Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   RS401_RS13495 Genome accession   NZ_CP135601
Coordinates   2619472..2620053 (-) Length   193 a.a.
NCBI ID   WP_000991625.1    Uniprot ID   A0A2A8KY00
Organism   Bacillus sp. SI2     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 2614472..2625053
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RS401_RS13465 (RS401_13465) - 2614483..2615319 (-) 837 WP_000557584.1 PP2C family serine/threonine-protein phosphatase -
  RS401_RS13470 (RS401_13470) - 2615303..2615790 (-) 488 Protein_2581 HIT family protein -
  RS401_RS13475 (RS401_13475) - 2615897..2616064 (-) 168 WP_002053336.1 hypothetical protein -
  RS401_RS13480 (RS401_13480) - 2616363..2617199 (-) 837 WP_001991533.1 proline/glycine betaine ABC transporter permease -
  RS401_RS13485 (RS401_13485) - 2617192..2618397 (-) 1206 WP_000370609.1 glycine betaine/L-proline ABC transporter ATP-binding protein -
  RS401_RS13490 (RS401_13490) - 2618569..2619426 (+) 858 WP_001991535.1 glycine betaine ABC transporter substrate-binding protein -
  RS401_RS13495 (RS401_13495) clpP 2619472..2620053 (-) 582 WP_000991625.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator
  RS401_RS13500 (RS401_13500) - 2620075..2620761 (-) 687 WP_001991536.1 RNA polymerase subunit sigma-70 -
  RS401_RS13505 (RS401_13505) - 2620905..2621225 (+) 321 WP_001991538.1 2Fe-2S iron-sulfur cluster-binding protein -
  RS401_RS13510 (RS401_13510) rpiA 2621230..2621892 (+) 663 WP_000364536.1 ribose 5-phosphate isomerase A -
  RS401_RS13515 (RS401_13515) - 2622000..2622434 (+) 435 WP_001991541.1 GNAT family N-acetyltransferase -
  RS401_RS13520 (RS401_13520) - 2622565..2623932 (-) 1368 WP_001991542.1 lytic polysaccharide monooxygenase -
  RS401_RS13525 (RS401_13525) - 2624369..2624887 (-) 519 WP_000720566.1 DNA topology modulation protein -

Sequence

Protein


Download         Length: 193 a.a.        Molecular weight: 21178.42 Da        Isoelectric Point: 5.0776

>NTDB_id=887113 RS401_RS13495 WP_000991625.1 2619472..2620053(-) (clpP) [Bacillus sp. SI2]
MNAIPYVVEQTKLGERSYDIYSRLLKDRIVIIGSEINDQVASSVVAQLLFLEAEDAEKDIFLYINSPGGSTTAGFAILDT
MNLIKPDVQTLCMGFAASFGALLLLSGAKGKRFALPNSEIMIHQPLGGAQGQATEIEITAKRILKLKHDINKMIAEKTGQ
PIERVAHDTERDYFMTAEEAKAYGIVDDVVTKK

Nucleotide


Download         Length: 582 bp        

>NTDB_id=887113 RS401_RS13495 WP_000991625.1 2619472..2620053(-) (clpP) [Bacillus sp. SI2]
TTGAATGCAATTCCATATGTTGTAGAACAAACGAAATTAGGAGAACGTTCCTATGATATATATTCAAGGTTATTAAAAGA
CCGTATTGTTATTATCGGTTCAGAAATAAATGATCAAGTAGCGAGTAGTGTCGTAGCTCAATTATTATTTTTAGAAGCAG
AAGATGCAGAGAAAGATATATTTTTATACATTAATAGCCCAGGCGGATCAACGACAGCAGGTTTTGCCATATTAGATACG
ATGAATTTAATCAAACCAGACGTGCAAACGCTATGCATGGGCTTTGCAGCATCATTTGGTGCATTGCTATTATTATCAGG
TGCAAAAGGAAAACGGTTTGCACTCCCAAATAGTGAAATTATGATTCATCAGCCGCTTGGTGGTGCACAAGGGCAAGCGA
CGGAAATTGAAATCACAGCAAAAAGAATTTTAAAGTTAAAACATGATATTAATAAAATGATTGCAGAAAAAACAGGGCAA
CCGATTGAAAGAGTAGCACATGATACAGAAAGAGATTATTTTATGACTGCAGAAGAAGCGAAGGCATATGGGATTGTAGA
TGATGTTGTTACGAAAAAATAG

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(14-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A2A8KY00

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

68.063

98.964

0.674
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

66.667

97.927

0.653
  clpP Streptococcus thermophilus LMD-9

54.688

99.482

0.544
  clpP Streptococcus pneumoniae Rx1

54.688

99.482

0.544
  clpP Streptococcus thermophilus LMG 18311

54.688

99.482

0.544
  clpP Streptococcus pneumoniae D39

54.688

99.482

0.544
  clpP Streptococcus pneumoniae R6

54.688

99.482

0.544
  clpP Streptococcus pneumoniae TIGR4

54.688

99.482

0.544
  clpP Streptococcus pyogenes MGAS315

55.556

97.927

0.544
  clpP Streptococcus pyogenes JRS4

55.556

97.927

0.544
  clpP Streptococcus mutans UA159

53.439

97.927

0.523
  clpP Lactococcus lactis subsp. cremoris KW2

51.852

97.927

0.508
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

49.735

97.927

0.487