Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   R4707_RS09485 Genome accession   NZ_CP137113
Coordinates   1802077..1802667 (+) Length   196 a.a.
NCBI ID   WP_081543082.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain ZGX     
Function   degradation of ComX; degradation of ComW (predicted from homology)   
Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1800718..1811623 1802077..1802667 within 0


Gene organization within MGE regions


Location: 1800718..1811623
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4707_RS09475 - 1800718..1801185 (+) 468 WP_000136976.1 cytidine/deoxycytidylate deaminase family protein -
  R4707_RS09480 upp 1801274..1801903 (+) 630 WP_000515972.1 uracil phosphoribosyltransferase -
  R4707_RS09485 clpP 1802077..1802667 (+) 591 WP_081543082.1 ATP-dependent Clp protease proteolytic subunit ClpP Regulator
  R4707_RS09490 - 1802746..1802994 (+) 249 WP_000462126.1 YlbG family protein -
  R4707_RS09495 - 1803096..1804256 (+) 1161 WP_000726141.1 ABC transporter substrate-binding protein -
  R4707_RS09500 - 1804524..1805393 (+) 870 WP_000941426.1 branched-chain amino acid ABC transporter permease -
  R4707_RS09505 - 1805397..1806353 (+) 957 WP_000662293.1 branched-chain amino acid ABC transporter permease -
  R4707_RS09510 - 1806353..1807117 (+) 765 WP_001186003.1 ABC transporter ATP-binding protein -
  R4707_RS09515 - 1807117..1807827 (+) 711 WP_000062219.1 ABC transporter ATP-binding protein -
  R4707_RS09520 - 1808135..1808791 (+) 657 WP_000268677.1 CBS domain-containing protein -
  R4707_RS09525 prfB 1808899..1809994 (+) 1096 WP_010963246.1 peptide chain release factor 2 -
  R4707_RS09530 ftsE 1810012..1810704 (+) 693 WP_000022265.1 cell division ATP-binding protein FtsE -
  R4707_RS09535 ftsX 1810697..1811623 (+) 927 WP_081543084.1 permease-like cell division protein FtsX -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 21328.37 Da        Isoelectric Point: 4.5654

>NTDB_id=896136 R4707_RS09485 WP_081543082.1 1802077..1802667(+) (clpP) [Streptococcus pneumoniae strain ZGX]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMLTGPVEDNMANSVIAQLLFLDAQDSTKDIYLYVNTPGGSVSAGLAIVDTMN
FIKADVQTIVMGMAASMGTVIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNTLEKILAENSGQ
SMEKVHADAERDNWMSAQVTLEYGFIDEIMANNSLN

Nucleotide


Download         Length: 591 bp        

>NTDB_id=896136 R4707_RS09485 WP_081543082.1 1802077..1802667(+) (clpP) [Streptococcus pneumoniae strain ZGX]
ATGATTCCTGTAGTTATTGAACAAACAAGCCGTGGAGAACGTTCTTACGATATTTACTCACGTCTTCTCAAAGACCGCAT
CATTATGCTGACAGGTCCGGTTGAAGACAATATGGCTAACTCTGTTATTGCCCAATTGCTTTTCTTGGATGCCCAAGATA
GTACAAAAGATATTTACCTTTATGTCAATACACCAGGTGGTTCTGTTTCAGCTGGTTTGGCAATCGTAGATACCATGAAC
TTTATCAAGGCAGATGTCCAAACCATTGTTATGGGAATGGCTGCATCTATGGGAACAGTCATCGCATCAAGTGGAGCAAA
AGGCAAACGTTTCATGCTTCCAAATGCTGAATACATGATTCACCAACCAATGGGCGGTACAGGTGGTGGTACCCAACAAA
CTGATATGGCTATCGCTGCAGAACACTTGCTCAAAACTCGTAATACCTTGGAAAAAATCTTGGCTGAAAATTCAGGTCAG
TCAATGGAAAAAGTCCATGCAGATGCAGAACGTGATAACTGGATGAGCGCCCAGGTAACACTTGAATATGGCTTTATTGA
TGAAATTATGGCCAACAATTCATTGAACTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(11-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Streptococcus pneumoniae Rx1

99.49

100

0.995
  clpP Streptococcus pneumoniae D39

99.49

100

0.995
  clpP Streptococcus pneumoniae R6

99.49

100

0.995
  clpP Streptococcus pneumoniae TIGR4

99.49

100

0.995
  clpP Streptococcus thermophilus LMG 18311

92.308

99.49

0.918
  clpP Streptococcus thermophilus LMD-9

92.308

99.49

0.918
  clpP Streptococcus pyogenes JRS4

90.256

99.49

0.898
  clpP Streptococcus pyogenes MGAS315

90.256

99.49

0.898
  clpP Streptococcus mutans UA159

85.204

100

0.852
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

84.615

99.49

0.842
  clpP Lactococcus lactis subsp. cremoris KW2

84.103

99.49

0.837
  clpP Bacillus subtilis subsp. subtilis str. 168

58.333

97.959

0.571
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

57.513

98.469

0.566