Detailed information    

insolico Bioinformatically predicted

Overview

Name   comYH   Type   Machinery gene
Locus tag   R4706_RS06360 Genome accession   NZ_CP137111
Coordinates   1265914..1266867 (+) Length   317 a.a.
NCBI ID   WP_044727690.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 17023     
Function   dsDNA binding to the cell surface; assembly of the pseudopilus (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1260914..1271867
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4706_RS06315 - 1260971..1261336 (+) 366 WP_000286415.1 DUF1033 family protein -
  R4706_RS06320 comGA/cglA/cilD 1261412..1262353 (+) 942 WP_317815369.1 competence type IV pilus ATPase ComGA Machinery gene
  R4706_RS06325 comGB/cglB 1262301..1263317 (+) 1017 WP_078102664.1 competence type IV pilus assembly protein ComGB Machinery gene
  R4706_RS06330 comGC/cglC 1263319..1263645 (+) 327 WP_000738627.1 comG operon protein ComGC Machinery gene
  R4706_RS06335 comGD/cglD 1263638..1264042 (+) 405 WP_000588018.1 competence type IV pilus minor pilin ComGD Machinery gene
  R4706_RS06340 comGE/cglE 1264005..1264307 (+) 303 WP_257890291.1 competence type IV pilus minor pilin ComGE Machinery gene
  R4706_RS06345 comGF/cglF 1264270..1264731 (+) 462 WP_044727689.1 competence type IV pilus minor pilin ComGF Machinery gene
  R4706_RS06350 comGG/cglG 1264709..1265122 (+) 414 WP_000265624.1 competence type IV pilus minor pilin ComGG Machinery gene
  R4706_RS06355 - 1265259..1265853 (+) 595 Protein_1240 class I SAM-dependent methyltransferase -
  R4706_RS06360 comYH 1265914..1266867 (+) 954 WP_044727690.1 class I SAM-dependent methyltransferase Machinery gene
  R4706_RS06365 - 1266918..1268108 (+) 1191 WP_000167765.1 acetate kinase -
  R4706_RS06370 - 1268109..1268240 (+) 132 WP_000768904.1 hypothetical protein -
  R4706_RS06375 rnpA 1268257..1268628 (+) 372 WP_000739246.1 ribonuclease P protein component -
  R4706_RS06380 - 1268603..1269427 (+) 825 WP_000727904.1 membrane protein insertase YidC -
  R4706_RS06385 jag 1269446..1270432 (+) 987 WP_044727692.1 RNA-binding cell elongation regulator Jag/EloR -
  R4706_RS06390 - 1270483..1271106 (+) 624 WP_000932654.1 hypothetical protein -

Sequence

Protein


Download         Length: 317 a.a.        Molecular weight: 35717.01 Da        Isoelectric Point: 4.3332

>NTDB_id=895960 R4706_RS06360 WP_044727690.1 1265914..1266867(+) (comYH) [Streptococcus pneumoniae strain 17023]
MDFEKIEQAYTYLLENVQVIQSDLATNFYDALVEQNSIYLDGETELNQVKDNNQALKRLALRKEEWLKTYQFLLMKAGQT
EPLQANHQFTPDAIALLLVFIVEELFKEEEITILEMGSGMGILGATFLTSLDKKVDYLGMEVDDLLIDLAASMADVIGLQ
AGFVQGDAVRPQMLKESDVVISDLPVGYYPDDAVALRHQVASSQEHTYAHHLLMEQGFKYLKSDGYAIFLAPSDLLTSPQ
SDLLKVWLKEEASLVAMISLPENLFANAKQSKTIFILQKKSEIAVEPFVYPLASLQDASVLMKFKKNFQKWTQGTEI

Nucleotide


Download         Length: 954 bp        

>NTDB_id=895960 R4706_RS06360 WP_044727690.1 1265914..1266867(+) (comYH) [Streptococcus pneumoniae strain 17023]
ATGGATTTTGAAAAAATTGAACAAGCTTATACCTATTTACTAGAGAATGTCCAAGTCATCCAAAGTGATTTGGCGACCAA
CTTTTATGACGCCTTGGTGGAGCAAAACAGCATCTATCTGGATGGTGAAACTGAGCTAAACCAGGTCAAAGACAACAATC
AGGCCCTTAAGCGTTTAGCACTACGCAAAGAAGAATGGCTCAAGACCTACCAGTTTCTCTTGATGAAGGCTGGGCAAACA
GAACCCTTGCAGGCCAATCACCAGTTTACACCGGATGCTATTGCTTTGCTTTTGGTGTTTATTGTGGAAGAGTTGTTTAA
AGAGGAGGAAATTACTATCCTCGAAATGGGTTCTGGGATGGGAATTCTAGGCGCTACTTTCTTGACCTCGCTTGATAAAA
AGGTGGATTACTTGGGAATGGAAGTGGATGATTTACTGATTGATCTGGCAGCTAGCATGGCAGATGTAATTGGTTTGCAG
GCTGGCTTTGTCCAAGGAGATGCCGTTCGTCCACAAATGCTCAAAGAAAGCGATGTGGTCATCAGTGACTTGCCTGTCGG
CTATTATCCTGATGATGCCGTTGCGTTGCGTCATCAAGTTGCTTCTAGCCAAGAACATACTTACGCCCATCACTTGCTCA
TGGAACAAGGGTTTAAGTACCTTAAGTCAGATGGATATGCTATTTTTCTAGCTCCGAGTGATTTGTTGACCAGTCCTCAA
AGTGATTTGTTGAAAGTCTGGTTGAAAGAGGAGGCAAGTCTGGTTGCTATGATTAGTCTGCCTGAAAATCTCTTTGCTAA
TGCTAAACAATCTAAGACTATTTTTATCCTACAGAAGAAAAGTGAAATAGCAGTGGAGCCTTTTGTTTATCCACTTGCTA
GCTTGCAAGATGCAAGTGTTTTAATGAAATTTAAAAAAAATTTTCAAAAATGGACTCAAGGTACTGAAATATAA

Domains

Predicted by InterproScan.

N-6 DNA Methylase (N6_Mtase)

(69-282)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comYH Streptococcus mutans UA140

54.952

98.738

0.543
  comYH Streptococcus mutans UA159

54.633

98.738

0.539