Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   R4712_RS02855 Genome accession   NZ_CP137110
Coordinates   572051..573616 (+) Length   521 a.a.
NCBI ID   WP_308410653.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 16H2041     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 567051..578616
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4712_RS02815 - 567525..567908 (-) 384 WP_016398494.1 hypothetical protein -
  R4712_RS02820 - 568537..568869 (-) 333 WP_224757293.1 immunity protein -
  R4712_RS02825 - 569389..569508 (-) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  R4712_RS10850 - 569511..569576 (-) 66 Protein_564 ComC/BlpC family peptide pheromone/bacteriocin -
  R4712_RS02830 cipB 569612..569761 (-) 150 WP_001809846.1 bacteriocin-like peptide BlpO Regulator
  R4712_RS02835 blpK 570005..570253 (-) 249 WP_000379965.1 bacteriocin-like peptide BlpK -
  R4712_RS02840 blpJ 570322..570591 (-) 270 WP_001093248.1 bacteriocin-like peptide BlpJ -
  R4712_RS02845 blpI 571058..571255 (-) 198 WP_001093259.1 bacteriocin-like peptide BlpI -
  R4712_RS02850 comA/nlmT 571537..572124 (+) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  R4712_RS02855 comA/nlmT 572051..573616 (+) 1566 WP_308410653.1 peptide cleavage/export ABC transporter Regulator
  R4712_RS02860 - 573705..575066 (+) 1362 WP_001069060.1 bacteriocin secretion accessory protein -
  R4712_RS02865 blpC 575123..575251 (+) 129 WP_000358815.1 quorum-sensing system pheromone BlpC -
  R4712_RS02870 - 575322..576662 (-) 1341 WP_001017642.1 sensor histidine kinase -
  R4712_RS02875 comE/blpR 576676..577413 (-) 738 WP_001219120.1 LytTR family DNA-binding domain-containing protein Regulator
  R4712_RS02880 - 577418..577756 (-) 339 WP_000876675.1 LytTR family DNA-binding domain-containing protein -
  R4712_RS02885 - 578032..578361 (+) 330 WP_000132572.1 hypothetical protein -

Sequence

Protein


Download         Length: 521 a.a.        Molecular weight: 58621.18 Da        Isoelectric Point: 6.2485

>NTDB_id=895847 R4712_RS02855 WP_308410653.1 572051..573616(+) (comA/nlmT) [Streptococcus pneumoniae strain 16H2041]
MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIF
ELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMFIIFSFMKPFE
KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTKLVLNILILWFG
AQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLS
YKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINYLPQQAYIF
NGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKAPVLILDEATSG
LDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLD

Nucleotide


Download         Length: 1566 bp        

>NTDB_id=895847 R4712_RS02855 WP_308410653.1 572051..573616(+) (comA/nlmT) [Streptococcus pneumoniae strain 16H2041]
ATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTCTTACTATCTCCAAGGAATCTTGGATGAATACAT
TCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGGTTATCACCTATATCCTCCAACAAGTCATGAGCT
TCTCCAGAGATTATCTCCTAACCGTTCTGAGTCAGAGATTAAGTATTGATGTGATTTTATCCTATATTCGCCATATTTTT
GAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCATTTCACGATTCACAGATGCTAACTCTATTATAGA
TGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTCTGATTCTTGTAGGAGGCGTCTTACTGGCACAAA
ACCCTAATCTCTTCCTTCTTTCTCTTATTTCCATTCCTATATACATGTTCATCATCTTTTCTTTTATGAAACCTTTCGAA
AAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGCCATTATCGAAGATATCAACGGGATTGAAACTAT
AAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCGAATTTGTAGATTATTTGGAAAAATCCTTTAAGC
TCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAATTAGTTCTGAATATCCTTATCCTATGGTTTGGC
GCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTACCTTTAACACACTTTTTTCTTACTTTACAACTCC
TATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGGTCGCTAATAACCGTTTGAACGAAGTCTATCTAG
TCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTCCATTCACATTTTTTGATGGGCGATATTGAATTTGATGACCTTTCT
TATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCACGATTAAACAAGGAGATAAGGTTAGCCTAGTTGG
AGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCTTTGAACCCTACAAAGGACATATTTCTATCA
ATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATTAATTACCTACCACAACAAGCCTATATCTTT
AATGGCTCTATCTTGGAAAACTTAACTTTGGGCGGTAATCATATGATTAGCCAAGAAGATATTCTAAGAGCTTGTGAATT
AGCTGAAATTCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAACTCAGCTCTCTGATGGAGCTGGTCTATCAGGAG
GACAAAAGCAACGAATAGCCCTCGCTCGTGCTCTTTTAACTAAAGCTCCTGTTTTAATACTAGACGAAGCTACTAGCGGT
CTTGATGTCTTGACTGAGAAAAAGGTTATAGATAATCTTATGTCTCTAACTGATAAAACCATTCTCTTTGTAGCCCATCG
TCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACTAG

Domains

Predicted by InterproScan.

ABC transporter transmembrane region (ABC_membrane)

(2-268)

ABC transporter (ABC_tran)

(330-479)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

73.512

100

0.735
  comA Streptococcus mitis NCTC 12261

68.391

100

0.685
  comA Streptococcus pneumoniae Rx1

68.008

100

0.681
  comA Streptococcus pneumoniae D39

68.008

100

0.681
  comA Streptococcus pneumoniae R6

68.008

100

0.681
  comA Streptococcus mitis SK321

67.816

100

0.679
  comA Streptococcus pneumoniae TIGR4

67.625

100

0.678
  comA Streptococcus gordonii str. Challis substr. CH1

67.304

100

0.676