Detailed information    

insolico Bioinformatically predicted

Overview

Name   comA/nlmT   Type   Regulator
Locus tag   R4711_RS02950 Genome accession   NZ_CP137107
Coordinates   584278..585921 (+) Length   547 a.a.
NCBI ID   WP_075270826.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 15H4024     
Function   transport of ComC (predicted from homology)   
Competence regulation

Genomic Context

Location: 579278..590921
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4711_RS02900 - 579975..580094 (-) 120 WP_000346296.1 PncF family bacteriocin immunity protein -
  R4711_RS02905 cipB 580198..580347 (-) 150 WP_001813641.1 bacteriocin-like peptide BlpO Regulator
  R4711_RS02910 blpN 580591..580794 (-) 204 WP_001099492.1 two-peptide bacteriocin subunit BlpN -
  R4711_RS02915 blpM 580810..581064 (-) 255 WP_000379879.1 two-peptide bacteriocin subunit BlpM -
  R4711_RS02920 - 581266..582071 (-) 806 Protein_581 IS5 family transposase -
  R4711_RS02925 - 582269..582673 (-) 405 WP_000846944.1 hypothetical protein -
  R4711_RS02930 - 582670..582834 (-) 165 WP_000727118.1 hypothetical protein -
  R4711_RS02935 - 583131..583250 (-) 120 WP_000346298.1 PncF family bacteriocin immunity protein -
  R4711_RS02940 blpU 583253..583483 (-) 231 WP_001093268.1 bacteriocin-like peptide BlpU -
  R4711_RS02945 comA/nlmT 583764..584351 (+) 588 WP_000205166.1 cysteine peptidase family C39 domain-containing protein Regulator
  R4711_RS02950 comA/nlmT 584278..585921 (+) 1644 WP_075270826.1 peptide cleavage/export ABC transporter Regulator
  R4711_RS02955 - 585932..587293 (+) 1362 WP_001069060.1 bacteriocin secretion accessory protein -
  R4711_RS02960 blpC 587350..587505 (+) 156 WP_000358814.1 quorum-sensing system pheromone BlpC -
  R4711_RS02965 - 587550..588890 (-) 1341 WP_001099895.1 sensor histidine kinase -
  R4711_RS02970 comE/blpR 588904..589641 (-) 738 WP_001219146.1 response regulator transcription factor Regulator
  R4711_RS02975 - 589646..589984 (-) 339 WP_000682132.1 LytTR family DNA-binding domain-containing protein -
  R4711_RS02980 - 590261..590590 (+) 330 WP_000132572.1 hypothetical protein -

Sequence

Protein


Download         Length: 547 a.a.        Molecular weight: 61643.61 Da        Isoelectric Point: 6.5088

>NTDB_id=895615 R4711_RS02950 WP_075270826.1 584278..585921(+) (comA/nlmT) [Streptococcus pneumoniae strain 15H4024]
MVLSSLLVTIINIGGSYYLQGILDEYIPNQMKSTLGIISVGLVITYILQQVMSFSRDYLLTVLSQRLSIDVILSYIRHIF
ELPMSFFATRRTGEIISRFTDANSIIDALASTILSLFLDVSILILVGGVLLAQNPNLFLLSLISIPIYMFIIFSFMKPFE
KMNHDVMQSNSMVSSAIIEDINGIETIKSLTSEENRYQNIDSEFVDYLEKSFKLSKYSILQTSLKQGTKLVLNILILWFG
AQLVMSSKISIGQLITFNTLFSYFTTPMENIINLQTKLQSAKVANNRLNEVYLVESEFQVQENPVHSHFLMGDIEFDDLS
YKYGFGRDTLTDINLTIKQGDKVSLVGVSGSGKTTLAKMIVNFFEPYKGHISINHQDIKNIDKKVLRRHINYLPQQAYIF
NGSILENLTLGGNHMISQEDILRACELAEIRQDIERMPMGYQTQLSDGAGLSGGQKQRIALARALLTKAPVLILDEATSG
LDVLTEKKVIDNLMSLTDKTILFVAHRLSIAERTNRVIVLDQGKIIEVGSHQELMQAQGFYHHLFNK

