Detailed information    

insolico Bioinformatically predicted

Overview


Name   dprA   Type   Machinery gene
Locus tag   RJD36_RS06275 Genome accession   NZ_CP136943
Coordinates   1212539..1213381 (+) Length   280 a.a.
NCBI ID   WP_003064756.1    Uniprot ID   E0PDM2
Organism   Streptococcus pasteurianus strain WUSP082     
Function   ssDNA binding; loading RecA onto ssDNA (predicted from homology)   
DNA processing

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 1183072..1233557 1212539..1213381 within 0


Gene organization within MGE regions


Location: 1183072..1233557
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RJD36_RS06135 (RJD36_06135) - 1183072..1183263 (+) 192 WP_043028879.1 calcium-binding protein -
  RJD36_RS06140 (RJD36_06140) - 1183247..1183798 (+) 552 WP_317751459.1 hypothetical protein -
  RJD36_RS06145 (RJD36_06145) - 1183849..1189323 (+) 5475 WP_398578251.1 DEAD/DEAH box helicase family protein -
  RJD36_RS06150 (RJD36_06150) - 1189821..1191338 (+) 1518 Protein_1149 reverse transcriptase domain-containing protein -
  RJD36_RS06160 (RJD36_06160) - 1192717..1193814 (+) 1098 WP_398578252.1 hypothetical protein -
  RJD36_RS06165 (RJD36_06165) - 1194145..1194504 (+) 360 WP_117508721.1 SAG1252 family conjugative relaxosome accessory protein -
  RJD36_RS06170 (RJD36_06170) - 1194514..1194879 (+) 366 WP_117508722.1 MobC family plasmid mobilization relaxosome protein -
  RJD36_RS06175 (RJD36_06175) - 1194866..1195888 (+) 1023 Protein_1154 SAG1250 family conjugative relaxase -
  RJD36_RS06180 (RJD36_06180) - 1195964..1197069 (+) 1106 WP_249551291.1 IS3 family transposase -
  RJD36_RS06185 (RJD36_06185) tnpB 1197193..1197420 (+) 228 WP_230254186.1 IS66 family insertion sequence element accessory protein TnpB -
  RJD36_RS06190 (RJD36_06190) - 1197417..1197559 (+) 143 Protein_1157 transposase -
  RJD36_RS06195 (RJD36_06195) - 1197640..1198529 (-) 890 Protein_1158 IS3 family transposase -
  RJD36_RS06200 (RJD36_06200) - 1198620..1199336 (-) 717 WP_117508894.1 CPBP family intramembrane glutamic endopeptidase -
  RJD36_RS06205 (RJD36_06205) - 1200086..1200259 (-) 174 WP_153308183.1 hypothetical protein -
  RJD36_RS06210 (RJD36_06210) - 1200253..1200417 (+) 165 WP_153308184.1 hypothetical protein -
  RJD36_RS06215 (RJD36_06215) - 1201931..1203036 (+) 1106 WP_249551291.1 IS3 family transposase -
  RJD36_RS06220 (RJD36_06220) - 1203081..1204562 (-) 1482 Protein_1163 Nramp family divalent metal transporter -
  RJD36_RS06225 (RJD36_06225) - 1204867..1205255 (+) 389 Protein_1164 transposase -
  RJD36_RS06235 (RJD36_06235) - 1206754..1206882 (+) 129 Protein_1166 peptidase -
  RJD36_RS06240 (RJD36_06240) - 1206910..1207272 (+) 363 WP_142917765.1 LPXTG cell wall anchor domain-containing protein -
  RJD36_RS06245 (RJD36_06245) - 1207763..1207978 (+) 216 WP_000498035.1 helix-turn-helix domain-containing protein -
  RJD36_RS06250 (RJD36_06250) - 1208367..1208600 (+) 234 WP_047210205.1 hypothetical protein -
  RJD36_RS06255 (RJD36_06255) - 1208688..1210196 (+) 1509 WP_106474485.1 tyrosine-type recombinase/integrase -
  RJD36_RS06260 (RJD36_06260) ylqF 1210291..1211145 (+) 855 WP_003064765.1 ribosome biogenesis GTPase YlqF -
  RJD36_RS06265 (RJD36_06265) - 1211132..1211911 (+) 780 WP_117508882.1 ribonuclease HII -
  RJD36_RS06270 (RJD36_06270) - 1211913..1212464 (+) 552 WP_003064760.1 sugar O-acetyltransferase -
  RJD36_RS06275 (RJD36_06275) dprA 1212539..1213381 (+) 843 WP_003064756.1 DNA-processing protein DprA Machinery gene
  RJD36_RS06280 (RJD36_06280) topA 1213758..1215899 (+) 2142 WP_048791149.1 type I DNA topoisomerase -
  RJD36_RS06285 (RJD36_06285) - 1216047..1216712 (+) 666 WP_048791148.1 SatD family protein -
  RJD36_RS06290 (RJD36_06290) - 1216712..1217431 (+) 720 WP_082144658.1 DUF3307 domain-containing protein -
  RJD36_RS06295 (RJD36_06295) - 1217448..1217930 (+) 483 WP_003064748.1 hypothetical protein -
  RJD36_RS06300 (RJD36_06300) trmFO 1218107..1219444 (+) 1338 WP_058692307.1 methylenetetrahydrofolate--tRNA-(uracil(54)- C(5))-methyltransferase (FADH(2)-oxidizing) TrmFO -
  RJD36_RS06305 (RJD36_06305) - 1219553..1219762 (+) 210 WP_240208141.1 hypothetical protein -
  RJD36_RS06310 (RJD36_06310) - 1220444..1221196 (+) 753 WP_003064738.1 ABC transporter ATP-binding protein -
  RJD36_RS06315 (RJD36_06315) - 1221198..1223177 (+) 1980 WP_013851819.1 FtsX-like permease family protein -
  RJD36_RS06320 (RJD36_06320) - 1223265..1223927 (+) 663 WP_172456417.1 response regulator transcription factor -
  RJD36_RS06325 (RJD36_06325) - 1223924..1224871 (+) 948 WP_048791145.1 HAMP domain-containing sensor histidine kinase -
  RJD36_RS06330 (RJD36_06330) - 1224955..1225635 (+) 681 WP_003064733.1 XRE family transcriptional regulator -
  RJD36_RS06335 (RJD36_06335) xerS 1225742..1226812 (-) 1071 WP_003064732.1 tyrosine recombinase XerS -
  RJD36_RS06340 (RJD36_06340) - 1227078..1227539 (-) 462 WP_240208139.1 RNase H family protein -
  RJD36_RS06345 (RJD36_06345) - 1228062..1229167 (+) 1106 WP_249551291.1 IS3 family transposase -
  RJD36_RS06350 (RJD36_06350) - 1229409..1230314 (-) 906 WP_317749865.1 hypothetical protein -
  RJD36_RS06355 (RJD36_06355) - 1230441..1230719 (-) 279 WP_317581319.1 hypothetical protein -
  RJD36_RS06360 (RJD36_06360) - 1230695..1232731 (-) 2037 WP_287935667.1 N-6 DNA methylase -
  RJD36_RS06365 (RJD36_06365) - 1233012..1233557 (-) 546 WP_003064722.1 hypothetical protein -

