Detailed information    

insolico Bioinformatically predicted

Overview

Name   htrA   Type   Regulator
Locus tag   RDV49_RS02445 Genome accession   NZ_CP133988
Coordinates   473572..474753 (-) Length   393 a.a.
NCBI ID   WP_003009234.1    Uniprot ID   -
Organism   Streptococcus parasanguinis strain B-1756     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 468572..479753
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RDV49_RS02420 (RDV49_02420) - 469080..469577 (+) 498 WP_037608180.1 DUF1307 domain-containing protein -
  RDV49_RS02425 (RDV49_02425) - 469613..469804 (-) 192 WP_003002008.1 DUF951 domain-containing protein -
  RDV49_RS02430 (RDV49_02430) dnaN 469817..470953 (-) 1137 WP_021154169.1 DNA polymerase III subunit beta -
  RDV49_RS02435 (RDV49_02435) dnaA 471113..472471 (-) 1359 WP_003009237.1 chromosomal replication initiator protein DnaA -
  RDV49_RS02440 (RDV49_02440) spo0J 472739..473500 (-) 762 WP_003009236.1 ParB/RepB/Spo0J family partition protein Regulator
  RDV49_RS02445 (RDV49_02445) htrA 473572..474753 (-) 1182 WP_003009234.1 S1C family serine protease Regulator
  RDV49_RS02450 (RDV49_02450) rlmH 474958..475437 (+) 480 WP_003009233.1 23S rRNA (pseudouridine(1915)-N(3))-methyltransferase RlmH -
  RDV49_RS02460 (RDV49_02460) - 475898..477238 (+) 1341 WP_003009231.1 GHKL domain-containing protein -
  RDV49_RS02465 (RDV49_02465) comE/comE2 477235..477993 (+) 759 WP_003009229.1 response regulator transcription factor Regulator

Sequence

Protein


Download         Length: 393 a.a.        Molecular weight: 41746.89 Da        Isoelectric Point: 5.7871

>NTDB_id=878154 RDV49_RS02445 WP_003009234.1 473572..474753(-) (htrA) [Streptococcus parasanguinis strain B-1756]
MKSSSNLLKKLGNITLIFVVGFLGGILGTFLTLQTSHSSTSNTESKQVHSTTVKTAYKNTTSTSEAVDKVKNAVVSVITY
SDSSNQGLFEKEENSDSQISSEGSGVIYKKEGKYAYLVTNTHVINGAKKVDILLADGNKVPGEVVGSDVYSDIAVVRISA
DKAKAVAEFGDSNQLTVGETAIAIGSPLGTDYANSVTQGIISSQGRNVKLKADNGQNISTRALQTDAAINPGNSGGPLIN
IQGQVIGITSSKISNNGQTSVEGMGFAIPANDVVNIIKQLEEKGKVVRPALGIQMMDLSNLSTSDLSQLKLPEKISGGVL
VRSTLENMPASDKLQRYDVITKIDDTDIESTADLQSALYSHQINDTIKVIFYRDGKQQTTSIKLTKSTEDLSD

Nucleotide


Download         Length: 1182 bp        

>NTDB_id=878154 RDV49_RS02445 WP_003009234.1 473572..474753(-) (htrA) [Streptococcus parasanguinis strain B-1756]
ATGAAATCTTCATCTAATTTACTGAAAAAACTTGGAAACATAACCCTCATTTTCGTTGTAGGTTTTCTAGGTGGGATTCT
TGGAACCTTTTTAACCTTACAAACCTCTCATTCTTCTACTTCAAATACTGAAAGTAAGCAAGTACACTCAACCACTGTTA
AAACAGCTTATAAAAATACAACCTCAACTAGTGAGGCCGTAGATAAGGTGAAAAATGCTGTGGTTTCTGTGATTACTTAT
TCTGATTCTTCGAATCAAGGGTTATTTGAAAAAGAAGAAAACTCTGACTCACAAATTTCTAGTGAAGGTTCTGGAGTCAT
TTATAAAAAAGAAGGAAAATATGCCTACCTTGTTACCAACACCCATGTAATCAATGGTGCTAAAAAAGTAGATATTCTTT
TAGCAGATGGGAATAAAGTCCCTGGAGAAGTAGTTGGATCAGATGTCTATTCTGATATTGCAGTCGTTCGCATTAGTGCG
GATAAAGCAAAGGCAGTAGCTGAATTCGGAGATTCAAACCAATTAACAGTCGGTGAGACTGCAATTGCAATTGGTAGCCC
TCTTGGAACAGATTATGCGAATTCTGTTACCCAAGGGATTATTTCCAGCCAAGGCCGCAATGTGAAATTGAAAGCCGATA
ATGGACAAAATATCTCTACACGCGCCTTACAAACAGACGCAGCCATCAACCCAGGAAACTCTGGAGGTCCATTAATCAAT
ATTCAAGGACAAGTCATCGGGATTACCTCAAGTAAAATTTCAAATAACGGACAAACTTCAGTAGAAGGAATGGGATTTGC
AATTCCTGCAAATGATGTTGTCAATATTATCAAGCAACTAGAAGAAAAAGGAAAAGTAGTTCGACCAGCTCTTGGAATCC
AAATGATGGATTTATCCAACCTTTCAACATCTGATTTAAGCCAATTAAAACTTCCTGAAAAAATCTCTGGAGGAGTACTG
GTTCGTTCAACACTTGAAAATATGCCTGCTTCAGATAAATTGCAACGCTATGATGTTATCACAAAGATCGATGATACAGA
TATCGAGTCAACGGCAGATTTACAATCCGCCCTCTATTCTCACCAAATCAATGATACGATCAAGGTCATATTCTATCGTG
ATGGAAAACAACAAACAACTTCTATCAAGTTGACAAAATCAACTGAGGATCTGAGCGATTAA

Domains

Predicted by InterproScan.

Trypsin-like peptidase domain (Trypsin_2)

(103-248)

PDZ domain (PDZ_2)

(289-384)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  htrA Streptococcus gordonii str. Challis substr. CH1

67.839

100

0.687
  htrA Streptococcus mitis NCTC 12261

63.104

100

0.631
  htrA Streptococcus pneumoniae Rx1

63.104

100

0.631
  htrA Streptococcus pneumoniae D39

63.104

100

0.631
  htrA Streptococcus pneumoniae R6

63.104

100

0.631
  htrA Streptococcus pneumoniae TIGR4

63.104

100

0.631
  htrA Streptococcus mutans UA159

53.766

97.964

0.527