Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   RF668_RS00085 Genome accession   NZ_CP133787
Coordinates   15839..16438 (+) Length   199 a.a.
NCBI ID   WP_011834647.1    Uniprot ID   A0A166TF89
Organism   Lactococcus cremoris strain KCKM 0438     
Function   degradation of ComX (predicted from homology)   
Competence regulation

Genomic Context

Location: 10839..21438
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RF668_RS00065 (RF668_00065) - 12997..14160 (+) 1164 WP_043736003.1 ABC transporter permease -
  RF668_RS00070 (RF668_00070) - 14257..14391 (+) 135 WP_014572996.1 hypothetical protein -
  RF668_RS00075 (RF668_00075) spx 14543..14941 (-) 399 WP_003129597.1 transcriptional regulator Spx -
  RF668_RS00080 (RF668_00080) - 15112..15642 (-) 531 WP_011675638.1 hypothetical protein -
  RF668_RS00085 (RF668_00085) clpP 15839..16438 (+) 600 WP_011834647.1 ATP-dependent Clp protease proteolytic subunit Regulator
  RF668_RS00090 (RF668_00090) icd 16478..17716 (-) 1239 WP_043736009.1 NADP-dependent isocitrate dehydrogenase -
  RF668_RS00095 (RF668_00095) acnA 17736..20282 (-) 2547 WP_043736011.1 aconitate hydratase AcnA -

Sequence

Protein


Download         Length: 199 a.a.        Molecular weight: 22052.21 Da        Isoelectric Point: 4.7423

>NTDB_id=876847 RF668_RS00085 WP_011834647.1 15839..16438(+) (clpP) [Lactococcus cremoris strain KCKM 0438]
MGYLVPTVIEQSSRGERAYDIYSRLLKDRIIMLTGPVEDGMANSIIAQLLFLDAQDNTKDIYLYVNTPGGSVSAGLAIVD
TMNFIKSDVQTIVMGMAASMGTIIASSGTKGKRFMLPNAEYLIHQPMGGAGQGTQQTDMAIVAEQLLKTRKRLEQILADN
SNRSLEQIHKDAERDHWMDAKETLEYGFIDEIMENNSLK

Nucleotide


Download         Length: 600 bp        

>NTDB_id=876847 RF668_RS00085 WP_011834647.1 15839..16438(+) (clpP) [Lactococcus cremoris strain KCKM 0438]
ATGGGTTATTTAGTACCTACCGTTATTGAACAATCAAGCCGTGGTGAACGTGCTTATGATATTTATTCACGACTTTTAAA
AGACCGTATTATCATGCTGACAGGACCTGTTGAAGATGGTATGGCAAATTCTATCATTGCCCAACTTCTTTTCTTGGATG
CACAAGATAATACTAAAGACATTTATCTCTATGTAAACACACCTGGTGGTTCTGTATCAGCTGGGCTCGCTATCGTGGAT
ACAATGAACTTTATCAAATCGGATGTCCAAACTATCGTTATGGGAATGGCTGCTTCTATGGGAACAATCATCGCCTCAAG
CGGTACTAAGGGTAAACGATTCATGTTACCAAATGCTGAATACCTCATTCACCAACCAATGGGTGGTGCAGGTCAAGGTA
CTCAACAAACTGATATGGCAATCGTCGCCGAACAACTTTTGAAAACACGTAAACGTTTGGAACAAATCCTTGCTGATAAT
TCTAATCGCTCACTTGAACAAATTCACAAAGATGCTGAGCGTGACCATTGGATGGATGCCAAAGAAACTTTAGAATATGG
TTTCATTGATGAAATTATGGAAAATAATTCATTAAAATAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(14-195)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A166TF89

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Lactococcus lactis subsp. cremoris KW2

100

100

1
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

99.497

100

0.995
  clpP Streptococcus mutans UA159

87.245

98.492

0.859
  clpP Streptococcus thermophilus LMD-9

86.735

98.492

0.854
  clpP Streptococcus thermophilus LMG 18311

86.735

98.492

0.854
  clpP Streptococcus pyogenes MGAS315

85.714

98.492

0.844
  clpP Streptococcus pyogenes JRS4

85.714

98.492

0.844
  clpP Streptococcus pneumoniae D39

84.615

97.99

0.829
  clpP Streptococcus pneumoniae TIGR4

84.615

97.99

0.829
  clpP Streptococcus pneumoniae R6

84.615

97.99

0.829
  clpP Streptococcus pneumoniae Rx1

84.615

97.99

0.829
  clpP Bacillus subtilis subsp. subtilis str. 168

57.895

95.477

0.553
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

56.995

96.985

0.553