Sequence


Protein


Download         Length: 280 a.a.        Molecular weight: 31027.10 Da        Isoelectric Point: 8.3615

>NTDB_id=893551 RJD36_RS06275 WP_003064756.1 1212539..1213381(+) (dprA) [Streptococcus pasteurianus strain WUSP082]
MNNFELFKLKKAGLTNLNILAILDYQEKQEKSLSLRNMAVVSKCKNPILFMEKYKALDIKELRKEFNCFPSVSILDDEYP
LELKHCYNPPVLLFYQGNLELLNRPKMAVVGARTASATGTKSVQKIVKELGNHFVIVSGLARGIDTSAHLSSLKNGGASI
AVIGCGLDVYYPKENKQLQEYMVKNHLVLSEYVAGEAPLKFHFPERNRIIAGLSQGVIVVEAKLRSGSLITCERALEEGR
DVFAIPGNILDGKSDGCHHLIKEGAKCVTSGLDILSEYQI

Nucleotide


Download         Length: 843 bp        

>NTDB_id=893551 RJD36_RS06275 WP_003064756.1 1212539..1213381(+) (dprA) [Streptococcus pasteurianus strain WUSP082]
ATGAATAATTTTGAATTGTTTAAATTAAAAAAAGCAGGATTAACAAATCTTAATATTTTAGCTATTTTGGATTATCAAGA
AAAGCAAGAGAAATCACTATCTTTGCGTAATATGGCAGTCGTCTCAAAATGTAAAAATCCTATCCTTTTTATGGAAAAAT
ACAAAGCACTGGACATCAAAGAATTGCGCAAAGAATTTAATTGTTTTCCTAGTGTTTCCATACTAGATGACGAATACCCA
TTAGAACTCAAACATTGTTATAATCCACCTGTTTTGCTGTTTTATCAAGGAAATTTAGAATTACTCAATCGCCCAAAAAT
GGCAGTAGTAGGAGCAAGAACAGCATCAGCAACAGGGACAAAATCCGTACAGAAAATTGTCAAAGAACTCGGGAATCATT
TTGTTATCGTTAGTGGGTTGGCGCGTGGCATTGATACCAGTGCGCATTTATCATCTCTAAAAAACGGTGGTGCATCGATT
GCCGTTATCGGTTGTGGACTGGACGTTTATTATCCCAAAGAAAATAAGCAGTTGCAGGAGTACATGGTTAAAAATCACCT
CGTATTAAGTGAGTACGTAGCAGGAGAAGCACCGCTGAAATTCCATTTTCCAGAGCGAAATCGTATTATTGCAGGTTTAT
CACAAGGCGTTATCGTAGTAGAAGCTAAGCTGCGCTCAGGCAGTTTGATTACGTGCGAAAGAGCATTGGAAGAAGGACGA
GACGTTTTTGCCATTCCAGGAAATATTTTAGATGGGAAATCTGATGGCTGTCATCATTTGATAAAAGAGGGCGCAAAATG
CGTCACATCAGGCTTAGATATCCTTTCGGAATATCAAATATAA


Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure
  AlphaFold DB E0PDM2

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  dprA Streptococcus mutans UA159

74.46

99.286

0.739

  dprA/cilB/dalA Streptococcus mitis NCTC 12261

63.929

100

0.639

  dprA/cilB/dalA Streptococcus pneumoniae Rx1

63.929

100

0.639

  dprA/cilB/dalA Streptococcus pneumoniae D39

63.929

100

0.639

  dprA/cilB/dalA Streptococcus pneumoniae R6

63.929

100

0.639

  dprA/cilB/dalA Streptococcus pneumoniae TIGR4

63.929

100

0.639

  dprA/cilB/dalA Streptococcus mitis SK321

63.929

100

0.639

  dprA Lactococcus lactis subsp. cremoris KW2

61.871

99.286

0.614

  dprA Legionella pneumophila strain ERS1305867

42.739

86.071

0.368

  dprA Haemophilus influenzae Rd KW20

38.258

94.286

0.361