Detailed information NTG0895955

Bioinformatically predicted

Overview

• Name: comGC/cglC
• Type: Machinery gene
• Locus tag: R4706_RS06330
• Genome accession: NZ_CP137111
• Coordinates: 1263319..1263645 (+)
• Length: 108 a.a.
• NCBI ID: WP_000738627.1
• Uniprot ID: A0A0H2URU9
• Organism: Streptococcus pneumoniae strain 17023
• Function: dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1258319..1268645

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4706_RS06305	nagA	1258452..1259603 (+)	1152	WP_044727685.1	N-acetylglucosamine-6-phosphate deacetylase	-
R4706_RS06310	-	1259762..1260820 (+)	1059	WP_044727686.1	zinc-dependent alcohol dehydrogenase family protein	-
R4706_RS06315	-	1260971..1261336 (+)	366	WP_000286415.1	DUF1033 family protein	-
R4706_RS06320	comGA/cglA/cilD	1261412..1262353 (+)	942	WP_317815369.1	competence type IV pilus ATPase ComGA	Machinery gene
R4706_RS06325	comGB/cglB	1262301..1263317 (+)	1017	WP_078102664.1	competence type IV pilus assembly protein ComGB	Machinery gene
R4706_RS06330	comGC/cglC	1263319..1263645 (+)	327	WP_000738627.1	comG operon protein ComGC	Machinery gene
R4706_RS06335	comGD/cglD	1263638..1264042 (+)	405	WP_000588018.1	competence type IV pilus minor pilin ComGD	Machinery gene
R4706_RS06340	comGE/cglE	1264005..1264307 (+)	303	WP_257890291.1	competence type IV pilus minor pilin ComGE	Machinery gene
R4706_RS06345	comGF/cglF	1264270..1264731 (+)	462	WP_044727689.1	competence type IV pilus minor pilin ComGF	Machinery gene
R4706_RS06350	comGG/cglG	1264709..1265122 (+)	414	WP_000265624.1	competence type IV pilus minor pilin ComGG	Machinery gene
R4706_RS06355	-	1265259..1265853 (+)	595	Protein_1240	class I SAM-dependent methyltransferase	-
R4706_RS06360	comYH	1265914..1266867 (+)	954	WP_044727690.1	class I SAM-dependent methyltransferase	Machinery gene
R4706_RS06365	-	1266918..1268108 (+)	1191	WP_000167765.1	acetate kinase	-
R4706_RS06370	-	1268109..1268240 (+)	132	WP_000768904.1	hypothetical protein	-
R4706_RS06375	rnpA	1268257..1268628 (+)	372	WP_000739246.1	ribonuclease P protein component	-

Sequence

Protein

• Length: 108 a.a.
• Molecular weight: 12177.34 Da
• Isoelectric Point: 10.1876

>NTDB_id=895955 R4706_RS06330 WP_000738627.1 1263319..1263645(+) (comGC/cglC) [Streptococcus pneumoniae strain 17023]
MKKMMTFLKKAKVKAFTLVEMLVVLLIISVLFLLFVPNLTKQKEAVNDKGKAAVVKVVESQAELYSLEKNEDASLRKLQA
DGRITEEQAKAYKEYNDKNGGANRKVND

Nucleotide

• Length: 327 bp

>NTDB_id=895955 R4706_RS06330 WP_000738627.1 1263319..1263645(+) (comGC/cglC) [Streptococcus pneumoniae strain 17023]
ATGAAAAAAATGATGACATTCTTGAAAAAAGCTAAGGTTAAAGCTTTTACATTGGTGGAAATGTTGGTGGTCTTGCTGAT
TATCAGCGTGCTTTTCTTGCTCTTTGTACCTAATCTGACCAAGCAAAAAGAAGCAGTCAATGACAAAGGAAAAGCAGCTG
TTGTTAAGGTGGTGGAAAGCCAGGCAGAACTTTATAGCTTAGAAAAGAATGAAGATGCTAGCCTAAGAAAGTTACAAGCA
GATGGACGCATCACGGAAGAACAGGCTAAAGCTTATAAAGAATACAATGATAAAAATGGAGGAGCAAATCGTAAAGTCAA
TGATTAA

Domains

Predicted by InterproScan.

• Prokaryotic N-terminal methylation motif (N_methyl) (11-34)

3D structure

• PDB: 5NCA

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comGC/cglC	Streptococcus pneumoniae TIGR4	100	100	1
comGC/cglC	Streptococcus pneumoniae Rx1	99.074	100	0.991
comGC/cglC	Streptococcus pneumoniae D39	99.074	100	0.991
comGC/cglC	Streptococcus pneumoniae R6	99.074	100	0.991
comGC/cglC	Streptococcus mitis SK321	94.444	100	0.944
comGC/cglC	Streptococcus mitis NCTC 12261	94.898	90.741	0.861
comYC	Streptococcus gordonii str. Challis substr. CH1	67.961	95.37	0.648
comYC	Streptococcus mutans UA140	62.745	94.444	0.593
comYC	Streptococcus mutans UA159	62.745	94.444	0.593
comYC	Streptococcus suis isolate S10	70.37	75	0.528
comGC	Lactococcus lactis subsp. cremoris KW2	53.922	94.444	0.509
comGC	Staphylococcus aureus MW2	50	79.63	0.398
comGC	Staphylococcus aureus N315	50	79.63	0.398
comGC	Latilactobacillus sakei subsp. sakei 23K	45.349	79.63	0.361