Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   R4706_RS02915 Genome accession   NZ_CP137111
Coordinates   587066..587653 (+) Length   195 a.a.
NCBI ID   WP_000205166.1    Uniprot ID   Q9ETN5
Organism   Streptococcus pneumoniae strain 17023     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 582066..592653
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4706_RS02880 - 582139..582522 (-) 384 WP_000877381.1 hypothetical protein -
  R4706_RS02885 - 583308..583427 (-) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  R4706_RS02890 cipB 583531..583680 (-) 150 WP_001808912.1 bacteriocin-like peptide BlpO Regulator
  R4706_RS02895 - 583924..584208 (-) 285 WP_050205793.1 Blp family class II bacteriocin -
  R4706_RS02905 - 586060..586263 (-) 204 WP_000411016.1 hypothetical protein -
  R4706_RS02910 - 586581..586784 (-) 204 WP_001093262.1 bacteriocin class II family protein -
  R4706_RS02915 comA/nlmT 587066..587653 (+) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  R4706_RS02920 blpA 587580..588848 (+) 1269 Protein_579 peptide cleavage/export ABC transporter BlpA -
  R4706_RS02925 comA/nlmT 589058..589222 (+) 165 WP_306420852.1 hypothetical protein Regulator
  R4706_RS02930 - 589233..590594 (+) 1362 WP_050233594.1 bacteriocin secretion accessory protein -
  R4706_RS02935 blpC 590651..590779 (+) 129 WP_000358815.1 quorum-sensing system pheromone BlpC -
  R4706_RS02940 - 590850..592190 (-) 1341 WP_001017646.1 sensor histidine kinase -

Sequence

Protein


Download         Length: 195 a.a.        Molecular weight: 22270.71 Da        Isoelectric Point: 9.6188

>NTDB_id=895926 R4706_RS02915 WP_000205166.1 587066..587653(+) (comA/nlmT) [Streptococcus pneumoniae strain 17023]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG

Nucleotide


Download         Length: 588 bp        

>NTDB_id=895926 R4706_RS02915 WP_000205166.1 587066..587653(+) (comA/nlmT) [Streptococcus pneumoniae strain 17023]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCGAGAGACTGTGGTGTCGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGGACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGACCTGTTCAAGCAGATAAAACGCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAACGCTTTTTCTATGAATGGACTGGAG
TAGCTATTTTTCTAGCTACCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCAAGCTTCCTTCC
TCTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTT
CTTATTATCTCCAAGGAATCTTGGATGA

Domains

Predicted by InterproScan.

Peptidase C39 family (Peptidase_C39)

(7-142)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB Q9ETN5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

59.89

93.333

0.559
  comA Streptococcus mitis NCTC 12261

54.891

94.359

0.518
  comA Streptococcus mitis SK321

54.348

94.359

0.513
  comA Streptococcus pneumoniae TIGR4

53.804

94.359

0.508
  comA Streptococcus pneumoniae Rx1

53.804

94.359

0.508
  comA Streptococcus pneumoniae D39

53.804

94.359

0.508
  comA Streptococcus pneumoniae R6

53.804

94.359

0.508
  comA Streptococcus gordonii str. Challis substr. CH1

52.717

94.359

0.497