Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   RMP65_RS07060 Genome accession   NZ_CP135089
Coordinates   1434286..1435635 (-) Length   449 a.a.
NCBI ID   WP_002935841.1    Uniprot ID   G7SGQ2
Organism   Streptococcus suis strain ID34567     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1429286..1440635
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RMP65_RS07045 (RMP65_07045) pbp2b 1429672..1431741 (-) 2070 WP_313681058.1 penicillin-binding protein PBP2B -
  RMP65_RS07050 (RMP65_07050) vga(F) 1431833..1433218 (-) 1386 WP_014637680.1 ABC-F type ribosomal protection protein Vga(F) -
  RMP65_RS07055 (RMP65_07055) vicX 1433476..1434279 (-) 804 WP_024399908.1 MBL fold metallo-hydrolase Regulator
  RMP65_RS07060 (RMP65_07060) micB 1434286..1435635 (-) 1350 WP_002935841.1 cell wall metabolism sensor histidine kinase VicK Regulator
  RMP65_RS07065 (RMP65_07065) micA 1435628..1436332 (-) 705 WP_004298854.1 response regulator YycF Regulator
  RMP65_RS07070 (RMP65_07070) - 1436526..1437287 (+) 762 WP_024407012.1 amino acid ABC transporter ATP-binding protein -
  RMP65_RS07075 (RMP65_07075) - 1437298..1438137 (+) 840 WP_313681060.1 transporter substrate-binding domain-containing protein -
  RMP65_RS07080 (RMP65_07080) - 1438152..1438850 (+) 699 WP_013730248.1 amino acid ABC transporter permease -
  RMP65_RS07085 (RMP65_07085) - 1438865..1439524 (+) 660 WP_024402697.1 amino acid ABC transporter permease -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51039.08 Da        Isoelectric Point: 4.5202

>NTDB_id=884939 RMP65_RS07060 WP_002935841.1 1434286..1435635(-) (micB) [Streptococcus suis strain ID34567]
MINQLRYLMTTAEFWFVVILIGFLIALTVLLIENYRDNKQIKQLNQKVNALIEGNYADVLDMRGSPEITDMANSLNDLSE
VIRLTHDNLEQEKTRLTSILSYMSDGVIATDRIGRIIMINDMAQKQLGLSSQKQEQYHLLEVLDLSDRYTLRDLLAQTPE
IVIDHTNENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGQIDVELINFTAFVTFILNRFDQMKNADSDKVYTIVRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGTITFSMKTTDSQLIVSVSDEGLGIPKADLPRIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYSKDIALDEWDDSDEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=884939 RMP65_RS07060 WP_002935841.1 1434286..1435635(-) (micB) [Streptococcus suis strain ID34567]
ATGATTAATCAATTACGTTATTTAATGACCACGGCAGAATTTTGGTTTGTTGTCATTTTGATTGGCTTTCTAATTGCTCT
GACGGTCCTTTTGATTGAAAACTATCGGGATAATAAGCAAATTAAACAACTCAATCAAAAAGTCAATGCCTTAATTGAGG
GGAATTATGCAGATGTGTTAGACATGAGGGGAAGTCCTGAAATCACAGACATGGCGAATTCTCTTAATGATCTGTCGGAG
GTCATCCGCTTAACTCATGATAATTTAGAACAAGAAAAGACACGTCTGACTTCCATCCTGTCCTATATGAGTGACGGTGT
TATTGCTACAGACCGTATCGGACGGATTATCATGATTAACGATATGGCCCAGAAACAGTTGGGGCTTTCTAGCCAAAAGC
AGGAGCAATATCACCTGCTAGAGGTTTTAGATTTATCAGATCGTTACACATTGAGAGATTTGTTGGCTCAGACACCTGAG
ATTGTGATTGATCACACCAATGAAAACGAAGAATTTTTGACTTTACGCGCTAATTTTGCAACGATTCGTAGTGAGAGTGG
TCTGATTTCTGGCTTGGTTGTAGTCTTACATGATATGACCGAGCAGGCCAAGGAAGAACGGGAACGTAGGCTTTTTGTGT
CAAATGTGAGTCATGAATTGCGTACGCCATTGACTTCCGTCAAATCCTATCTAGAGGCTCTGGATGAGGGAGCGCTGACG
GAGTCTGTTGCACCGAGTTTTGTTAAGGTATCCTTAGATGAGACCAACCGCATGATGCGGATGATTACAGACCTCCTAAG
TTTATCGCGTATTGATAATCAAGTTGGTCAGATAGATGTCGAACTGATAAACTTTACTGCTTTTGTGACCTTTATTCTTA
ACCGTTTTGACCAAATGAAAAATGCTGATTCTGATAAGGTCTATACGATTGTTCGTGACTATCAAATCAGTCCTATTTGG
GTTGAGATTGATACAGATAAGATGACTCAGGTTTTGGATAATATCTTAAATAATGCCATTAAATATTCGCCAGATGGCGG
GACAATTACCTTCAGCATGAAGACCACAGATAGCCAGTTGATTGTGTCCGTCTCAGACGAAGGTCTGGGGATTCCGAAAG
CAGATTTACCTAGAATTTTTGACCGATTCTATCGCGTGGACAAGGCACGATCTCGTGCCCAAGGTGGTACAGGTCTTGGT
TTAGCTATTGCAAAAGAAATCGTAAAACAACATAAGGGCTTTATCTGGGCTAAAAGCGAATATGGTCATGGCTCAACGTT
TACAATTGTCTTGCCGTACAGCAAGGACATCGCACTAGATGAGTGGGATGATTCAGATGAGGAAGAATAG

Domains

Predicted by InterproScan.

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)

PAS fold (PAS)

(96-199)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB G7SGQ2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

70.183

97.105

0.682
  vicK Streptococcus mutans UA159

70.72

89.755

0.635