Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   RIN70_RS07290 Genome accession   NZ_CP134147
Coordinates   1440356..1441057 (-) Length   233 a.a.
NCBI ID   WP_003008151.1    Uniprot ID   -
Organism   Streptococcus parasanguinis strain 30.8.10     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1435356..1446057
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RIN70_RS07265 (RIN70_07265) - 1435571..1436620 (-) 1050 WP_313790506.1 hypothetical protein -
  RIN70_RS07270 (RIN70_07270) - 1436716..1437375 (-) 660 WP_313790507.1 DUF443 family protein -
  RIN70_RS07275 (RIN70_07275) - 1437525..1438052 (-) 528 WP_313790508.1 hypothetical protein -
  RIN70_RS07280 (RIN70_07280) vicX 1438194..1439003 (-) 810 WP_049475139.1 MBL fold metallo-hydrolase Regulator
  RIN70_RS07285 (RIN70_07285) micB 1439011..1440363 (-) 1353 WP_049497363.1 cell wall metabolism sensor histidine kinase VicK Regulator
  RIN70_RS07290 (RIN70_07290) micA 1440356..1441057 (-) 702 WP_003008151.1 response regulator YycF Regulator
  RIN70_RS07295 (RIN70_07295) - 1441942..1442991 (+) 1050 WP_195623466.1 DUF389 domain-containing protein -
  RIN70_RS07300 (RIN70_07300) thrS 1443203..1445146 (-) 1944 WP_195623467.1 threonine--tRNA ligase -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26690.49 Da        Isoelectric Point: 4.6027

>NTDB_id=878879 RIN70_RS07290 WP_003008151.1 1440356..1441057(-) (micA) [Streptococcus parasanguinis strain 30.8.10]
MKKILVVDDEKPISDIIKFNMAKEGYEVLTAFDGREALEVFAAENPDIIILDLMLPEIDGLEVARTIRKTSNVPIIVLSA
KDTEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSEFAADPQLENEADTEIVIGDLHILPDAFLVQKGNKELDLTH
REFELLYHLATHVGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPGRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=878879 RIN70_RS07290 WP_003008151.1 1440356..1441057(-) (micA) [Streptococcus parasanguinis strain 30.8.10]
ATGAAAAAAATATTAGTAGTTGATGATGAAAAACCAATTTCAGATATTATCAAATTTAACATGGCAAAAGAGGGCTATGA
AGTCTTGACAGCCTTTGATGGCCGGGAAGCTTTGGAAGTCTTTGCGGCTGAGAATCCGGATATTATTATTCTAGATTTGA
TGTTGCCAGAGATTGATGGTCTGGAAGTGGCGCGTACCATTCGCAAGACCAGCAATGTGCCCATCATTGTCCTTTCTGCC
AAAGATACAGAATTTGATAAGGTTATCGGACTTGAAATTGGTGCGGATGACTATGTGACCAAACCCTTCTCTAATCGGGA
ATTGCAAGCGCGTGTGAAGGCCTTGTTGCGTCGTTCGGAGTTTGCGGCTGATCCTCAGCTTGAAAATGAGGCCGATACGG
AAATTGTCATTGGTGATCTTCACATTCTTCCAGATGCCTTCTTGGTTCAAAAAGGCAACAAAGAATTGGACTTGACCCAT
CGTGAGTTTGAATTGCTCTATCACCTTGCGACCCATGTCGGTCAAGTGATGACCCGTGAACACCTTCTTGAGACGGTGTG
GGGCTATGATTACTTTGGTGATGTTCGGACAGTGGACGTGACGGTTCGTCGTTTGCGTGAAAAAATCGAGGACACACCAG
GACGTCCAGAATATATCTTGACCCGCCGTGGTGTCGGATATTATATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-228)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

82.403

100

0.824
  vicR Streptococcus mutans UA159

78.298

100

0.79
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

98.712

0.455
  covR Streptococcus salivarius strain HSISS4

43.668

98.283

0.429
  scnR Streptococcus mutans UA159

36.957

98.712

0.365