NTDB

Overview

Name	comEA/celA/cilE	Type	Machinery gene
Locus tag	RDV54_RS02205	Genome accession	NZ_CP133471
Coordinates	420957..421607 (+)	Length	216 a.a.
NCBI ID	WP_000387351.1	Uniprot ID	A0AAX2L5S7
Organism	Streptococcus mitis strain LMG 14557
Function	dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 415957..426607

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RDV54_RS02175 (RDV54_02175)	frr	416205..416762 (+)	558	WP_001262225.1	ribosome recycling factor	-
RDV54_RS02180 (RDV54_02180)	cvfB	416822..417676 (+)	855	WP_001095458.1	RNA-binding virulence regulatory protein CvfB	-
RDV54_RS02185 (RDV54_02185)	-	417685..417900 (+)	216	WP_001232083.1	YozE family protein	-
RDV54_RS02190 (RDV54_02190)	-	417985..418980 (+)	996	WP_000658173.1	PhoH family protein	-
RDV54_RS02195 (RDV54_02195)	ald	419037..420149 (-)	1113	WP_000904719.1	alanine dehydrogenase	-
RDV54_RS02200 (RDV54_02200)	-	420321..420890 (+)	570	WP_000443732.1	GNAT family N-acetyltransferase	-
RDV54_RS02205 (RDV54_02205)	comEA/celA/cilE	420957..421607 (+)	651	WP_000387351.1	helix-hairpin-helix domain-containing protein	Machinery gene
RDV54_RS02210 (RDV54_02210)	comEC/celB	421591..423831 (+)	2241	WP_000942409.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
RDV54_RS02215 (RDV54_02215)	infC	424051..424581 (+)	531	WP_000848180.1	translation initiation factor IF-3	-
RDV54_RS02220 (RDV54_02220)	rpmI	424614..424814 (+)	201	WP_001125943.1	50S ribosomal protein L35	-
RDV54_RS02225 (RDV54_02225)	rplT	424866..425225 (+)	360	WP_000124834.1	50S ribosomal protein L20	-

Sequence

Protein

Download Length: 216 a.a. Molecular weight: 23173.54 Da Isoelectric Point: 6.0746

                                >NTDB_id=874468 RDV54_RS02205 WP_000387351.1 420957..421607(+) (comEA/celA/cilE) [Streptococcus mitis strain LMG 14557]

MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVVAVSKDSVSEKEVKKEEKEEPLEQDLITVDVKG

AVKSPGIYDLPVGSRVNDAVQKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEEAASQQAGPGTASSTSKEKKVNLNKA

SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGAKTIEKLKDYVTVD

Nucleotide

Download Length: 651 bp

                                >NTDB_id=874468 RDV54_RS02205 WP_000387351.1 420957..421607(+) (comEA/celA/cilE) [Streptococcus mitis strain LMG 14557]

ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATTGTTATCTGTACTGGTCTGGGATTACTTGTCGGAGGATT

TTTCCTGCTAAAGCCAGCTCCACAAACACCTGTCAAGGAAACGAATTTGCAGGCAGAAGTTGTAGCAGTTTCCAAGGATT

CGGTATCCGAAAAGGAAGTAAAGAAGGAAGAAAAGGAAGAACCCCTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT

GCTGTTAAATCGCCAGGGATTTATGATTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCAGAAGGCTGGTGGCTTGAC

AGAACAAGCAGATAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGACGAGGCTCTGGTTTACGTCCCAACTAAGGGAG

AAGAAGCAGCTAGTCAGCAGGCAGGTCCTGGGACGGCTTCCTCAACGAGCAAGGAAAAGAAGGTCAATCTCAATAAGGCC

AGTCTGGAAGAACTCAAGCAGGTCAAAGGACTGGGTGGCAAACGAGCTCAGGATATTATCGACCATCGTGAGGCAAATGG

GAAATTCAAGTCGGTTGATGAACTCAAGAAAGTCTCTGGCATTGGTGCCAAGACCATAGAAAAGTTAAAAGATTATGTTA

CAGTGGATTAA

Domains

Predicted by InterproScan.

SLBB domain (SLBB)

(76-126)

Helix-hairpin-helix motif (HHH_3)

(151-214)

Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.

3D structure

Source	ID	Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.

Visualization of predicted probability:

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	H_a-value
comEA/celA/cilE	Streptococcus mitis NCTC 12261	100	100	1
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	96.759	100	0.968
comEA/celA/cilE	Streptococcus pneumoniae Rx1	96.296	100	0.963
comEA/celA/cilE	Streptococcus pneumoniae D39	96.296	100	0.963
comEA/celA/cilE	Streptococcus pneumoniae R6	96.296	100	0.963
comEA/celA/cilE	Streptococcus mitis SK321	92.593	100	0.926
comEA	Lactococcus lactis subsp. cremoris KW2	40.889	100	0.426
comEA	Latilactobacillus sakei subsp. sakei 23K	34.335	100	0.37

Detailed information NTG0874468