Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   RYQ61_RS07880 Genome accession   NZ_CP136799
Coordinates   1556813..1557514 (+) Length   233 a.a.
NCBI ID   WP_003072980.1    Uniprot ID   A0A3R9KV56
Organism   Streptococcus intermedius strain XH2169     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1551813..1562514
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RYQ61_RS07860 (RYQ61_07860) ccpA 1552736..1553740 (+) 1005 WP_020998737.1 catabolite control protein A Regulator
  RYQ61_RS07865 (RYQ61_07865) - 1553833..1554831 (+) 999 WP_003072984.1 glycosyltransferase family 4 protein -
  RYQ61_RS07870 (RYQ61_07870) - 1554833..1556146 (+) 1314 WP_102568207.1 glycosyltransferase family 4 protein -
  RYQ61_RS07875 (RYQ61_07875) - 1556173..1556514 (+) 342 WP_048786749.1 hypothetical protein -
  RYQ61_RS07880 (RYQ61_07880) micA 1556813..1557514 (+) 702 WP_003072980.1 response regulator YycF Regulator
  RYQ61_RS07885 (RYQ61_07885) micB 1557507..1558859 (+) 1353 WP_003072979.1 cell wall metabolism sensor histidine kinase VicK Regulator
  RYQ61_RS07890 (RYQ61_07890) vicX 1558861..1559664 (+) 804 WP_102568206.1 MBL fold metallo-hydrolase Regulator
  RYQ61_RS07895 (RYQ61_07895) - 1559673..1560032 (+) 360 WP_003072977.1 YbaN family protein -
  RYQ61_RS07900 (RYQ61_07900) rnc 1560421..1561119 (+) 699 WP_021002810.1 ribonuclease III -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26851.80 Da        Isoelectric Point: 4.6824

>NTDB_id=892741 RYQ61_RS07880 WP_003072980.1 1556813..1557514(+) (micA) [Streptococcus intermedius strain XH2169]
MKKILVVDDEKPISDIIKFNMVKEGYEVVTAFDGREALELFEAERPDILILDLMLPEIDGLEVARTIRKTSNVPIIVLSA
KDSEFDKVIGLEIGADDYMTKPFSNRELQARVKAILRRTDLTIENQEAEAAPTEIVIGDLQILTDAFVVKKHGEELDLTH
REFELLHHLATHIGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDIPSRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=892741 RYQ61_RS07880 WP_003072980.1 1556813..1557514(+) (micA) [Streptococcus intermedius strain XH2169]
ATGAAAAAAATATTAGTTGTAGATGATGAAAAACCAATCTCAGATATCATAAAATTTAACATGGTAAAAGAAGGTTATGA
GGTAGTGACAGCCTTCGATGGTCGTGAAGCGTTAGAGCTGTTTGAAGCAGAACGTCCAGATATTTTGATTTTGGATTTGA
TGTTGCCTGAAATAGATGGCTTAGAGGTAGCGCGAACGATTCGGAAAACGAGCAATGTACCAATCATCGTTCTGTCGGCT
AAAGATAGCGAATTTGATAAAGTCATTGGTCTCGAAATCGGCGCAGATGATTATATGACAAAGCCGTTTTCTAATCGTGA
GTTACAGGCGCGTGTCAAAGCTATTTTACGTCGTACAGATTTGACAATTGAAAATCAAGAAGCAGAAGCTGCTCCAACAG
AAATTGTGATTGGAGATTTGCAGATTTTGACGGATGCTTTTGTTGTGAAAAAGCATGGTGAAGAATTGGATTTAACACAC
CGTGAATTTGAATTACTACACCACCTAGCTACACATATTGGTCAAGTGATGACGCGTGAACACCTACTAGAAACAGTATG
GGGTTATGATTATTTTGGAGATGTGCGGACTGTTGATGTAACGATTCGCCGTTTGAGGGAAAAAATTGAAGATATTCCTA
GCCGCCCAGAGTATATTTTAACACGGCGTGGTGTTGGATATTATATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(153-228)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A3R9KV56

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

83.262

100

0.833
  vicR Streptococcus mutans UA159

79.237

100

0.803
  covR Streptococcus salivarius strain HSISS4

44.348

98.712

0.438
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.541

98.283

0.438
  scnR Streptococcus mutans UA159

36.052

100

0.361