Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   RJW55_RS03580 Genome accession   NZ_CP134473
Coordinates   745453..746802 (+) Length   449 a.a.
NCBI ID   WP_024379730.1    Uniprot ID   A0A0Z8J8V5
Organism   Streptococcus suis strain TMW_SS028     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 740453..751802
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RJW55_RS03555 (RJW55_03555) - 741564..742223 (-) 660 WP_172073111.1 amino acid ABC transporter permease -
  RJW55_RS03560 (RJW55_03560) - 742238..742936 (-) 699 WP_024391257.1 amino acid ABC transporter permease -
  RJW55_RS03565 (RJW55_03565) - 742951..743790 (-) 840 WP_043027112.1 transporter substrate-binding domain-containing protein -
  RJW55_RS03570 (RJW55_03570) - 743801..744562 (-) 762 WP_002935839.1 amino acid ABC transporter ATP-binding protein -
  RJW55_RS03575 (RJW55_03575) micA 744756..745460 (+) 705 WP_004298854.1 response regulator YycF Regulator
  RJW55_RS03580 (RJW55_03580) micB 745453..746802 (+) 1350 WP_024379730.1 cell wall metabolism sensor histidine kinase VicK Regulator
  RJW55_RS03585 (RJW55_03585) vicX 746809..747612 (+) 804 WP_043027113.1 MBL fold metallo-hydrolase Regulator
  RJW55_RS03590 (RJW55_03590) - 748140..748781 (+) 642 WP_228475326.1 ATP-binding cassette domain-containing protein -
  RJW55_RS03595 (RJW55_03595) - 748944..749678 (+) 735 WP_043027114.1 ATP-binding cassette domain-containing protein -

Sequence

Protein


Download         Length: 449 a.a.        Molecular weight: 51035.09 Da        Isoelectric Point: 4.5202

>NTDB_id=880161 RJW55_RS03580 WP_024379730.1 745453..746802(+) (micB) [Streptococcus suis strain TMW_SS028]
MINQLRYLMTTAEFWFVVILIGFLIALTVLLIENYRDNKQIKQLNQKVNALIEGNYADVLDMRGSPEITDMANSLNDLSE
VIRLTHDNLEQEKTRLTSILSYMSDGVIATDRIGRIIMINDMAQKQLGLSNPKQEQYHLLEVLDLSDRYTLRDLLAQTPE
IVIDHTNENEEFLTLRANFATIRSESGLISGLVVVLHDMTEQAKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALT
ESVAPSFVKVSLDETNRMMRMITDLLSLSRIDNQVGQIDVELINFTAFVTFILNRFDQMKNADSDKVYTIVRDYQISPIW
VEIDTDKMTQVLDNILNNAIKYSPDGGTITFSMKTTDSQLIVSVSDEGLGIPKADLPRIFDRFYRVDKARSRAQGGTGLG
LAIAKEIVKQHKGFIWAKSEYGHGSTFTIVLPYSKDIALDEWDDSDEEE

Nucleotide


Download         Length: 1350 bp        

>NTDB_id=880161 RJW55_RS03580 WP_024379730.1 745453..746802(+) (micB) [Streptococcus suis strain TMW_SS028]
ATGATTAATCAATTACGTTATTTAATGACCACGGCAGAATTTTGGTTTGTTGTCATTTTGATTGGCTTTCTAATTGCTCT
AACGGTCCTTTTGATTGAGAACTATCGGGATAATAAGCAAATTAAACAACTCAATCAAAAAGTCAATGCCTTAATTGAGG
GGAATTATGCAGATGTGTTAGACATGAGGGGAAGTCCTGAAATAACAGATATGGCTAATTCCCTCAATGATTTGTCCGAG
GTTATCCGCTTAACTCACGATAATTTAGAACAAGAAAAGACGCGTCTGACTTCCATCCTGTCCTATATGAGTGACGGTGT
TATTGCTACAGACCGTATCGGACGGATCATCATGATTAACGATATGGCCCAGAAACAGTTGGGGTTATCTAACCCAAAGC
AGGAGCAGTATCACCTGCTCGAGGTTTTAGATTTATCAGACCGTTATACATTGAGAGATTTGTTGGCTCAGACACCTGAG
ATTGTGATTGATCACACCAATGAAAACGAAGAATTTTTGACTTTACGCGCTAATTTTGCCACGATTCGTAGTGAGAGTGG
CCTGATTTCTGGCTTGGTTGTCGTCTTGCATGATATGACCGAGCAGGCCAAGGAAGAACGGGAACGTAGGCTGTTTGTTT
CAAATGTGAGTCATGAATTGCGTACGCCATTGACTTCCGTTAAATCCTATCTAGAGGCTCTGGATGAGGGAGCGCTGACG
GAGTCTGTTGCACCGAGTTTTGTCAAGGTATCCTTAGATGAGACCAACCGCATGATGCGGATGATTACAGACCTCCTTAG
CTTATCGCGTATTGATAATCAAGTTGGTCAGATAGATGTTGAACTGATAAACTTTACTGCTTTTGTGACCTTTATTCTTA
ACCGTTTTGACCAAATGAAAAATGCTGATTCTGATAAGGTCTATACGATTGTTCGTGACTATCAAATCAGTCCTATTTGG
GTTGAGATTGATACAGATAAGATGACTCAGGTTTTAGATAATATCTTAAATAATGCCATTAAATATTCGCCAGACGGCGG
GACAATTACCTTCAGCATGAAGACCACAGATAGCCAGTTGATTGTATCCGTCTCAGACGAAGGTCTGGGGATTCCGAAAG
CAGATTTACCTAGAATTTTTGACCGATTTTATCGCGTAGACAAGGCACGATCTCGTGCCCAAGGTGGTACAGGTCTTGGT
TTAGCTATTGCAAAAGAAATCGTGAAACAACATAAGGGCTTTATCTGGGCTAAAAGCGAATATGGTCATGGATCAACGTT
TACAATTGTCTTGCCGTACAGCAAGGACATCGCACTGGATGAGTGGGATGATTCAGATGAGGAAGAATAG

Domains

Predicted by InterproScan.

PAS fold (PAS)

(96-199)

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A0Z8J8V5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

70.183

97.105

0.682
  vicK Streptococcus mutans UA159

70.72

89.755

0.635