Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   RDV49_RS04775 Genome accession   NZ_CP133988
Coordinates   1012787..1013377 (+) Length   196 a.a.
NCBI ID   WP_003008286.1    Uniprot ID   I2NKQ0
Organism   Streptococcus parasanguinis strain B-1756     
Function   degradation of ComX; degradation of ComW (predicted from homology)   
Competence regulation

Genomic Context

Location: 1007787..1018377
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RDV49_RS04765 (RDV49_04765) mgtA 1009149..1011809 (+) 2661 WP_003008289.1 magnesium-translocating P-type ATPase -
  RDV49_RS04770 (RDV49_04770) upp 1012029..1012658 (+) 630 WP_003005574.1 uracil phosphoribosyltransferase -
  RDV49_RS04775 (RDV49_04775) clpP 1012787..1013377 (+) 591 WP_003008286.1 ATP-dependent Clp protease proteolytic subunit Regulator
  RDV49_RS04780 (RDV49_04780) - 1013655..1013933 (+) 279 WP_003008284.1 DUF2129 domain-containing protein -
  RDV49_RS04785 (RDV49_04785) - 1014042..1015199 (+) 1158 WP_003008282.1 ABC transporter substrate-binding protein -
  RDV49_RS04790 (RDV49_04790) - 1015281..1016150 (+) 870 WP_037608024.1 branched-chain amino acid ABC transporter permease -
  RDV49_RS04795 (RDV49_04795) - 1016154..1017101 (+) 948 WP_003008278.1 branched-chain amino acid ABC transporter permease -
  RDV49_RS04800 (RDV49_04800) - 1017101..1017865 (+) 765 WP_003005595.1 ABC transporter ATP-binding protein -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 21498.54 Da        Isoelectric Point: 4.5101

>NTDB_id=878162 RDV49_RS04775 WP_003008286.1 1012787..1013377(+) (clpP) [Streptococcus parasanguinis strain B-1756]
MIPVVIEQTSRGERSYDIYSRLLKDRIIMVTGPVEDQMANSIIAQLLFLDAQDNTKDIYMYINTPGGSVSAGLAIVDTMN
FIKSDVQTIVMGMAASMGTIIASSGAKGKRFMLPNAEYMIHQPMGGTGGGTQQTDMAIAAEHLLKTRNNLEKILAENSGQ
SIEKVHADAERDNWMSAQETLEYGFIDEIMANNKLD

Nucleotide


Download         Length: 591 bp        

>NTDB_id=878162 RDV49_RS04775 WP_003008286.1 1012787..1013377(+) (clpP) [Streptococcus parasanguinis strain B-1756]
ATGATTCCAGTAGTTATTGAACAAACCAGTCGTGGAGAACGTTCTTACGATATTTATTCCCGTCTGTTGAAAGATCGAAT
TATCATGGTAACAGGACCAGTTGAGGACCAAATGGCTAACTCCATTATCGCTCAATTGCTCTTCTTGGATGCCCAAGATA
ATACAAAAGATATCTATATGTATATCAATACACCAGGTGGCTCTGTCTCGGCAGGTCTAGCCATTGTAGATACCATGAAC
TTTATCAAGTCAGATGTCCAAACCATTGTCATGGGGATGGCAGCTTCTATGGGAACAATTATCGCTTCAAGCGGCGCGAA
GGGCAAACGCTTCATGTTGCCAAACGCCGAGTATATGATTCACCAACCAATGGGTGGTACTGGTGGTGGTACCCAACAAA
CCGATATGGCGATTGCAGCAGAACACTTGCTCAAAACACGGAATAACTTGGAAAAAATCCTTGCGGAAAATTCAGGTCAA
TCCATTGAAAAAGTGCATGCTGATGCTGAACGTGACAATTGGATGAGCGCGCAAGAAACACTTGAATATGGCTTTATTGA
TGAAATCATGGCCAATAATAAATTGGACTAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(11-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB I2NKQ0

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Streptococcus pneumoniae Rx1

93.878

100

0.939
  clpP Streptococcus pneumoniae D39

93.878

100

0.939
  clpP Streptococcus pneumoniae R6

93.878

100

0.939
  clpP Streptococcus pneumoniae TIGR4

93.878

100

0.939
  clpP Streptococcus thermophilus LMG 18311

93.846

99.49

0.934
  clpP Streptococcus thermophilus LMD-9

93.846

99.49

0.934
  clpP Streptococcus pyogenes JRS4

88.205

99.49

0.878
  clpP Streptococcus pyogenes MGAS315

88.205

99.49

0.878
  clpP Streptococcus mutans UA159

87.692

99.49

0.872
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

85.128

99.49

0.847
  clpP Lactococcus lactis subsp. cremoris KW2

84.615

99.49

0.842
  clpP Bacillus subtilis subsp. subtilis str. 168

57.732

98.98

0.571
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

58.031

98.469

0.571