Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   RJW55_RS03575 Genome accession   NZ_CP134473
Coordinates   744756..745460 (+) Length   234 a.a.
NCBI ID   WP_004298854.1    Uniprot ID   A0A0K2E6P6
Organism   Streptococcus suis strain TMW_SS028     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 739756..750460
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RJW55_RS03555 (RJW55_03555) - 741564..742223 (-) 660 WP_172073111.1 amino acid ABC transporter permease -
  RJW55_RS03560 (RJW55_03560) - 742238..742936 (-) 699 WP_024391257.1 amino acid ABC transporter permease -
  RJW55_RS03565 (RJW55_03565) - 742951..743790 (-) 840 WP_043027112.1 transporter substrate-binding domain-containing protein -
  RJW55_RS03570 (RJW55_03570) - 743801..744562 (-) 762 WP_002935839.1 amino acid ABC transporter ATP-binding protein -
  RJW55_RS03575 (RJW55_03575) micA 744756..745460 (+) 705 WP_004298854.1 response regulator YycF Regulator
  RJW55_RS03580 (RJW55_03580) micB 745453..746802 (+) 1350 WP_024379730.1 cell wall metabolism sensor histidine kinase VicK Regulator
  RJW55_RS03585 (RJW55_03585) vicX 746809..747612 (+) 804 WP_043027113.1 MBL fold metallo-hydrolase Regulator
  RJW55_RS03590 (RJW55_03590) - 748140..748781 (+) 642 WP_228475326.1 ATP-binding cassette domain-containing protein -
  RJW55_RS03595 (RJW55_03595) - 748944..749678 (+) 735 WP_043027114.1 ATP-binding cassette domain-containing protein -

Sequence

Protein


Download         Length: 234 a.a.        Molecular weight: 26781.77 Da        Isoelectric Point: 4.8957

>NTDB_id=880160 RJW55_RS03575 WP_004298854.1 744756..745460(+) (micA) [Streptococcus suis strain TMW_SS028]
MKKILIVDDEKPISDIIKFNMTREGYEVVTAFDGREALEVFEAEFPDIVILDLMLPELDGLEVARTIRKTSNVPILMLSA
KDSEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSELAETQTNIESTGTPELVIGDLVILPDAFVAKKHGKELELT
HREFELLHHLAKHLGQVMTREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYFIKGND

Nucleotide


Download         Length: 705 bp        

>NTDB_id=880160 RJW55_RS03575 WP_004298854.1 744756..745460(+) (micA) [Streptococcus suis strain TMW_SS028]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCAGATATTATTAAGTTTAATATGACTCGTGAGGGATATGA
AGTTGTGACAGCTTTCGATGGACGTGAAGCCTTGGAAGTGTTTGAGGCTGAGTTTCCTGACATTGTCATTTTGGACTTGA
TGTTGCCAGAATTGGACGGACTAGAGGTCGCTCGAACGATTCGTAAGACCAGCAATGTTCCAATCTTGATGTTATCTGCT
AAAGATAGCGAATTTGATAAGGTTATCGGGCTTGAAATAGGGGCGGATGATTATGTGACCAAACCCTTCTCTAATCGCGA
ATTGCAGGCGCGTGTTAAGGCTCTTCTTCGTCGTAGTGAATTGGCAGAGACGCAGACAAATATTGAGTCAACAGGAACTC
CAGAGTTGGTGATTGGCGATTTGGTCATTCTGCCTGATGCGTTTGTCGCTAAGAAGCATGGCAAAGAGCTGGAGCTGACC
CATCGTGAGTTTGAATTGCTCCACCATCTGGCCAAACACTTAGGTCAGGTTATGACTCGAGAACATCTATTGGAAACAGT
TTGGGGTTATGATTACTTTGGTGATGTCCGCACGGTGGATGTAACGATTCGTCGTCTGCGTGAGAAAATTGAAGATACAC
CAAGCCGACCAGAATATATTCTTACTCGTCGCGGAGTGGGATATTTTATAAAAGGAAATGATTAA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-229)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0K2E6P6

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

81.974

99.573

0.816
  vicR Streptococcus mutans UA159

80.426

100

0.808
  covR Lactococcus lactis subsp. lactis strain DGCC12653

44.783

98.291

0.44
  covR Streptococcus salivarius strain HSISS4

43.723

98.718

0.432
  scnR Streptococcus mutans UA159

38.095

98.718

0.376