Detailed information NTG0895614

Bioinformatically predicted

Overview

• Name: comA/nlmT
• Type: Regulator
• Locus tag: R4711_RS02945
• Genome accession: NZ_CP137107
• Coordinates: 583764..584351 (+)
• Length: 195 a.a.
• NCBI ID: WP_000205166.1
• Uniprot ID: Q9ETN5
• Organism: Streptococcus pneumoniae strain 15H4024
• Function: transport of ComC (predicted from homology) Competence regulation

Genomic Context

Location: 578764..589351

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
R4711_RS02895	-	578806..579189 (-)	384	WP_000877378.1	hypothetical protein	-
R4711_RS02900	-	579975..580094 (-)	120	WP_000346296.1	PncF family bacteriocin immunity protein	-
R4711_RS02905	cipB	580198..580347 (-)	150	WP_001813641.1	bacteriocin-like peptide BlpO	Regulator
R4711_RS02910	blpN	580591..580794 (-)	204	WP_001099492.1	two-peptide bacteriocin subunit BlpN	-
R4711_RS02915	blpM	580810..581064 (-)	255	WP_000379879.1	two-peptide bacteriocin subunit BlpM	-
R4711_RS02920	-	581266..582071 (-)	806	Protein_581	IS5 family transposase	-
R4711_RS02925	-	582269..582673 (-)	405	WP_000846944.1	hypothetical protein	-
R4711_RS02930	-	582670..582834 (-)	165	WP_000727118.1	hypothetical protein	-
R4711_RS02935	-	583131..583250 (-)	120	WP_000346298.1	PncF family bacteriocin immunity protein	-
R4711_RS02940	blpU	583253..583483 (-)	231	WP_001093268.1	bacteriocin-like peptide BlpU	-
R4711_RS02945	comA/nlmT	583764..584351 (+)	588	WP_000205166.1	cysteine peptidase family C39 domain-containing protein	Regulator
R4711_RS02950	comA/nlmT	584278..585921 (+)	1644	WP_075270826.1	peptide cleavage/export ABC transporter	Regulator
R4711_RS02955	-	585932..587293 (+)	1362	WP_001069060.1	bacteriocin secretion accessory protein	-
R4711_RS02960	blpC	587350..587505 (+)	156	WP_000358814.1	quorum-sensing system pheromone BlpC	-
R4711_RS02965	-	587550..588890 (-)	1341	WP_001099895.1	sensor histidine kinase	-

Sequence

Protein

• Length: 195 a.a.
• Molecular weight: 22270.71 Da
• Isoelectric Point: 9.6188

>NTDB_id=895614 R4711_RS02945 WP_000205166.1 583764..584351(+) (comA/nlmT) [Streptococcus pneumoniae strain 15H4024]
MTSYKRTFVPQIDARDCGVAALASIAKFYGSDFSLAHLRELAKTNKEGTTALGIVKAADEMGFETRPVQADKTLFDMSDV
PYPFIVHVNKEGKLQHYYVVYQTKKDYLIIGDPDPSVKITKMSKERFFYEWTGVAIFLATKPSYQPHKDKKNGLLSKLPS
SDFQTKISHCLHCSLKLIGHYYQYRWFLLSPRNLG

Nucleotide

• Length: 588 bp

>NTDB_id=895614 R4711_RS02945 WP_000205166.1 583764..584351(+) (comA/nlmT) [Streptococcus pneumoniae strain 15H4024]
ATGACTTCTTATAAACGTACATTTGTTCCTCAAATAGATGCGAGAGACTGTGGTGTCGCTGCCTTAGCCTCGATTGCTAA
ATTCTATGGTTCAGATTTTTCTCTAGCTCACTTGAGAGAACTTGCAAAGACCAATAAAGAAGGGACGACTGCTCTTGGCA
TTGTAAAAGCCGCTGATGAAATGGGCTTTGAAACAAGACCTGTTCAAGCAGATAAAACGCTCTTTGACATGAGTGATGTC
CCCTATCCATTTATCGTTCACGTTAACAAAGAAGGAAAACTCCAACATTACTATGTTGTCTATCAAACAAAGAAAGACTA
TCTGATTATTGGTGATCCTGACCCTTCTGTAAAAATCACTAAAATGTCAAAAGAACGCTTTTTCTATGAATGGACTGGAG
TAGCTATTTTTCTAGCTACCAAACCCAGCTATCAACCCCATAAAGATAAAAAGAATGGTCTACTAAGCAAGCTTCCTTCC
TCTGATTTTCAAACAAAAATCTCTCATTGCTTACATTGTTCTCTCAAGCTTATTGGTCACTATTATCAATATAGGTGGTT
CTTACTATCTCCAAGGAATCTTGGATGA

Domains

Predicted by InterproScan.

• Peptidase C39 family (Peptidase_C39) (7-142)

3D structure

• AlphaFold DB: Q9ETN5

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comA/nlmT	Streptococcus mutans UA159	59.89	93.333	0.559
comA	Streptococcus mitis NCTC 12261	54.891	94.359	0.518
comA	Streptococcus mitis SK321	54.348	94.359	0.513
comA	Streptococcus pneumoniae TIGR4	53.804	94.359	0.508
comA	Streptococcus pneumoniae Rx1	53.804	94.359	0.508
comA	Streptococcus pneumoniae D39	53.804	94.359	0.508
comA	Streptococcus pneumoniae R6	53.804	94.359	0.508
comA	Streptococcus gordonii str. Challis substr. CH1	52.717	94.359	0.497