Detailed information
Bioinformatically predicted
Overview
| Name | prx | Type | Regulator |
| Locus tag | QN282_RS03015 | Genome accession | NZ_CP134689 |
| Coordinates | 541514..541702 (+) | Length | 62 a.a. |
| NCBI ID | WP_000027835.1 | Uniprot ID | A0AAV3JNT7 |
| Organism | Streptococcus agalactiae strain HU05/19 | ||
| Function | Inhibit ComR activation (predicted from homology) Competence regulation |
||
Related MGE
Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.
Gene-MGE association summary
| MGE type | MGE coordinates | Gene coordinates | Relative position | Distance (bp) |
|---|---|---|---|---|
| ICE | 531866..589909 | 541514..541702 | within | 0 |
| IS/Tn | 540447..541058 | 541514..541702 | flank | 456 |
Gene organization within MGE regions
Location: 531866..589909
| Locus tag | Gene name | Coordinates (strand) | Size (bp) | Protein ID | Product | Description |
|---|---|---|---|---|---|---|
| QN282_RS02965 (QN282_02955) | - | 532283..532549 (-) | 267 | WP_001872365.1 | hypothetical protein | - |
| QN282_RS02970 (QN282_02960) | - | 532555..533932 (+) | 1378 | Protein_534 | IS3 family transposase | - |
| QN282_RS02975 (QN282_02965) | - | 534105..534268 (-) | 164 | Protein_535 | TM2 domain-containing protein | - |
| QN282_RS02980 (QN282_02970) | - | 535010..536287 (+) | 1278 | WP_000594360.1 | ABC transporter permease | - |
| QN282_RS02985 (QN282_02975) | - | 536297..536953 (+) | 657 | WP_000353149.1 | ABC transporter ATP-binding protein | - |
| QN282_RS02990 (QN282_02980) | - | 536953..538329 (+) | 1377 | WP_000594351.1 | ABC transporter permease | - |
| QN282_RS02995 (QN282_02985) | - | 538426..539079 (+) | 654 | WP_000699093.1 | response regulator transcription factor | - |
| QN282_RS03000 (QN282_02990) | - | 539076..540395 (+) | 1320 | WP_000734169.1 | sensor histidine kinase | - |
| QN282_RS03005 (QN282_02995) | - | 540447..541094 (-) | 648 | Protein_541 | IS3 family transposase | - |
| QN282_RS03010 (QN282_03000) | - | 541272..541472 (+) | 201 | WP_000076708.1 | CsbD family protein | - |
| QN282_RS03015 (QN282_03005) | prx | 541514..541702 (+) | 189 | WP_000027835.1 | hypothetical protein | Regulator |
| QN282_RS03020 (QN282_03010) | - | 542127..543332 (+) | 1206 | WP_000078931.1 | FtsW/RodA/SpoVE family cell cycle protein | - |
| QN282_RS03025 (QN282_03015) | - | 543451..544011 (+) | 561 | WP_001106189.1 | HAD-IA family hydrolase | - |
| QN282_RS03030 (QN282_03020) | gyrB | 544012..545964 (+) | 1953 | WP_000134196.1 | DNA topoisomerase (ATP-hydrolyzing) subunit B | - |
| QN282_RS03035 (QN282_03025) | ezrA | 546058..547782 (+) | 1725 | WP_000094341.1 | septation ring formation regulator EzrA | - |
| QN282_RS03040 (QN282_03030) | serB | 547876..548517 (+) | 642 | WP_000589685.1 | phosphoserine phosphatase SerB | - |
| QN282_RS03045 (QN282_03035) | - | 548538..549023 (-) | 486 | WP_000409124.1 | NUDIX hydrolase | - |
| QN282_RS03050 (QN282_03040) | - | 549036..549491 (-) | 456 | WP_000137373.1 | YueI family protein | - |
| QN282_RS03055 (QN282_03045) | eno | 549689..550996 (+) | 1308 | WP_000022832.1 | surface-displayed alpha-enolase | - |
