Detailed information NTG0896291

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: R4705_RS08750
• Genome accession: NZ_CP137115
• Coordinates: 1673124..1673714 (+)
• Length: 196 a.a.
• NCBI ID: WP_000613477.1
• Uniprot ID: A0A064BX72
• Organism: Streptococcus pneumoniae strain 20614-6
• Function: degradation of ComX; degradation of ComW (predicted from homology) Competence regulation

Genomic Context

Location: 1668124..1678714

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4705_RS08720	-	1668510..1668965 (-)	456	WP_001823744.1	8-oxo-dGTP diphosphatase	-
R4705_RS08725	-	1668985..1670160 (-)	1176	WP_000680057.1	NAD(P)/FAD-dependent oxidoreductase	-
R4705_RS08730	-	1670219..1671064 (-)	846	WP_000219939.1	DegV family protein	-
R4705_RS08735	-	1671189..1671746 (+)	558	WP_000004139.1	TetR/AcrR family transcriptional regulator	-
R4705_RS08740	-	1671765..1672232 (+)	468	WP_000136976.1	cytidine/deoxycytidylate deaminase family protein	-
R4705_RS08745	upp	1672321..1672950 (+)	630	WP_000515972.1	uracil phosphoribosyltransferase	-
R4705_RS08750	clpP	1673124..1673714 (+)	591	WP_000613477.1	ATP-dependent Clp protease proteolytic subunit ClpP	Regulator
R4705_RS08755	-	1673793..1674041 (+)	249	WP_000462126.1	YlbG family protein	-
R4705_RS08760	-	1674143..1675303 (+)	1161	WP_000726140.1	ABC transporter substrate-binding protein	-
R4705_RS08765	-	1675571..1676440 (+)	870	WP_000941421.1	branched-chain amino acid ABC transporter permease	-
R4705_RS08770	-	1676444..1677400 (+)	957	WP_000662293.1	branched-chain amino acid ABC transporter permease	-
R4705_RS08775	-	1677400..1678164 (+)	765	WP_001186003.1	ABC transporter ATP-binding protein	-

Sequence

Protein

• Length: 196 a.a.
• Molecular weight: 21358.36 Da
• Isoelectric Point: 4.4910

>NTDB_id=896291 R4705_RS08750 WP_000613477.1 1673124..1673714(+) (clpP) [Streptococcus pneumoniae strain 20614-6]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
SMEKVHADAERDNWMSAQETLEYGFIDEIMANNSLN

Nucleotide

• Length: 591 bp

>NTDB_id=896291 R4705_RS08750 WP_000613477.1 1673124..1673714(+) (clpP) [Streptococcus pneumoniae strain 20614-6]
ATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCTTACGATATTTACTCACGTCTTCTCAAAGACCGCAT
CATTATGCTGACAGGTCCGGTTGAAGACAATATGGCTAACTCTGTTATTGCCCAATTGCTTTTCTTGGATGCCCAAGATA
GTACAAAAGATATTTACCTTTATGTCAATACACCAGGTGGTTCTGTTTCAGCTGGTTTGGCAATCGTAGATACCATGAAC
TTTATCAAGGCAGATGTCCAAACCATTGTTATGGGAATGGCTGCATCTATGGGAACAGTCATCGCATCAAGTGGAGCAAA
AGGCAAACGTTTCATGCTTCCAAATGCTGAATACATGATTCACCAACCAATGGGCGGTACAGGTGGTGGTACCCAACAAA
CTGATATGGCTATCGCTGCAGAACACTTGCTCAAAACTCGTAATACCTTGGAAAAAATCTTGGCTGAAAATTCAGGTCAG
TCAATGGAAAAAGTCCATGCAGATGCAGAACGTGATAACTGGATGAGCGCCCAGGAAACACTTGAATATGGCTTTATTGA
TGAAATTATGGCCAACAATTCATTGAACTAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (11-192)

3D structure

• AlphaFold DB: A0A064BX72

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Streptococcus pneumoniae Rx1	100	100	1
clpP	Streptococcus pneumoniae D39	100	100	1
clpP	Streptococcus pneumoniae R6	100	100	1
clpP	Streptococcus pneumoniae TIGR4	100	100	1
clpP	Streptococcus thermophilus LMG 18311	92.821	99.49	0.923
clpP	Streptococcus thermophilus LMD-9	92.821	99.49	0.923
clpP	Streptococcus pyogenes JRS4	90.769	99.49	0.903
clpP	Streptococcus pyogenes MGAS315	90.769	99.49	0.903
clpP	Streptococcus mutans UA159	85.714	100	0.857
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	85.128	99.49	0.847
clpP	Lactococcus lactis subsp. cremoris KW2	84.615	99.49	0.842
clpP	Bacillus subtilis subsp. subtilis str. 168	58.854	97.959	0.577
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	58.031	98.469	0.571