Nucleotide


Download         Length: 1644 bp        

>NTDB_id=895615 R4711_RS02950 WP_075270826.1 584278..585921(+) (comA/nlmT) [Streptococcus pneumoniae strain 15H4024]
ATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTTCTTACTATCTCCAAGGAATCTTGGATGAATACAT
TCCAAATCAGATGAAATCAACTTTAGGAATCATCTCAGTTGGTCTGGTTATCACCTATATCCTCCAACAAGTCATGAGCT
TCTCCAGAGATTATCTCCTAACCGTTCTGAGTCAGAGATTAAGTATTGATGTGATTTTATCCTATATTCGCCATATTTTT
GAACTTCCCATGTCTTTCTTTGCGACACGTCGTACAGGAGAAATCATTTCACGGTTCACAGATGCTAACTCTATTATAGA
TGCCTTGGCTTCTACCATTCTTTCTCTTTTTCTGGATGTTTCTATTCTGATTCTTGTAGGAGGCGTCTTACTGGCACAAA
ACCCTAATCTCTTCCTTCTTTCTCTTATTTCCATTCCTATATACATGTTCATCATCTTTTCTTTTATGAAACCTTTCGAA
AAAATGAACCATGATGTCATGCAAAGTAATTCTATGGTTAGCTCTGCCATTATCGAAGATATCAACGGGATTGAAACTAT
AAAGTCGCTCACGAGTGAAGAAAATCGCTATCAAAATATAGACAGCGAATTTGTAGATTATTTGGAAAAATCCTTTAAGC
TCAGTAAATATTCTATTTTACAAACGAGTTTAAAGCAGGGAACAAAATTAGTTCTGAATATCCTTATCCTATGGTTTGGC
GCTCAATTAGTCATGTCGAGTAAAATTTCTATCGGTCAGCTGATTACCTTTAACACACTTTTTTCTTACTTTACAACTCC
TATGGAAAATATTATCAACCTCCAAACCAAACTCCAATCTGCGAAGGTCGCTAATAACCGTTTGAACGAAGTCTATCTAG
TCGAATCTGAATTTCAAGTTCAAGAAAACCCTGTCCATTCACATTTTTTGATGGGCGATATTGAATTTGATGACCTTTCT
TATAAGTATGGTTTTGGACGAGATACCTTAACAGATATTAATCTCACGATTAAACAAGGAGATAAGGTTAGCCTAGTTGG
AGTTAGTGGTTCTGGTAAAACAACTTTAGCCAAAATGATTGTCAATTTCTTTGAACCCTACAAAGGACATATTTCTATCA
ATCATCAGGATATTAAAAACATTGATAAAAAAGTCTTGCGCCGTCATATTAATTACCTACCACAACAAGCCTATATCTTT
AATGGCTCTATCTTGGAAAACTTAACTTTGGGCGGTAATCATATGATTAGCCAAGAAGATATTCTAAGAGCTTGTGAATT
AGCTGAAATTCGTCAAGACATTGAAAGAATGCCTATGGGCTATCAAACTCAGCTCTCTGATGGAGCTGGTCTATCAGGAG
GACAAAAGCAACGAATAGCCCTCGCTCGTGCTCTTTTAACTAAAGCTCCTGTTTTAATACTAGACGAAGCTACTAGCGGT
CTTGATGTCTTGACTGAGAAAAAGGTTATAGATAATCTTATGTCTCTAACTGATAAAACCATTCTCTTTGTAGCCCATCG
TCTCAGTATAGCCGAACGAACCAACCGTGTCATTGTTCTTGACCAGGGGAAAATCATTGAAGTTGGTAGTCACCAAGAGT
TAATGCAGGCGCAAGGTTTCTACCATCATCTATTCAATAAATAA

Domains

Predicted by InterproScan.

ABC transporter (ABC_tran)

(330-479)

ABC transporter transmembrane region (ABC_membrane)

(2-268)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comA/nlmT Streptococcus mutans UA159

73.077

99.817

0.729
  comA Streptococcus mitis NCTC 12261

67.824

100

0.678
  comA Streptococcus pneumoniae D39

67.459

100

0.675
  comA Streptococcus pneumoniae R6

67.459

100

0.675
  comA Streptococcus pneumoniae Rx1

67.459

100

0.675
  comA Streptococcus mitis SK321

67.276

100

0.673
  comA Streptococcus gordonii str. Challis substr. CH1

67.153

100

0.673
  comA Streptococcus pneumoniae TIGR4

67.093

100

0.671