Detailed information    

insolico Bioinformatically predicted

Overview

Name   prx   Type   Regulator
Locus tag   MGAS38289_RS05000 Genome accession   NZ_CP151440
Coordinates   1001354..1001542 (-) Length   62 a.a.
NCBI ID   WP_011285559.1    Uniprot ID   -
Organism   Streptococcus pyogenes strain MGAS38289     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Genomic Context

Location: 996354..1006542
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  MGAS38289_RS04975 (MGAS38289_02050) - 998158..998529 (+) 372 WP_010922377.1 GntR family transcriptional regulator -
  MGAS38289_RS04980 (MGAS38289_02052) - 998529..999227 (+) 699 WP_002984437.1 ABC transporter ATP-binding protein -
  MGAS38289_RS04985 (MGAS38289_02054) - 999237..1000022 (+) 786 WP_010922378.1 hypothetical protein -
  MGAS38289_RS04990 (MGAS38289_02056) - 1000149..1000763 (-) 615 WP_011285558.1 TVP38/TMEM64 family protein -
  MGAS38289_RS05000 (MGAS38289_02060) prx 1001354..1001542 (-) 189 WP_011285559.1 hypothetical protein Regulator
  MGAS38289_RS05005 (MGAS38289_02062) speA 1001762..1002517 (+) 756 WP_011285560.1 streptococcal pyrogenic exotoxin SpeA -
  MGAS38289_RS05010 (MGAS38289_02064) - 1002639..1003298 (-) 660 WP_009880240.1 hypothetical protein -
  MGAS38289_RS05015 (MGAS38289_02066) - 1003298..1003519 (-) 222 WP_009880241.1 hypothetical protein -
  MGAS38289_RS05020 (MGAS38289_02068) - 1003529..1004302 (-) 774 WP_011054795.1 hypothetical protein -
  MGAS38289_RS05025 (MGAS38289_02070) - 1004313..1004915 (-) 603 WP_011054796.1 hypothetical protein -
  MGAS38289_RS05030 (MGAS38289_02072) - 1004927..1005691 (-) 765 WP_011285561.1 CHAP domain-containing protein -
  MGAS38289_RS05035 (MGAS38289_02074) - 1005693..1006025 (-) 333 WP_011285562.1 phage holin -
  MGAS38289_RS05040 (MGAS38289_02076) - 1006025..1006348 (-) 324 WP_015055952.1 hypothetical protein -
  MGAS38289_RS05045 (MGAS38289_02078) - 1006362..1006484 (-) 123 WP_015055953.1 hypothetical protein -

Sequence

Protein


Download         Length: 62 a.a.        Molecular weight: 7290.41 Da        Isoelectric Point: 4.3313

>NTDB_id=885451 MGAS38289_RS05000 WP_011285559.1 1001354..1001542(-) (prx) [Streptococcus pyogenes strain MGAS38289]
MLYIDEFKEAIDKGYILGDTVAIVRKNGKIFDYVLPHEKVRDDEVVTVERVEEVMVELDYIK

Nucleotide


Download         Length: 189 bp        

>NTDB_id=885451 MGAS38289_RS05000 WP_011285559.1 1001354..1001542(-) (prx) [Streptococcus pyogenes strain MGAS38289]
ATGTTATATATAGATGAGTTTAAAGAAGCGATTGATAAGGGGTATATTTTAGGTGACACAGTAGCGATAGTGCGTAAAAA
CGGAAAGATATTTGATTATGTGTTACCACACGAAAAAGTGAGAGATGATGAAGTTGTGACGGTAGAGAGAGTGGAAGAAG
TGATGGTGGAATTAGACTATATCAAATGA

Domains


No domain identified.



Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS315

100

95.161

0.952
  prx Streptococcus pyogenes MGAS315

79.032

100

0.79
  prx Streptococcus pyogenes MGAS8232

76.271

95.161

0.726
  prx Streptococcus pyogenes MGAS315

76.271

95.161

0.726
  prx Streptococcus pyogenes MGAS315

74.576

95.161

0.71
  prx Streptococcus pyogenes MGAS315

69.492

95.161

0.661
  prx Streptococcus pyogenes MGAS315

82.927

66.129

0.548