Detailed information    

insolico Bioinformatically predicted

Overview

Name   clpP   Type   Regulator
Locus tag   RE438_RS14125 Genome accession   NZ_CP133557
Coordinates   2741731..2742312 (-) Length   193 a.a.
NCBI ID   WP_000991621.1    Uniprot ID   A0A4R4BLF5
Organism   Bacillus wiedmannii strain EPS29     
Function   degradation of ComK; degradation of DegU (predicted from homology)   
Competence regulation

Genomic Context

Location: 2736731..2747312
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RE438_RS14095 (RE438_14065) - 2737018..2737842 (-) 825 WP_080349717.1 PP2C family serine/threonine-protein phosphatase -
  RE438_RS14100 (RE438_14070) - 2737955..2738122 (-) 168 WP_048560840.1 hypothetical protein -
  RE438_RS14105 (RE438_14075) - 2738340..2738576 (+) 237 WP_016081307.1 hypothetical protein -
  RE438_RS14110 (RE438_14080) - 2738622..2739458 (-) 837 WP_048560839.1 proline/glycine betaine ABC transporter permease -
  RE438_RS14115 (RE438_14085) - 2739451..2740656 (-) 1206 WP_048560838.1 glycine betaine/L-proline ABC transporter ATP-binding protein -
  RE438_RS14120 (RE438_14090) - 2740828..2741685 (+) 858 WP_048560837.1 glycine betaine ABC transporter substrate-binding protein -
  RE438_RS14125 (RE438_14095) clpP 2741731..2742312 (-) 582 WP_000991621.1 ATP-dependent Clp endopeptidase proteolytic subunit ClpP Regulator
  RE438_RS14130 (RE438_14100) - 2742334..2743020 (-) 687 WP_048560836.1 RNA polymerase subunit sigma-70 -
  RE438_RS14135 (RE438_14105) - 2743164..2743484 (+) 321 WP_001125375.1 2Fe-2S iron-sulfur cluster-binding protein -
  RE438_RS14140 (RE438_14110) rpiA 2743486..2744151 (+) 666 WP_048560835.1 ribose 5-phosphate isomerase A -
  RE438_RS14145 (RE438_14115) - 2744258..2744692 (+) 435 WP_048560834.1 GNAT family N-acetyltransferase -
  RE438_RS14150 (RE438_14120) - 2744872..2745474 (-) 603 WP_048560833.1 DUF6944 family repetitive protein -
  RE438_RS14155 (RE438_14125) - 2746178..2746642 (+) 465 WP_048560832.1 hypothetical protein -

Sequence

Protein


Download         Length: 193 a.a.        Molecular weight: 21275.49 Da        Isoelectric Point: 4.9215

>NTDB_id=874847 RE438_RS14125 WP_000991621.1 2741731..2742312(-) (clpP) [Bacillus wiedmannii strain EPS29]
MNAIPYVVEQTKLGERSYDIYSRLLKDRIIIIGSEINDQVASSVVAQLLFLEAEDAEKDIYLYINSPGGSTTAGFAILDT
MNLIKPDVQTLCMGFAASFGALLLLSGAKGKRFALPNSEIMIHQPLGGAQGQATEIEITAKRILKLKRDINKMIAEKTGQ
SIERVAHDTERDYFMTAEEAKEYGIVDDVVTKK

Nucleotide


Download         Length: 582 bp        

>NTDB_id=874847 RE438_RS14125 WP_000991621.1 2741731..2742312(-) (clpP) [Bacillus wiedmannii strain EPS29]
ATGAATGCAATTCCATATGTAGTAGAACAAACGAAATTAGGAGAACGTTCCTATGATATATATTCAAGGTTATTAAAAGA
CCGCATTATTATTATCGGTTCAGAAATTAATGATCAAGTAGCGAGTAGTGTCGTAGCTCAATTATTATTTTTAGAAGCGG
AAGATGCAGAGAAAGATATTTATTTATACATCAACAGCCCAGGTGGTTCAACGACAGCAGGTTTTGCCATATTAGATACG
ATGAATCTAATCAAACCAGATGTGCAAACACTTTGTATGGGATTTGCAGCATCATTTGGTGCATTGTTATTATTATCAGG
TGCAAAAGGAAAACGATTTGCACTCCCTAACAGTGAAATTATGATTCATCAGCCACTTGGTGGTGCGCAAGGCCAGGCAA
CAGAAATTGAAATAACAGCGAAAAGAATACTAAAGTTAAAGCGTGATATTAATAAAATGATTGCAGAAAAAACGGGGCAA
TCGATTGAAAGAGTAGCACATGATACAGAAAGAGATTATTTTATGACTGCTGAAGAGGCAAAGGAGTATGGGATTGTAGA
TGATGTTGTTACAAAAAAATAA

Domains

Predicted by InterproScan.

Clp protease (CLP_protease)

(14-192)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A4R4BLF5

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  clpP Bacillus subtilis subsp. subtilis str. 168

68.586

98.964

0.679
  clpP Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819

68.254

97.927

0.668
  clpP Streptococcus pneumoniae Rx1

56.771

99.482

0.565
  clpP Streptococcus pneumoniae D39

56.771

99.482

0.565
  clpP Streptococcus pneumoniae R6

56.771

99.482

0.565
  clpP Streptococcus pneumoniae TIGR4

56.771

99.482

0.565
  clpP Streptococcus thermophilus LMG 18311

55.729

99.482

0.554
  clpP Streptococcus thermophilus LMD-9

55.729

99.482

0.554
  clpP Streptococcus pyogenes JRS4

55.556

97.927

0.544
  clpP Streptococcus pyogenes MGAS315

55.556

97.927

0.544
  clpP Streptococcus mutans UA159

54.497

97.927

0.534
  clpP Lactococcus lactis subsp. cremoris KW2

53.968

97.927

0.528
  clpP Lactococcus lactis subsp. lactis strain DGCC12653

51.852

97.927

0.508