Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   RMP65_RS07065 Genome accession   NZ_CP135089
Coordinates   1435628..1436332 (-) Length   234 a.a.
NCBI ID   WP_004298854.1    Uniprot ID   A0A0K2E6P6
Organism   Streptococcus suis strain ID34567     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1430628..1441332
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RMP65_RS07050 (RMP65_07050) vga(F) 1431833..1433218 (-) 1386 WP_014637680.1 ABC-F type ribosomal protection protein Vga(F) -
  RMP65_RS07055 (RMP65_07055) vicX 1433476..1434279 (-) 804 WP_024399908.1 MBL fold metallo-hydrolase Regulator
  RMP65_RS07060 (RMP65_07060) micB 1434286..1435635 (-) 1350 WP_002935841.1 cell wall metabolism sensor histidine kinase VicK Regulator
  RMP65_RS07065 (RMP65_07065) micA 1435628..1436332 (-) 705 WP_004298854.1 response regulator YycF Regulator
  RMP65_RS07070 (RMP65_07070) - 1436526..1437287 (+) 762 WP_024407012.1 amino acid ABC transporter ATP-binding protein -
  RMP65_RS07075 (RMP65_07075) - 1437298..1438137 (+) 840 WP_313681060.1 transporter substrate-binding domain-containing protein -
  RMP65_RS07080 (RMP65_07080) - 1438152..1438850 (+) 699 WP_013730248.1 amino acid ABC transporter permease -
  RMP65_RS07085 (RMP65_07085) - 1438865..1439524 (+) 660 WP_024402697.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26781.77 Da        Isoelectric Point: 4.8957

>NTDB_id=884940 RMP65_RS07065 WP_004298854.1 1435628..1436332(-) (micA) [Streptococcus suis strain ID34567]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFEAEFPDIVILDLMLPELDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQTNIESTGTPELVIGDLVILPDAFVAKKHGKELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYFIKGND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=884940 RMP65_RS07065 WP_004298854.1 1435628..1436332(-) (micA) [Streptococcus suis strain ID34567]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATTAAGTTTAATATGACGCGTGAGGGATATGA
AGTTGTGACAGCTTTCGATGGACGTGAAGCCTTGGAAGTATTTGAGGCTGAGTTTCCTGACATTGTCATTTTGGACTTGA
TGCTGCCAGAATTGGACGGACTAGAGGTCGCTCGAACGATTCGTAAGACCAGCAATGTTCCAATCTTGATGTTATCTGCT
AAAGATAGCGAATTTGATAAGGTTATCGGGCTTGAAATCGGGGCGGATGATTATGTGACCAAGCCCTTCTCTAATCGCGA
ATTGCAGGCGCGTGTTAAGGCTCTTCTTCGTCGTAGTGAATTGGCAGAAACGCAGACAAATATTGAGTCAACAGGAACTC
CAGAGTTGGTGATTGGCGATTTGGTCATTCTGCCTGATGCGTTTGTCGCTAAGAAGCATGGCAAAGAGCTGGAGCTGACC
CATCGTGAGTTTGAATTGCTCCACCATCTGGCCAAACACTTAGGTCAGGTTATGACTCGAGAACATCTATTGGAAACAGT
TTGGGGTTATGATTACTTTGGTGATGTCCGCACGGTGGATGTAACGATTCGTCGTCTGCGTGAGAAAATTGAAGATACAC
CAAGCAGACCAGAATACATTCTTACTCGTCGCGGAGTGGGATATTTTATAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0K2E6P6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.974

99.573

0.816
  vicR Streptococcus mutans UA159

80.426

100

0.808
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.783

98.291

0.44
  covR Streptococcus salivarius strain HSISS4

43.723

98.718

0.432
  scnR Streptococcus mutans UA159

38.095

98.718

0.376