Detailed information    

insolico Bioinformatically predicted

Overview

Name   comGE/cglE   Type   Machinery gene
Locus tag   R4706_RS06340 Genome accession   NZ_CP137111
Coordinates   1264005..1264307 (+) Length   100 a.a.
NCBI ID   WP_257890291.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 17023     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1259005..1269307
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4706_RS06310 - 1259762..1260820 (+) 1059 WP_044727686.1 zinc-dependent alcohol dehydrogenase family protein -
  R4706_RS06315 - 1260971..1261336 (+) 366 WP_000286415.1 DUF1033 family protein -
  R4706_RS06320 comGA/cglA/cilD 1261412..1262353 (+) 942 WP_317815369.1 competence type IV pilus ATPase ComGA Machinery gene
  R4706_RS06325 comGB/cglB 1262301..1263317 (+) 1017 WP_078102664.1 competence type IV pilus assembly protein ComGB Machinery gene
  R4706_RS06330 comGC/cglC 1263319..1263645 (+) 327 WP_000738627.1 comG operon protein ComGC Machinery gene
  R4706_RS06335 comGD/cglD 1263638..1264042 (+) 405 WP_000588018.1 competence type IV pilus minor pilin ComGD Machinery gene
  R4706_RS06340 comGE/cglE 1264005..1264307 (+) 303 WP_257890291.1 competence type IV pilus minor pilin ComGE Machinery gene
  R4706_RS06345 comGF/cglF 1264270..1264731 (+) 462 WP_044727689.1 competence type IV pilus minor pilin ComGF Machinery gene
  R4706_RS06350 comGG/cglG 1264709..1265122 (+) 414 WP_000265624.1 competence type IV pilus minor pilin ComGG Machinery gene
  R4706_RS06355 - 1265259..1265853 (+) 595 Protein_1240 class I SAM-dependent methyltransferase -
  R4706_RS06360 comYH 1265914..1266867 (+) 954 WP_044727690.1 class I SAM-dependent methyltransferase Machinery gene
  R4706_RS06365 - 1266918..1268108 (+) 1191 WP_000167765.1 acetate kinase -
  R4706_RS06370 - 1268109..1268240 (+) 132 WP_000768904.1 hypothetical protein -
  R4706_RS06375 rnpA 1268257..1268628 (+) 372 WP_000739246.1 ribonuclease P protein component -

Sequence

Protein


Download         Length: 100 a.a.        Molecular weight: 11066.99 Da        Isoelectric Point: 8.6013

>NTDB_id=895957 R4706_RS06340 WP_257890291.1 1264005..1264307(+) (comGE/cglE) [Streptococcus pneumoniae strain 17023]
MEKLNALRKQKIRAVILLEAVVALAIFASIATLLLGQIQKNRQEEAKILQKEEVLRVANMALQTGQSQVSINGVEIQVFS
SEKGLEVYHGSEQLLAIKEP

Nucleotide


Download         Length: 303 bp        

>NTDB_id=895957 R4706_RS06340 WP_257890291.1 1264005..1264307(+) (comGE/cglE) [Streptococcus pneumoniae strain 17023]
ATGGAAAAATTAAACGCATTAAGGAAACAAAAAATTAGGGCAGTGATTTTACTGGAAGCAGTAGTCGCTCTAGCTATCTT
TGCCAGCATTGCGACCCTCCTTTTGGGACAAATTCAAAAAAATAGGCAAGAGGAAGCAAAAATCTTGCAAAAGGAAGAAG
TCTTGAGGGTAGCTAACATGGCCTTGCAGACGGGGCAAAGTCAGGTAAGCATCAACGGAGTTGAGATTCAGGTATTTTCT
AGTGAAAAAGGATTGGAGGTCTACCATGGTTCAGAACAGTTGTTGGCAATCAAAGAGCCATAA

Domains

Predicted by InterproScan.

Type II secretory pathway pseudopilin (ComGE)

(16-97)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comGE/cglE Streptococcus pneumoniae Rx1

98

100

0.98
  comGE/cglE Streptococcus pneumoniae D39

98

100

0.98
  comGE/cglE Streptococcus pneumoniae R6

98

100

0.98
  comGE/cglE Streptococcus pneumoniae TIGR4

98

100

0.98
  comGE/cglE Streptococcus mitis NCTC 12261

96

100

0.96
  comGE/cglE Streptococcus mitis SK321

96

100

0.96
  comYE Streptococcus mutans UA140

44.444

90

0.4
  comYE Streptococcus mutans UA159

44.444

90

0.4