NTDB

Overview

Name	clpP	Type	Regulator
Locus tag	RW107_RS18345	Genome accession	NZ_CP136257
Coordinates	3537706..3538299 (+)	Length	197 a.a.
NCBI ID	WP_003228214.1	Uniprot ID	A0A199WEF2
Organism	Bacillus subtilis strain A9
Function	degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3532706..3543299

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RW107_RS18315 (RW107_18315)	aspP	3533678..3535240 (+)	1563	WP_003228228.1	aspartate/proton symporter AspP	-
RW107_RS18320 (RW107_18320)	-	3535335..3535919 (+)	585	WP_003244443.1	TetR family transcriptional regulator	-
RW107_RS18325 (RW107_18325)	psmA	3536002..3536337 (+)	336	WP_041850504.1	QacE family quaternary ammonium compound efflux SMR transporter	-
RW107_RS18330 (RW107_18330)	psmB	3536337..3536657 (+)	321	WP_003228222.1	QacE family quaternary ammonium compound efflux SMR transporter	-
RW107_RS18335 (RW107_18335)	yvdQ	3536693..3537205 (-)	513	WP_014478056.1	DUF3231 family protein	-
RW107_RS18345 (RW107_18345)	clpP	3537706..3538299 (+)	594	WP_003228214.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
RW107_RS18350 (RW107_18350)	pgmB	3538344..3539018 (-)	675	WP_041850503.1	beta-phosphoglucomutase	-
RW107_RS18355 (RW107_18355)	malL	3539015..3540700 (-)	1686	WP_041850502.1	oligo-1,6-glucosidase	-
RW107_RS18360 (RW107_18360)	mdxK	3540693..3542966 (-)	2274	WP_041850501.1	maltose phosphorylase	-

Sequence

Protein

Download Length: 197 a.a. Molecular weight: 21682.00 Da Isoelectric Point: 4.9416

                                >NTDB_id=889912 RW107_RS18345 WP_003228214.1 3537706..3538299(+) (clpP) [Bacillus subtilis strain A9]

MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLAAEDPEKEISLYINSPGGSITAGMAIYDT

MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILLLRDKLNKVLAERTGQ

PLEVIERDTDRDNFKSAEEALEYGLIDKILTHTEDKK

Nucleotide

Download Length: 594 bp

                                >NTDB_id=889912 RW107_RS18345 WP_003228214.1 3537706..3538299(+) (clpP) [Bacillus subtilis strain A9]

ATGAATTTAATACCTACAGTCATTGAACAAACGAACCGCGGAGAAAGAGCGTATGACATTTATTCTCGTCTATTAAAGGA

TCGTATCATCATGCTTGGATCTGCGATTGATGACAACGTTGCGAACTCCATCGTGTCACAGCTTTTATTCTTAGCAGCAG

AAGACCCTGAAAAAGAAATTTCTCTTTACATCAACAGCCCGGGCGGCTCTATTACAGCCGGTATGGCGATCTATGATACC

ATGCAGTTTATTAAGCCGAAGGTATCTACAATTTGTATCGGTATGGCTGCGTCAATGGGCGCGTTCCTGCTTGCAGCCGG

CGAAAAAGGCAAACGCTATGCACTTCCAAACAGTGAAGTCATGATTCACCAGCCTCTTGGCGGTGCGCAAGGTCAAGCGA

CAGAAATTGAAATTGCTGCGAAACGCATTCTCTTGCTTCGCGACAAATTAAACAAAGTCCTAGCTGAACGTACTGGCCAG

CCGCTTGAAGTGATCGAACGTGACACAGACCGTGATAACTTCAAGTCTGCTGAAGAAGCGCTTGAATACGGCCTGATTGA

CAAAATTTTGACTCACACAGAAGACAAAAAGTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(13-192)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure
AlphaFold DB	A0A199WEF2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
clpP	Bacillus subtilis subsp. subtilis str. 168	100	100	1
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	68.617	95.431	0.655
clpP	Streptococcus thermophilus LMG 18311	58.163	99.492	0.579
clpP	Streptococcus thermophilus LMD-9	58.163	99.492	0.579
clpP	Streptococcus pneumoniae D39	57.812	97.462	0.563
clpP	Streptococcus pneumoniae Rx1	57.812	97.462	0.563
clpP	Streptococcus pneumoniae R6	57.812	97.462	0.563
clpP	Streptococcus pneumoniae TIGR4	57.812	97.462	0.563
clpP	Lactococcus lactis subsp. cremoris KW2	57.895	96.447	0.558
clpP	Streptococcus pyogenes JRS4	56.122	99.492	0.558
clpP	Streptococcus pyogenes MGAS315	56.122	99.492	0.558
clpP	Streptococcus mutans UA159	54.822	100	0.548
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	55.789	96.447	0.538

Detailed information NTG0889912