Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   R4710_RS10325 Genome accession   NZ_CP137101
Coordinates   1968660..1969310 (+) Length   216 a.a.
NCBI ID   WP_317804695.1    Uniprot ID   -
Organism   Streptococcus pneumoniae strain 16P2012-2     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1963660..1974310
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  R4710_RS10295 - 1964144..1964359 (+) 216 WP_001232082.1 YozE family protein -
  R4710_RS10300 - 1964445..1965413 (+) 969 WP_000658183.1 PhoH family protein -
  R4710_RS10305 - 1965606..1966106 (+) 501 WP_000566988.1 GNAT family N-acetyltransferase -
  R4710_RS10310 - 1966109..1966435 (+) 327 Protein_1997 TfoX/Sxy family protein -
  R4710_RS10315 ald 1966736..1967847 (-) 1112 Protein_1998 alanine dehydrogenase -
  R4710_RS10320 - 1968024..1968593 (+) 570 WP_000443743.1 GNAT family N-acetyltransferase -
  R4710_RS10325 comEA/celA/cilE 1968660..1969310 (+) 651 WP_317804695.1 helix-hairpin-helix domain-containing protein Machinery gene
  R4710_RS10330 comEC/celB 1969294..1971534 (+) 2241 WP_317804697.1 DNA internalization-related competence protein ComEC/Rec2 Machinery gene
  R4710_RS10335 - 1971713..1971901 (+) 189 WP_001809102.1 hypothetical protein -
  R4710_RS10340 - 1971933..1972520 (+) 588 WP_000933542.1 ATP-binding cassette domain-containing protein -
  R4710_RS10345 - 1972524..1973705 (+) 1182 WP_050245203.1 ABC transporter permease -

Sequence

Protein


Download         Length: 216 a.a.        Molecular weight: 23271.69 Da        Isoelectric Point: 5.5171

>NTDB_id=895217 R4710_RS10325 WP_317804695.1 1968660..1969310(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain 16P2012-2]
MEAIIEKIREYKIIVICTGLGLIVGGFFLLKPAPQTPVKETNLQAEVAAVSKDLVSEKEVNKEEKEEPLEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAVSQQTGLGTASSISKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD

Nucleotide


Download         Length: 651 bp        

>NTDB_id=895217 R4710_RS10325 WP_317804695.1 1968660..1969310(+) (comEA/celA/cilE) [Streptococcus pneumoniae strain 16P2012-2]
ATGGAAGCAATTATCGAGAAAATCAGAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGATTGTAGGAGGATT
TTTCCTGCTAAAACCAGCTCCACAAACACCTGTCAAAGAGACGAATTTGCAGGCTGAAGTCGCAGCTGTTTCCAAGGATT
TGGTATCCGAAAAGGAAGTGAACAAGGAAGAAAAGGAAGAACCCCTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAAGCAGTTAGCCAACAGACTGGTTTGGGGACAGCTTCTTCAATAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCT
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATCGACCATCGTGAGGCAAATGG
CAAGTTCAAATCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGCCAAGACTATAGAAAAGTTAAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterproScan.

Helix-hairpin-helix motif (HHH_3)

(151-214)

SLBB domain (SLBB)

(76-126)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus pneumoniae D39

98.611

100

0.986
  comEA/celA/cilE Streptococcus pneumoniae Rx1

98.611

100

0.986
  comEA/celA/cilE Streptococcus pneumoniae R6

98.611

100

0.986
  comEA/celA/cilE Streptococcus mitis NCTC 12261

95.833

100

0.958
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

95.833

100

0.958
  comEA/celA/cilE Streptococcus mitis SK321

89.815

100

0.898
  comEA Lactococcus lactis subsp. cremoris KW2

43.172

100

0.454
  comEA Latilactobacillus sakei subsp. sakei 23K

33.613

100

0.37
  comEA Bacillus subtilis subsp. subtilis str. 168

41.579

87.963

0.366