Detailed information    

insolico Bioinformatically predicted

Overview

Name   micA   Type   Regulator
Locus tag   RDV49_RS05090 Genome accession   NZ_CP133988
Coordinates   1078263..1078964 (+) Length   233 a.a.
NCBI ID   WP_003008151.1    Uniprot ID   -
Organism   Streptococcus parasanguinis strain B-1756     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1073263..1083964
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RDV49_RS05080 (RDV49_05080) thrS 1074171..1076114 (+) 1944 WP_003008158.1 threonine--tRNA ligase -
  RDV49_RS05085 (RDV49_05085) - 1076326..1077375 (-) 1050 WP_003008156.1 DUF389 domain-containing protein -
  RDV49_RS05090 (RDV49_05090) micA 1078263..1078964 (+) 702 WP_003008151.1 response regulator YycF Regulator
  RDV49_RS05095 (RDV49_05095) micB 1078957..1080309 (+) 1353 WP_003008150.1 cell wall metabolism sensor histidine kinase VicK Regulator
  RDV49_RS05100 (RDV49_05100) vicX 1080317..1081126 (+) 810 WP_023918725.1 MBL fold metallo-hydrolase Regulator
  RDV49_RS05105 (RDV49_05105) - 1081269..1081814 (+) 546 WP_003008145.1 hypothetical protein -
  RDV49_RS05110 (RDV49_05110) - 1081848..1082234 (+) 387 WP_003008142.1 YbaN family protein -
  RDV49_RS05115 (RDV49_05115) rnc 1082334..1083035 (+) 702 WP_037607998.1 ribonuclease III -

Sequence

Protein


Download         Length: 233 a.a.        Molecular weight: 26690.49 Da        Isoelectric Point: 4.6027

>NTDB_id=878164 RDV49_RS05090 WP_003008151.1 1078263..1078964(+) (micA) [Streptococcus parasanguinis strain B-1756]
MKKILVVDDEKPISDIIKFNMAKEGYEVLTAFDGREALEVFAAENPDIIILDLMLPEIDGLEVARTIRKTSNVPIIVLSA
KDTEFDKVIGLEIGADDYVTKPFSNRELQARVKALLRRSEFAADPQLENEADTEIVIGDLHILPDAFLVQKGNKELDLTH
REFELLYHLATHVGQVMTREHLLETVWGYDYFGDVRTVDVTVRRLREKIEDTPGRPEYILTRRGVGYYMRNND

Nucleotide


Download         Length: 702 bp        

>NTDB_id=878164 RDV49_RS05090 WP_003008151.1 1078263..1078964(+) (micA) [Streptococcus parasanguinis strain B-1756]
ATGAAAAAAATATTAGTAGTTGATGATGAAAAACCAATTTCAGATATTATCAAATTTAACATGGCAAAAGAGGGCTATGA
AGTCTTGACAGCCTTTGATGGCCGGGAAGCTTTGGAAGTCTTTGCGGCTGAGAATCCGGATATTATTATTCTAGATTTGA
TGTTGCCAGAGATTGATGGTCTGGAAGTGGCGCGTACCATTCGCAAGACCAGCAATGTGCCCATCATTGTCCTTTCTGCC
AAAGATACAGAATTTGATAAGGTTATCGGACTTGAAATTGGTGCTGATGACTATGTGACCAAACCCTTCTCTAATCGGGA
ATTGCAAGCGCGTGTGAAGGCCTTGTTGCGTCGTTCGGAGTTTGCGGCTGATCCTCAGCTTGAAAATGAGGCCGATACGG
AAATTGTCATTGGTGATCTTCACATTCTTCCAGATGCCTTCTTGGTTCAAAAAGGCAACAAAGAATTGGACTTGACCCAT
CGTGAGTTTGAATTGCTCTATCACCTTGCGACCCATGTCGGTCAAGTGATGACCCGTGAACACCTTCTTGAGACGGTGTG
GGGCTATGATTACTTTGGTGATGTTCGGACAGTGGACGTGACAGTTCGTCGTTTGCGTGAAAAAATCGAGGACACACCGG
GACGTCCAGAATATATCTTGACCCGCCGTGGTGTCGGATATTATATGAGAAACAATGATTGA

Domains

Predicted by InterproScan.

Transcriptional regulatory protein, C terminal (Trans_reg_C)

(154-228)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micA Streptococcus pneumoniae Cp1015

82.403

100

0.824
  vicR Streptococcus mutans UA159

78.298

100

0.79
  covR Lactococcus lactis subsp. lactis strain DGCC12653

46.087

98.712

0.455
  covR Streptococcus salivarius strain HSISS4

43.668

98.283

0.429
  scnR Streptococcus mutans UA159

36.957

98.712

0.365