Detailed information NTG0886552

Bioinformatically predicted

Overview

• Name: micA
• Type: Regulator
• Locus tag: RRU92_RS06975
• Genome accession: NZ_CP135436
• Coordinates: 1447726..1448430 (+)
• Length: 234 a.a.
• NCBI ID: WP_049508493.1
• Uniprot ID: A0AA96S1K5
• Organism: Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1442726..1453430

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RRU92_RS06955 (RRU92_06955)	-	1443312..1444112 (+)	801	WP_315639093.1	dihydroorotate dehydrogenase electron transfer subunit	-
RRU92_RS06960 (RRU92_06960)	-	1444075..1445061 (+)	987	WP_315639094.1	dihydroorotate dehydrogenase	-
RRU92_RS06965 (RRU92_06965)	-	1445127..1446038 (+)	912	WP_315639095.1	bifunctional riboflavin kinase/FAD synthetase	-
RRU92_RS06970 (RRU92_06970)	mutY	1446498..1447661 (+)	1164	WP_315639096.1	A/G-specific adenine glycosylase	-
RRU92_RS06975 (RRU92_06975)	micA	1447726..1448430 (+)	705	WP_049508493.1	response regulator YycF	Regulator
RRU92_RS06980 (RRU92_06980)	micB	1448423..1449772 (+)	1350	WP_153225530.1	cell wall metabolism sensor histidine kinase VicK	Regulator
RRU92_RS06985 (RRU92_06985)	vicX	1449774..1450583 (+)	810	WP_315639097.1	MBL fold metallo-hydrolase	Regulator
RRU92_RS06990 (RRU92_06990)	-	1450619..1451875 (-)	1257	WP_315639098.1	ISL3 family transposase	-
RRU92_RS06995 (RRU92_06995)	relB	1452096..1452338 (+)	243	WP_248034299.1	type II toxin-antitoxin system RelB family antitoxin	-
RRU92_RS07000 (RRU92_07000)	-	1452340..1452594 (+)	255	WP_315639101.1	type II toxin-antitoxin system RelE/ParE family toxin	-
RRU92_RS07005 (RRU92_07005)	-	1452647..1453420 (+)	774	WP_315639103.1	potassium channel family protein	-

Sequence

Protein

• Length: 234 a.a.
• Molecular weight: 26965.79 Da
• Isoelectric Point: 4.6697

>NTDB_id=886552 RRU92_RS06975 WP_049508493.1 1447726..1448430(+) (micA) [Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006]
MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAEQPDIIILDLMLPEIDGLEVAKTIRKTSSVPIIMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRTDLVSVDNQEPETKLQSLQIGDLEILPDAYVAKKYGEELDLT
HREFELLHHLASHLGQVITREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRNND

Nucleotide

• Length: 705 bp

>NTDB_id=886552 RRU92_RS06975 WP_049508493.1 1447726..1448430(+) (micA) [Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006]
ATGAAAAAAATACTAATTGTAGATGATGAAAAACCCATCTCAGATATTATAAAATTTAATATGACCAAGGAAGGTTATGA
AGTTGTAACTGCTTTTAATGGTCGTGAAGCACTTGAACAATTTGAAGCTGAGCAACCAGATATTATTATCTTGGATTTGA
TGCTTCCAGAGATTGATGGACTTGAGGTCGCAAAAACTATTCGTAAGACAAGTAGTGTTCCTATTATCATGCTTTCAGCA
AAGGATAGCGAATTTGATAAGGTTATTGGGCTTGAGCTTGGGGCGGATGACTATGTAACCAAGCCATTTTCAAATCGTGA
ACTACAGGCTCGTGTTAAAGCTCTTCTCCGTCGTACAGATCTTGTTTCAGTTGATAACCAAGAACCTGAAACGAAATTAC
AAAGTTTGCAGATTGGCGATTTGGAGATTTTACCAGATGCCTACGTGGCTAAGAAATATGGTGAAGAGTTAGATTTAACC
CACCGTGAATTCGAACTCTTGCATCATTTAGCTTCTCATCTTGGACAAGTTATTACCCGAGAACATCTTCTTGAAACCGT
TTGGGGATATGACTATTTTGGGGATGTCCGTACAGTAGATGTAACCATTCGACGCTTGCGTGAGAAGATTGAAGATACAC
CAAGCAGACCTGAATACATCCTAACTCGTCGTGGAGTAGGATATTATATGAGAAATAATGATTGA

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (154-229)

• Response regulator receiver domain (Response_reg) (4-112)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
micA	Streptococcus pneumoniae Cp1015	92.704	99.573	0.923
vicR	Streptococcus mutans UA159	78.723	100	0.791
covR	Streptococcus salivarius strain HSISS4	44.348	98.291	0.436
covR	Lactococcus lactis subsp. lactis strain DGCC12653	43.913	98.291	0.432
scnR	Streptococcus mutans UA159	37.5	99.145	0.372