| QN282_RS03060 (QN282_03050) | - | 551104..552168 (-) | 1065 | WP_000823934.1 | DNA/RNA non-specific endonuclease | - |
| QN282_RS03065 (QN282_03055) | aroA | 552397..553680 (+) | 1284 | WP_000772014.1 | 3-phosphoshikimate 1-carboxyvinyltransferase | - |
| QN282_RS03070 (QN282_03060) | - | 553673..554185 (+) | 513 | WP_001127193.1 | shikimate kinase | - |
| QN282_RS03075 (QN282_03065) | - | 554242..555615 (+) | 1374 | WP_000089337.1 | LCP family protein | - |
| QN282_RS03080 (QN282_03070) | rlmD | 555716..557347 (+) | 1632 | WP_410531128.1 | 23S rRNA (uracil(1939)-C(5))-methyltransferase RlmD | - |
| QN282_RS03085 (QN282_03075) | - | 557366..557647 (+) | 282 | WP_410531129.1 | CD1845 family protein | - |
| QN282_RS03090 (QN282_03080) | - | 557738..558508 (+) | 771 | WP_155961752.1 | replication initiator protein A | - |
| QN282_RS03095 (QN282_03085) | - | 558505..559379 (+) | 875 | Protein_559 | ATP-binding protein | - |
| QN282_RS03100 (QN282_03090) | - | 559376..559861 (+) | 486 | WP_055328033.1 | PcfB family protein | - |
| QN282_RS03105 (QN282_03095) | - | 559858..560901 (+) | 1044 | WP_410531130.1 | type IV secretory system conjugative DNA transfer family protein | - |
| QN282_RS03110 (QN282_03100) | - | 560941..562779 (+) | 1839 | WP_001243448.1 | recombinase family protein | - |
| QN282_RS03115 (QN282_03105) | - | 562855..563427 (+) | 573 | WP_000079884.1 | TetR/AcrR family transcriptional regulator | - |
| QN282_RS03120 (QN282_03110) | - | 563478..563996 (+) | 519 | WP_000708365.1 | ClbS/DfsB family four-helix bundle protein | - |
| QN282_RS03125 (QN282_03115) | - | 564137..565876 (+) | 1740 | WP_001114256.1 | ABC transporter ATP-binding protein | - |
| QN282_RS03130 (QN282_03120) | - | 565869..567578 (+) | 1710 | WP_000488162.1 | ABC transporter ATP-binding protein | - |
| QN282_RS03135 (QN282_03125) | - | 567581..569098 (+) | 1518 | WP_000601967.1 | ABC transporter ATP-binding protein | - |
| QN282_RS03140 (QN282_03130) | - | 569088..569792 (+) | 705 | WP_000567178.1 | energy-coupling factor transporter transmembrane component T | - |
| QN282_RS03145 (QN282_03135) | - | 569803..570387 (+) | 585 | WP_000791750.1 | MptD family putative ECF transporter S component | - |
| QN282_RS03150 (QN282_03140) | - | 570653..571069 (+) | 417 | WP_001074478.1 | sigma factor-like helix-turn-helix DNA-binding protein | - |
| QN282_RS03155 (QN282_03145) | - | 571154..571483 (+) | 330 | WP_000712033.1 | DUF3847 domain-containing protein | - |
| QN282_RS03160 (QN282_03150) | mobQ | 571728..573380 (+) | 1653 | WP_000852174.1 | MobQ family relaxase | - |
| QN282_RS03165 (QN282_03155) | - | 573383..574135 (+) | 753 | WP_004830091.1 | phage replisome organizer N-terminal domain-containing protein | - |
| QN282_RS03170 (QN282_03160) | - | 574309..574632 (+) | 324 | WP_004830093.1 | hypothetical protein | - |
| QN282_RS03175 (QN282_03165) | - | 574654..575661 (+) | 1008 | WP_000797009.1 | ORF6N domain-containing protein | - |
| QN282_RS03180 (QN282_03170) | - | 575771..575956 (+) | 186 | WP_001005000.1 | transposon-encoded TnpW family protein | - |
