NTDB

Overview

Name	clpP	Type	Regulator
Locus tag	SA286_RS16405	Genome accession	NZ_CP137888
Coordinates	3164965..3165561 (+)	Length	198 a.a.
NCBI ID	WP_024719872.1	Uniprot ID	A0A2G8ISB7
Organism	Bacillus altitudinis strain ECC22
Function	degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3159965..3170561

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
SA286_RS16385 (SA286_16385)	-	3160344..3161513 (-)	1170	WP_045034009.1	macrolide family glycosyltransferase	-
SA286_RS16390 (SA286_16390)	-	3161680..3162570 (-)	891	WP_045034067.1	ABC transporter substrate-binding protein	-
SA286_RS16395 (SA286_16395)	-	3162811..3164517 (+)	1707	WP_324657586.1	alginate lyase family protein	-
SA286_RS16405 (SA286_16405)	clpP	3164965..3165561 (+)	597	WP_024719872.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
SA286_RS16410 (SA286_16410)	-	3165617..3166195 (-)	579	WP_024719873.1	TIGR00730 family Rossman fold protein	-
SA286_RS16415 (SA286_16415)	-	3166332..3166673 (+)	342	WP_017368102.1	MazG nucleotide pyrophosphohydrolase domain-containing protein	-
SA286_RS16420 (SA286_16420)	-	3166703..3168325 (-)	1623	WP_061420267.1	SulP family inorganic anion transporter	-
SA286_RS16425 (SA286_16425)	-	3168363..3168944 (-)	582	WP_017357909.1	beta-class carbonic anhydrase	-
SA286_RS16430 (SA286_16430)	-	3169508..3170485 (+)	978	WP_061420932.1	2-hydroxyacid dehydrogenase	-

Sequence

Protein

Download Length: 198 a.a. Molecular weight: 21832.00 Da Isoelectric Point: 4.6905

                                >NTDB_id=901057 SA286_RS16405 WP_024719872.1 3164965..3165561(+) (clpP) [Bacillus altitudinis strain ECC22]

MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLEAEDPEKDISIYINSPGGSITAGMAIYDT

MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILSLRDKLNQVLAERTGQ

PIEVIERDTDRDNFKTAEEALQYGLIDKVLTRNSEEQK

Nucleotide

Download Length: 597 bp

                                >NTDB_id=901057 SA286_RS16405 WP_024719872.1 3164965..3165561(+) (clpP) [Bacillus altitudinis strain ECC22]

ATGAATTTAATACCTACAGTCATTGAGCAAACAAATCGTGGGGAAAGAGCTTACGACATTTATTCTCGTCTTTTAAAAGA

CCGTATTATCATGCTTGGTTCTGCGATCGATGACAATGTTGCCAACTCCATCGTATCACAGCTTCTTTTCTTAGAAGCCG

AGGATCCAGAAAAAGATATCTCTATCTACATTAACAGCCCTGGCGGTTCGATCACAGCTGGTATGGCCATTTACGATACG

ATGCAATTTATTAAACCAAAGGTATCAACTATTTGTATTGGTATGGCTGCATCTATGGGTGCGTTCCTGCTTGCTGCTGG

TGAAAAAGGTAAGCGTTATGCCCTTCCAAATAGTGAAGTGATGATTCACCAACCACTAGGTGGTGCGCAAGGTCAAGCAA

CAGAAATTGAAATTGCGGCAAAACGAATCCTTTCTTTACGCGATAAACTGAACCAAGTACTTGCTGAACGTACTGGTCAG

CCAATTGAAGTCATTGAGCGCGATACAGATCGTGACAACTTCAAAACAGCGGAAGAAGCACTTCAATACGGACTCATTGA

CAAAGTCTTGACCCGTAATTCAGAAGAACAAAAATAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(13-192)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A2G8ISB7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
clpP	Bacillus subtilis subsp. subtilis str. 168	92.929	100	0.929
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	67.539	96.465	0.652
clpP	Streptococcus thermophilus LMG 18311	58.549	97.475	0.571
clpP	Streptococcus thermophilus LMD-9	58.549	97.475	0.571
clpP	Lactococcus lactis subsp. cremoris KW2	56.701	97.98	0.556
clpP	Streptococcus pneumoniae Rx1	56.186	97.98	0.551
clpP	Streptococcus pneumoniae D39	56.186	97.98	0.551
clpP	Streptococcus pneumoniae R6	56.186	97.98	0.551
clpP	Streptococcus pneumoniae TIGR4	56.186	97.98	0.551
clpP	Streptococcus pyogenes JRS4	55.44	97.475	0.54
clpP	Streptococcus pyogenes MGAS315	55.44	97.475	0.54
clpP	Streptococcus mutans UA159	54.639	97.98	0.535
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	54.639	97.98	0.535

Detailed information NTG0901057