027227.1 2090616..2091254(+) (comEA/celA/cilE) [Streptococcus sp. VEG1o]

MSEKWIPFLRHYQLLVVVAVGGLVMTVTFFLIAPIRPSGELGRVEELVSSSEQVMEMPISKQSIESLMVDVKGAVKKPGI

YHLSVGSRVHDAVEAAGGLTEAADSKSINLAQKLSDEGVIYVATKEEAISVVPTTRTAQTSSDKGVKEGLVNLNTATEAD

LQTIAGIGTKRATDIIAYRESKGHFQSVDDLKDVPGIGSKSLENIRPYVTVD

Nucleotide

Download Length: 639 bp

                                >NTDB_id=908033 SOL79_RS09175 WP_135027227.1 2090616..2091254(+) (comEA/celA/cilE) [Streptococcus sp. VEG1o]

ATGTCTGAAAAATGGATACCATTTTTGCGTCACTATCAATTATTGGTTGTGGTAGCTGTAGGGGGGCTTGTGATGACTGT

GACTTTCTTTTTGATAGCTCCAATAAGACCGAGTGGGGAGCTGGGTCGCGTGGAAGAATTAGTAAGTAGCAGCGAACAGG

TAATGGAGATGCCAATTAGTAAGCAGTCCATAGAGAGCCTAATGGTTGATGTCAAAGGCGCAGTCAAGAAACCAGGAATT

TATCATTTGTCAGTAGGTAGTCGTGTTCATGATGCGGTGGAAGCAGCGGGTGGTTTGACAGAGGCTGCTGATTCTAAATC

CATCAATTTAGCTCAGAAGCTGAGTGATGAGGGGGTTATTTACGTAGCAACCAAGGAGGAAGCAATCTCTGTTGTACCTA

CTACAAGGACAGCACAAACAAGTAGCGATAAGGGAGTAAAGGAGGGGCTAGTGAATCTCAATACTGCAACAGAGGCAGAT

TTGCAGACCATTGCAGGTATCGGTACTAAGCGTGCGACAGATATTATTGCCTATCGTGAGAGCAAGGGGCATTTTCAATC

GGTTGATGATTTGAAAGATGTACCTGGAATTGGTAGTAAGAGTCTGGAGAACATTCGTCCTTATGTCACAGTTGATTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(68-121)

Helix-hairpin-helix motif (HHH_3)

(146-210)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comEA/celA/cilE	Streptococcus mitis NCTC 12261	47.085	100	0.495
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	47.727	100	0.495
comEA/celA/cilE	Streptococcus pneumoniae Rx1	46.637	100	0.491
comEA/celA/cilE	Streptococcus pneumoniae D39	46.637	100	0.491
comEA/celA/cilE	Streptococcus pneumoniae R6	46.637	100	0.491
comEA/celA/cilE	Streptococcus mitis SK321	46.119	100	0.476
comEA	Streptococcus thermophilus LMD-9	60.403	70.283	0.425
comEA	Lactococcus lactis subsp. cremoris KW2	36.818	100	0.382

Detailed information NTG0908033