| QN282_RS03185 (QN282_03175) | - | 575968..576780 (+) | 813 | Protein_577 | VirD4-like conjugal transfer protein, CD1115 family | - |
| QN282_RS03190 (QN282_03180) | - | 576941..577252 (+) | 312 | WP_338176108.1 | single-stranded DNA-binding protein | - |
| QN282_RS03195 (QN282_03185) | - | 577256..577471 (+) | 216 | WP_000394208.1 | Maff2 family mobile element protein | - |
| QN282_RS03200 (QN282_03190) | - | 577491..578354 (+) | 864 | WP_000466901.1 | VirB6/TrbL-like conjugal transfer protein, CD1112 family | - |
| QN282_RS03205 (QN282_03195) | - | 578372..578635 (+) | 264 | WP_001042374.1 | hypothetical protein | - |
| QN282_RS03210 (QN282_03200) | - | 578639..579028 (+) | 390 | WP_000332197.1 | PrgI family protein | - |
| QN282_RS03215 (QN282_03205) | - | 578940..581369 (+) | 2430 | WP_410531131.1 | VirB4-like conjugal transfer ATPase, CD1110 family | - |
| QN282_RS03220 (QN282_03210) | - | 581374..583527 (+) | 2154 | WP_410531132.1 | CD1108 family mobile element protein | - |
| QN282_RS03225 (QN282_03215) | - | 583540..583776 (+) | 237 | WP_047200382.1 | hypothetical protein | - |
| QN282_RS03230 (QN282_03220) | - | 583754..585940 (+) | 2187 | WP_410531133.1 | CD1107 family mobile element protein | - |
| QN282_RS03235 (QN282_03225) | - | 586038..587744 (+) | 1707 | WP_410531134.1 | DNA topoisomerase 3 | - |
| QN282_RS03240 (QN282_03230) | - | 587826..589361 (+) | 1536 | WP_001176344.1 | helix-turn-helix domain-containing protein | - |
Sequence
Protein
Download Length: 62 a.a. Molecular weight: 7180.25 Da Isoelectric Point: 4.7815
>NTDB_id=882805 QN282_RS03015 WP_000027835.1 541514..541702(+) (prx) [Streptococcus agalactiae strain HU05/19]
MSIRTDIDEFKEAIDKGYISGNTVAIVRKNGKIFDYVLLHEEVREEEVVTVERVLDVLRKLS
MSIRTDIDEFKEAIDKGYISGNTVAIVRKNGKIFDYVLLHEEVREEEVVTVERVLDVLRKLS
Nucleotide
Download Length: 189 bp
>NTDB_id=882805 QN282_RS03015 WP_000027835.1 541514..541702(+) (prx) [Streptococcus agalactiae strain HU05/19]
TTGTCTATCAGAACAGATATAGATGAGTTTAAAGAAGCGATTGATAAAGGCTATATTTCAGGGAACACAGTAGCGATAGT
GCGTAAAAACGGAAAGATATTTGATTATGTGTTACTACACGAAGAAGTGAGAGAAGAAGAGGTTGTTACAGTTGAGAGAG
TGCTTGATGTACTGAGGAAGTTATCATAA
TTGTCTATCAGAACAGATATAGATGAGTTTAAAGAAGCGATTGATAAAGGCTATATTTCAGGGAACACAGTAGCGATAGT
GCGTAAAAACGGAAAGATATTTGATTATGTGTTACTACACGAAGAAGTGAGAGAAGAAGAGGTTGTTACAGTTGAGAGAG
TGCTTGATGTACTGAGGAAGTTATCATAA
Domains
No domain identified.
3D structure
| Source | ID | Structure |
|---|
Similar proteins
Only experimentally validated proteins are listed.
| Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
|---|---|---|---|---|
| prx | Streptococcus pyogenes MGAS315 |
72.222 |
87.097 |
0.629 |
| prx | Streptococcus pyogenes MGAS8232 |
69.091 |
88.71 |
0.613 |
| prx | Streptococcus pyogenes MGAS315 |
66.667 |
87.097 |
0.581 |
| prx | Streptococcus pyogenes MGAS315 |
85 |
64.516 |
0.548 |
| prx | Streptococcus pyogenes MGAS315 |
61.818 |
88.71 |
0.548 |
| prx | Streptococcus pyogenes MGAS315 |
74.359 |
62.903 |
0.468 |
| prx | Streptococcus pyogenes MGAS315 |
78.378 |
59.677 |
0.468 |