Detailed information NTG0878165

Bioinformatically predicted

Overview

• Name: micB
• Type: Regulator
• Locus tag: RDV49_RS05095
• Genome accession: NZ_CP133988
• Coordinates: 1078957..1080309 (+)
• Length: 450 a.a.
• NCBI ID: WP_003008150.1
• Uniprot ID: A0AAX4AUI5
• Organism: Streptococcus parasanguinis strain B-1756
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1073957..1085309

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RDV49_RS05080 (RDV49_05080)	thrS	1074171..1076114 (+)	1944	WP_003008158.1	threonine--tRNA ligase	-
RDV49_RS05085 (RDV49_05085)	-	1076326..1077375 (-)	1050	WP_003008156.1	DUF389 domain-containing protein	-
RDV49_RS05090 (RDV49_05090)	micA	1078263..1078964 (+)	702	WP_003008151.1	response regulator YycF	Regulator
RDV49_RS05095 (RDV49_05095)	micB	1078957..1080309 (+)	1353	WP_003008150.1	cell wall metabolism sensor histidine kinase VicK	Regulator
RDV49_RS05100 (RDV49_05100)	vicX	1080317..1081126 (+)	810	WP_023918725.1	MBL fold metallo-hydrolase	Regulator
RDV49_RS05105 (RDV49_05105)	-	1081269..1081814 (+)	546	WP_003008145.1	hypothetical protein	-
RDV49_RS05110 (RDV49_05110)	-	1081848..1082234 (+)	387	WP_003008142.1	YbaN family protein	-
RDV49_RS05115 (RDV49_05115)	rnc	1082334..1083035 (+)	702	WP_037607998.1	ribonuclease III	-

Sequence

Protein

• Length: 450 a.a.
• Molecular weight: 51101.28 Da
• Isoelectric Point: 4.5621

>NTDB_id=878165 RDV49_RS05095 WP_003008150.1 1078957..1080309(+) (micB) [Streptococcus parasanguinis strain B-1756]
MIDQLKQFVMSSNFVFVLITVGFIIVVALLLLENRRDNIKLRQLNAKIKDLIAGDYSEVVDMQGSPELTDMTNSINDLSE
VIRLTHENLEQETKRLTSILSYMTDGVLATNRRGQIIMVNEMAAKQLNVNPDEVLNTSILDLLSLGDDYDLRSLITEVPE
LTIDSQDENGEYISLRVRFALIRRESGFISGLVAVLHDTTEQDKEERERRLFVSNVSHELRTPLTSVKSYLEALDDGALS
EPVAPDFVKVSLNETNRMMRMVTDLLSLSRIDNETSQLDIELTNFTAFITFILNRFDKIKSQSQEDTKKYELIREYPITP
IWVEIDTDKMTQVIDNILNNAIKYSPDGGKIKVGMKTTDAQLIISISDEGLGIPKKDLPRIFDRFYRVDKARSRAQGGTG
LGLAIAKEIVKQHKGFIWAKSEYGKGSTFTIVLPYDKDAIKDDWDTEEEE

Nucleotide

• Length: 1353 bp

>NTDB_id=878165 RDV49_RS05095 WP_003008150.1 1078957..1080309(+) (micB) [Streptococcus parasanguinis strain B-1756]
ATGATTGATCAACTAAAACAATTTGTCATGTCGTCGAACTTTGTCTTTGTTCTGATTACGGTTGGGTTTATCATTGTGGT
AGCCTTGCTTTTGCTAGAAAACCGTAGGGACAATATCAAGCTCAGACAATTAAACGCCAAAATTAAGGATCTGATTGCAG
GGGACTATTCCGAAGTGGTCGACATGCAAGGAAGTCCAGAACTGACGGATATGACCAATAGTATCAATGATCTGTCGGAG
GTTATTCGCCTGACGCATGAAAACTTGGAACAAGAAACCAAGCGTTTGACCAGTATCCTTTCTTATATGACAGATGGGGT
GCTTGCGACCAACAGACGCGGTCAGATCATCATGGTCAATGAAATGGCAGCCAAGCAATTGAATGTTAATCCAGATGAGG
TGCTCAATACCAGTATTCTGGATTTGCTTTCGCTTGGAGATGACTATGATCTGCGAAGCTTGATTACAGAAGTACCAGAG
TTGACCATCGATTCCCAGGATGAAAATGGGGAATACATAAGTCTTCGTGTGCGCTTTGCCTTGATTCGTCGCGAGTCAGG
TTTTATCTCTGGTCTGGTAGCTGTCTTGCACGATACGACGGAGCAGGACAAGGAAGAGCGGGAACGTCGCCTCTTTGTCT
CCAATGTGAGTCATGAATTACGGACACCTTTGACCAGTGTGAAATCCTATCTAGAAGCCCTGGACGATGGCGCTTTGTCA
GAGCCGGTAGCACCAGATTTTGTCAAGGTTTCGCTCAATGAAACCAACCGCATGATGCGCATGGTCACAGATCTATTGAG
CTTGTCACGAATCGATAATGAAACCAGTCAGTTGGACATCGAGTTGACCAACTTTACGGCCTTTATCACCTTTATTTTGA
ACCGGTTTGATAAGATCAAGAGTCAATCGCAAGAAGATACCAAGAAGTATGAACTGATCCGGGAATACCCGATCACCCCG
ATCTGGGTTGAAATTGATACGGATAAAATGACCCAGGTGATCGACAATATCTTGAACAATGCCATCAAGTACTCACCTGA
TGGTGGAAAAATCAAGGTAGGGATGAAAACGACGGATGCCCAGTTGATTATTTCCATTTCAGATGAGGGCTTGGGAATTC
CCAAGAAAGACTTGCCACGCATTTTTGATCGCTTTTACCGAGTGGATAAGGCGCGTAGCCGGGCCCAAGGTGGGACTGGT
CTAGGCTTAGCCATTGCTAAGGAGATCGTTAAGCAACACAAGGGCTTTATTTGGGCCAAGAGTGAATATGGCAAGGGATC
TACTTTTACCATTGTCTTGCCGTACGACAAAGATGCTATTAAAGACGACTGGGATACAGAAGAGGAAGAATAA

Domains

Predicted by InterproScan.

• PAS fold (PAS) (96-198)

• Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c) (326-436)

• His Kinase A (phospho-acceptor) domain (HisKA) (209-273)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
micB	Streptococcus pneumoniae Cp1015	78.685	98	0.771
vicK	Streptococcus mutans UA159	71.499	90.444	0.647