NTDB

Overview

Name	comGD/cglD	Type	Machinery gene
Locus tag	R4706_RS06335	Genome accession	NZ_CP137111
Coordinates	1263638..1264042 (+)	Length	134 a.a.
NCBI ID	WP_000588018.1	Uniprot ID	A0A0T7ZN89
Organism	Streptococcus pneumoniae strain 17023
Function	dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1258638..1269042

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4706_RS06310	-	1259762..1260820 (+)	1059	WP_044727686.1	zinc-dependent alcohol dehydrogenase family protein	-
R4706_RS06315	-	1260971..1261336 (+)	366	WP_000286415.1	DUF1033 family protein	-
R4706_RS06320	comGA/cglA/cilD	1261412..1262353 (+)	942	WP_317815369.1	competence type IV pilus ATPase ComGA	Machinery gene
R4706_RS06325	comGB/cglB	1262301..1263317 (+)	1017	WP_078102664.1	competence type IV pilus assembly protein ComGB	Machinery gene
R4706_RS06330	comGC/cglC	1263319..1263645 (+)	327	WP_000738627.1	comG operon protein ComGC	Machinery gene
R4706_RS06335	comGD/cglD	1263638..1264042 (+)	405	WP_000588018.1	competence type IV pilus minor pilin ComGD	Machinery gene
R4706_RS06340	comGE/cglE	1264005..1264307 (+)	303	WP_257890291.1	competence type IV pilus minor pilin ComGE	Machinery gene
R4706_RS06345	comGF/cglF	1264270..1264731 (+)	462	WP_044727689.1	competence type IV pilus minor pilin ComGF	Machinery gene
R4706_RS06350	comGG/cglG	1264709..1265122 (+)	414	WP_000265624.1	competence type IV pilus minor pilin ComGG	Machinery gene
R4706_RS06355	-	1265259..1265853 (+)	595	Protein_1240	class I SAM-dependent methyltransferase	-
R4706_RS06360	comYH	1265914..1266867 (+)	954	WP_044727690.1	class I SAM-dependent methyltransferase	Machinery gene
R4706_RS06365	-	1266918..1268108 (+)	1191	WP_000167765.1	acetate kinase	-
R4706_RS06370	-	1268109..1268240 (+)	132	WP_000768904.1	hypothetical protein	-
R4706_RS06375	rnpA	1268257..1268628 (+)	372	WP_000739246.1	ribonuclease P protein component	-

Sequence

Protein

Download Length: 134 a.a. Molecular weight: 14634.83 Da Isoelectric Point: 10.2164

                                >NTDB_id=895956 R4706_RS06335 WP_000588018.1 1263638..1264042(+) (comGD/cglD) [Streptococcus pneumoniae strain 17023]

MIKAFTMLESLLVLGLVSILALGLSGSVQSTFAAVEEQIFFMEFEELYRETQKRSVASQQKTSLNLDGQTISNGSQKLPV

PKGIQAPSGQSITFDRAGGNSSLAKVEFQTSKGAIRYQLYLGNGKIKRIKETKN

Nucleotide

Download Length: 405 bp

                                >NTDB_id=895956 R4706_RS06335 WP_000588018.1 1263638..1264042(+) (comGD/cglD) [Streptococcus pneumoniae strain 17023]

ATGATTAAGGCCTTTACCATGCTGGAAAGTCTCTTGGTTTTGGGTCTTGTGAGTATCCTTGCCTTGGGCTTGTCCGGATC

TGTTCAGTCCACTTTTGCGGCAGTAGAGGAACAGATTTTCTTTATGGAGTTTGAAGAACTCTATCGGGAAACCCAAAAAC

GCAGTGTAGCCAGTCAGCAAAAGACTAGTCTGAACTTAGATGGGCAGACGATTAGCAATGGCAGTCAAAAGTTGCCAGTC

CCTAAAGGAATTCAGGCCCCATCAGGCCAAAGTATTACATTTGACCGTGCTGGGGGCAATTCGTCCCTGGCTAAGGTTGA

ATTTCAGACCAGTAAAGGAGCGATTCGCTATCAATTATATCTAGGAAATGGAAAAATTAAACGCATTAAGGAAACAAAAA

ATTAG

Domains

No domain identified.

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A0T7ZN89

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comGD/cglD	Streptococcus pneumoniae TIGR4	98.507	100	0.985
comGD/cglD	Streptococcus pneumoniae Rx1	97.761	100	0.978
comGD/cglD	Streptococcus pneumoniae D39	97.761	100	0.978
comGD/cglD	Streptococcus pneumoniae R6	97.761	100	0.978
comGD/cglD	Streptococcus mitis SK321	97.015	100	0.97
comGD/cglD	Streptococcus mitis NCTC 12261	97.744	99.254	0.97
comYD	Streptococcus gordonii str. Challis substr. CH1	59.843	94.776	0.567
comYD	Streptococcus mutans UA140	50	95.522	0.478
comYD	Streptococcus mutans UA159	50	95.522	0.478

Detailed information NTG0895956