Detailed information    

insolico Bioinformatically predicted

Overview

Name   comEA/celA/cilE   Type   Machinery gene
Locus tag   RRU92_RS06160 Genome accession   NZ_CP135436
Coordinates   1279178..1279819 (+) Length   213 a.a.
NCBI ID   WP_049549324.1    Uniprot ID   A0A1E8TYN9
Organism   Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006     
Function   dsDNA binding to the cell surface (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 1274178..1284819
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RRU92_RS06145 (RRU92_06145) ald 1276474..1277586 (-) 1113 WP_315638976.1 alanine dehydrogenase -
  RRU92_RS06150 (RRU92_06150) - 1277766..1278380 (+) 615 WP_315638977.1 hypothetical protein -
  RRU92_RS06155 (RRU92_06155) - 1278543..1279112 (+) 570 WP_049549323.1 GNAT family N-acetyltransferase -
  RRU92_RS06160 (RRU92_06160) comEA/celA/cilE 1279178..1279819 (+) 642 WP_049549324.1 helix-hairpin-helix domain-containing protein Machinery gene
  RRU92_RS06165 (RRU92_06165) comEC/celB 1279803..1282013 (+) 2211 WP_315638978.1 ComEC/Rec2 family competence protein Machinery gene
  RRU92_RS06170 (RRU92_06170) - 1282139..1283425 (+) 1287 WP_000169115.1 peptidase U32 family protein -
  RRU92_RS06175 (RRU92_06175) - 1283439..1283750 (+) 312 WP_315638979.1 CHY zinc finger protein -
  RRU92_RS06180 (RRU92_06180) - 1283979..1284179 (+) 201 WP_001054552.1 F0F1 ATP synthase subunit C -

Sequence

Protein


Download         Length: 213 a.a.        Molecular weight: 23100.23 Da        Isoelectric Point: 5.0508

>NTDB_id=886548 RRU92_RS06160 WP_049549324.1 1279178..1279819(+) (comEA/celA/cilE) [Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006]
MEELIEKIQEYKIIVICAGLGLVLGGFFLLKPVAQAPAKETKVQTEVTAVPKDSTDEKEDGNQKEEVVGQDLITVDVKGA
VKSPGIYDLPVGSRINDAVQKAGGLTDNADSKSINLAQRISDEALVYVPTKEEATSQEAYSNASNTKENKKVNLNKASIE
ELKQVKGLGVKRAQDIIDHRDSNGKFKSVDELKKVSGIGAKTIEKLKEYVTVD

Nucleotide


Download         Length: 642 bp        

>NTDB_id=886548 RRU92_RS06160 WP_049549324.1 1279178..1279819(+) (comEA/celA/cilE) [Streptococcus sp. DTU_2020_1001019_1_SI_AUS_MUR_006]
ATGGAAGAACTTATTGAGAAAATCCAAGAATATAAAATCATTGTTATCTGTGCTGGTTTGGGCTTGGTCTTAGGCGGATT
TTTCCTGCTAAAGCCAGTCGCTCAAGCACCTGCTAAGGAAACAAAGGTGCAGACTGAAGTTACAGCTGTTCCAAAGGATT
CGACGGATGAAAAGGAAGATGGAAATCAGAAGGAAGAAGTGGTGGGGCAAGATCTGATTACTGTCGATGTCAAAGGTGCT
GTCAAATCACCTGGAATTTATGATTTACCAGTTGGAAGTCGTATCAATGATGCTGTTCAAAAAGCTGGTGGATTGACAGA
TAATGCTGATAGTAAGTCTATCAATCTTGCTCAGAGAATTAGTGATGAAGCACTTGTTTATGTCCCGACTAAGGAAGAAG
CTACAAGCCAAGAGGCATATTCAAATGCTTCCAACACCAAAGAAAATAAGAAAGTCAACCTTAATAAAGCCAGTATAGAG
GAACTGAAGCAAGTCAAAGGTTTAGGTGTTAAACGTGCTCAAGATATTATCGACCATCGTGATTCCAACGGTAAGTTTAA
GTCAGTTGATGAGCTCAAAAAGGTTTCTGGTATTGGTGCAAAAACGATAGAAAAGTTAAAAGAGTATGTTACAGTGGATT
AG

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(75-124)

Helix-hairpin-helix motif (HHH_3)

(149-211)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A1E8TYN9

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comEA/celA/cilE Streptococcus mitis NCTC 12261

77.315

100

0.784
  comEA/celA/cilE Streptococcus pneumoniae TIGR4

76.852

100

0.779
  comEA/celA/cilE Streptococcus pneumoniae Rx1

75.463

100

0.765
  comEA/celA/cilE Streptococcus pneumoniae R6

75.463

100

0.765
  comEA/celA/cilE Streptococcus pneumoniae D39

75.463

100

0.765
  comEA/celA/cilE Streptococcus mitis SK321

75.463

100

0.765
  comEA Streptococcus thermophilus LMD-9

36.207

100

0.394
  comEA Lactococcus lactis subsp. cremoris KW2

36.444

100

0.385