Detailed information NTG0886553

Bioinformatically predicted

Overview

• Name: micB
• Type: Regulator
• Locus tag: RRU92_RS06980
• Genome accession: NZ_CP135436
• Coordinates: 1448423..1449772 (+)
• Length: 449 a.a.
• NCBI ID: WP_153225530.1
• Uniprot ID: A0AA96S2K8
• Organism: Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006
• Function: repress competence development (predicted from homology) Competence regulation

Related MGE

Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type	MGE coordinates	Gene coordinates	Relative position	Distance (bp)
IS/Tn	1450619..1451875	1448423..1449772	flank	847

Gene organization within MGE regions

Location: 1448423..1451875

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RRU92_RS06980 (RRU92_06980)	micB	1448423..1449772 (+)	1350	WP_153225530.1	cell wall metabolism sensor histidine kinase VicK	Regulator
RRU92_RS06985 (RRU92_06985)	vicX	1449774..1450583 (+)	810	WP_315639097.1	MBL fold metallo-hydrolase	Regulator
RRU92_RS06990 (RRU92_06990)	-	1450619..1451875 (-)	1257	WP_315639098.1	ISL3 family transposase	-

Sequence

Protein

• Length: 449 a.a.
• Molecular weight: 51735.14 Da
• Isoelectric Point: 4.6159

>NTDB_id=886553 RRU92_RS06980 WP_153225530.1 1448423..1449772(+) (micB) [Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006]
MIEVIRQTILTSDFIFILILIGFILLVSFLLLESRRDNIRLRQINQKIKDLIDGDYSQVLDMQGSSEITNITNNLNDLSE
VIRLTQENLEQESKRLHSILSYMTDGVLATNRRGQIIMINDMAKRQLGVERDDALNQNILELLKIEEEYELRELITQSPE
LMIYSQNLNGEYISLRVRFALIRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
EPVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATSHLDVELINFTAFITFILNRFDKMKSQDEEKKYELVRDYPITSVW
IEIDTDKMTQVIDNILNNAIKYSPDGGKITVNMKTTDDQMILSISDQGLGIPKEDLPKIFDRFYRVDKARSRAQGGTGLG
LAIAKEIIKQHKGFIWAKSEYGKGSTFTIVLPYDNDAVKEEIWEDELED

Nucleotide

• Length: 1350 bp

>NTDB_id=886553 RRU92_RS06980 WP_153225530.1 1448423..1449772(+) (micB) [Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006]
ATGATTGAAGTAATTAGACAAACAATTTTGACGAGCGACTTTATCTTTATCCTCATCTTAATTGGCTTTATTCTGTTAGT
GTCTTTTCTCTTGCTTGAGAGTCGTCGTGATAATATTCGTTTGAGGCAGATCAATCAGAAAATAAAAGATTTGATTGATG
GTGATTATTCTCAGGTTTTGGATATGCAGGGAAGCTCAGAGATAACTAATATCACTAACAATCTTAATGATTTGTCTGAA
GTCATTCGTCTGACTCAAGAAAATCTGGAACAAGAGAGTAAAAGGTTGCATAGTATCCTGTCCTACATGACAGATGGAGT
GCTTGCAACCAACCGTCGTGGGCAAATCATCATGATCAATGATATGGCCAAGAGACAACTTGGAGTTGAAAGGGATGATG
CTCTTAATCAAAATATCTTAGAGTTACTCAAGATTGAAGAAGAGTATGAGCTGAGAGAACTTATTACTCAGAGCCCTGAG
CTGATGATTTATTCGCAGAATCTTAATGGCGAATATATCAGTTTGCGCGTTCGTTTTGCCTTGATTCGTAGAGAGTCTGG
CTTTATCTCTGGTTTAGTAGCAGTTCTACATGATACGACTGAACAAGAGAAGGAAGAACGTGAGAGAAGGCTTTTCGTTT
CGAACGTTAGTCATGAGTTGCGTACCCCTTTGACAAGTGTAAAATCCTATTTGGAGGCCTTGGACGAAGGAGCGCTGACA
GAACCAGTTGCTCCAGATTTTATCAAGGTTTCTTTGGATGAAACCAACCGTATGATGCGGATGGTGACGGATCTCTTGCA
TCTATCACGGATTGACAACGCAACTAGTCACTTAGATGTTGAATTGATTAACTTTACGGCCTTTATCACCTTTATCCTTA
ATCGTTTTGATAAAATGAAAAGTCAAGATGAGGAGAAGAAGTACGAGTTGGTGAGAGACTATCCGATTACTTCTGTTTGG
ATTGAGATTGATACAGATAAGATGACCCAGGTGATTGACAATATCCTGAATAACGCTATCAAGTATTCACCAGATGGTGG
AAAAATCACTGTTAACATGAAAACTACAGATGATCAGATGATTTTATCTATTTCAGATCAAGGACTTGGGATTCCTAAAG
AAGATTTACCAAAGATTTTTGACCGTTTTTATAGGGTTGATAAGGCTAGAAGTCGTGCTCAAGGAGGAACAGGACTAGGA
TTGGCTATCGCCAAGGAAATCATCAAGCAACATAAGGGATTTATCTGGGCTAAGAGTGAGTATGGCAAGGGATCTACCTT
TACTATCGTACTTCCATACGATAATGATGCCGTGAAAGAAGAGATTTGGGAGGATGAACTAGAAGACTAG

Domains

Predicted by InterproScan.

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

• PAS fold (PAS) (95-198)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (324-434)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
micB	Streptococcus pneumoniae Cp1015	87.244	97.773	0.853
vicK	Streptococcus mutans UA159	71.29	91.537	0.653