Detailed information NTG0895918

Bioinformatically predicted

Overview

• Name: dprA/cilB/dalA
• Type: Machinery gene
• Locus tag: R4706_RS00845
• Genome accession: NZ_CP137111
• Coordinates: 175339..176187 (-)
• Length: 282 a.a.
• NCBI ID: WP_044727471.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain 17023
• Function: ssDNA binding; loading RecA onto ssDNA; competence shut-off (predicted from homology) DNA processing Competence regulation

Genomic Context

Location: 170339..181187

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4706_RS00830	-	170738..171097 (-)	360	WP_001237219.1	YbaN family protein	-
R4706_RS00835	topA	171203..173290 (-)	2088	WP_000179639.1	type I DNA topoisomerase	-
R4706_RS00840	-	173457..174500 (-)	1044	WP_025169634.1	TIGR00341 family protein	-
R4706_RS00845	dprA/cilB/dalA	175339..176187 (-)	849	WP_044727471.1	DNA-processing protein DprA	Machinery gene
R4706_RS00850	-	176283..176972 (-)	690	WP_044727470.1	CTP--phosphocholine cytidylyltransferase	-
R4706_RS00855	-	176984..177862 (-)	879	WP_000837609.1	DMT family transporter	-
R4706_RS00860	licA	177852..178721 (-)	870	WP_000411207.1	choline kinase LicA	-
R4706_RS00865	-	178738..179760 (-)	1023	WP_000609888.1	ribitol-5-phosphate dehydrogenase	-
R4706_RS00870	-	179765..180472 (-)	708	WP_000638482.1	2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase	-

Sequence

Protein

• Length: 282 a.a.
• Molecular weight: 31066.71 Da
• Isoelectric Point: 5.4047

>NTDB_id=895918 R4706_RS00845 WP_044727471.1 175339..176187(-) (dprA/cilB/dalA) [Streptococcus pneumoniae strain 17023]
MKITNYEIYKLKKSGLTNQQILKVLEYGENVDQELLLGDIADISGCRNPAVFMERYFQIDDAHLSKEFQKFPSFSILDDC
YPWDLSEIYDAPVLLFYKGNLDLLKFPKVAVVGSRACSKQGAKSVEKVIQGLENELVIVSGLAKGIDTAAHMAALQNGGK
TIAVIGTGLDVFYPKANKRLQDYIGNDHLLLSEYGSGEQPLKFHFPARNRIIAGLCRGVIVAEAKMRSGSLITCERAMEE
GRDVFAIPGSILDGLSDGCHHLIQEGAKLVTSGQDVLAEFEF

Nucleotide

• Length: 849 bp

>NTDB_id=895918 R4706_RS00845 WP_044727471.1 175339..176187(-) (dprA/cilB/dalA) [Streptococcus pneumoniae strain 17023]
ATGAAAATCACAAACTATGAAATCTATAAGTTAAAAAAATCAGGTTTGACCAATCAACAGATTTTGAAAGTGCTAGAATA
CGGTGAAAATGTTGATCAGGAGCTTTTGTTGGGTGATATTGCAGATATATCAGGTTGCCGTAATCCAGCCGTTTTTATGG
AACGTTATTTTCAGATAGACGATGCGCATTTGTCGAAAGAGTTTCAAAAATTTCCATCTTTTTCTATTTTAGATGACTGT
TATCCTTGGGATTTGAGTGAAATATATGATGCGCCTGTACTTTTATTTTACAAGGGAAATCTTGACCTCCTGAAATTCCC
GAAGGTAGCGGTCGTGGGCAGTCGTGCTTGTAGCAAACAGGGAGCTAAGTCAGTTGAAAAAGTCATTCAAGGCTTGGAAA
ATGAACTGGTTATTGTCAGTGGTCTGGCCAAGGGCATTGACACAGCAGCTCATATGGCAGCTCTTCAGAATGGCGGAAAA
ACCATTGCAGTGATTGGAACAGGACTGGATGTGTTTTATCCTAAAGCCAACAAACGCTTGCAAGACTACATCGGCAATGA
CCATCTGCTTCTCAGTGAATATGGATCTGGCGAACAACCTCTGAAATTTCATTTTCCTGCCCGTAATCGCATCATTGCTG
GACTTTGTCGTGGTGTGATTGTAGCAGAGGCTAAGATGCGTTCAGGTAGTCTCATTACCTGTGAGCGAGCAATGGAAGAA
GGACGCGATGTCTTTGCTATTCCTGGTAGCATTTTAGATGGACTATCAGACGGTTGCCATCATTTGATTCAAGAAGGAGC
AAAATTGGTCACCAGTGGGCAAGATGTTCTTGCGGAATTTGAATTTTAA

Domains

Predicted by InterproScan.

• DNA recombination-mediator protein A (DNA_processg_A) (75-271)

• DNA processing protein A sterile alpha motif domain (SAM_DprA) (3-64)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
dprA/cilB/dalA	Streptococcus pneumoniae Rx1	99.291	100	0.993
dprA/cilB/dalA	Streptococcus pneumoniae D39	99.291	100	0.993
dprA/cilB/dalA	Streptococcus pneumoniae R6	99.291	100	0.993
dprA/cilB/dalA	Streptococcus pneumoniae TIGR4	99.291	100	0.993
dprA/cilB/dalA	Streptococcus mitis NCTC 12261	97.872	100	0.979
dprA/cilB/dalA	Streptococcus mitis SK321	97.163	100	0.972
dprA	Streptococcus mutans UA159	63.571	99.291	0.631
dprA	Lactococcus lactis subsp. cremoris KW2	55.357	99.291	0.55
dprA	Staphylococcus aureus N315	37.102	100	0.372
dprA	Haemophilus influenzae Rd KW20	38.202	94.681	0.362