Detailed information NTG0874469

Bioinformatically predicted

Overview

• Name: comEC/celB
• Type: Machinery gene
• Locus tag: RDV54_RS02210
• Genome accession: NZ_CP133471
• Coordinates: 421591..423831 (+)
• Length: 746 a.a.
• NCBI ID: WP_000942409.1
• Uniprot ID: -
• Organism: Streptococcus mitis strain LMG 14557
• Function: ssDNA transport into the cell (predicted from homology) DNA binding and uptake

Genomic Context

Location: 416591..428831

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
RDV54_RS02180 (RDV54_02180)	cvfB	416822..417676 (+)	855	WP_001095458.1	RNA-binding virulence regulatory protein CvfB	-
RDV54_RS02185 (RDV54_02185)	-	417685..417900 (+)	216	WP_001232083.1	YozE family protein	-
RDV54_RS02190 (RDV54_02190)	-	417985..418980 (+)	996	WP_000658173.1	PhoH family protein	-
RDV54_RS02195 (RDV54_02195)	ald	419037..420149 (-)	1113	WP_000904719.1	alanine dehydrogenase	-
RDV54_RS02200 (RDV54_02200)	-	420321..420890 (+)	570	WP_000443732.1	GNAT family N-acetyltransferase	-
RDV54_RS02205 (RDV54_02205)	comEA/celA/cilE	420957..421607 (+)	651	WP_000387351.1	helix-hairpin-helix domain-containing protein	Machinery gene
RDV54_RS02210 (RDV54_02210)	comEC/celB	421591..423831 (+)	2241	WP_000942409.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
RDV54_RS02215 (RDV54_02215)	infC	424051..424581 (+)	531	WP_000848180.1	translation initiation factor IF-3	-
RDV54_RS02220 (RDV54_02220)	rpmI	424614..424814 (+)	201	WP_001125943.1	50S ribosomal protein L35	-
RDV54_RS02225 (RDV54_02225)	rplT	424866..425225 (+)	360	WP_000124834.1	50S ribosomal protein L20	-
RDV54_RS02230 (RDV54_02230)	-	425401..427065 (+)	1665	WP_000635031.1	molecular chaperone HscC	-

Sequence

Protein

• Length: 746 a.a.
• Molecular weight: 84460.75 Da
• Isoelectric Point: 9.5655

>NTDB_id=874469 RDV54_RS02210 WP_000942409.1 421591..423831(+) (comEC/celB) [Streptococcus mitis strain LMG 14557]
MLQWIKNFSIPLIYLSFLLLWLYYAIFSSSYLALLGFVFLLVCLFIQFPWKSAGKVLIICGIFGFWFLFQNWQQSQASQN
LADSVERVRILPDTVKVNGDSLSFRGKSDGRIFQVYYKLQSEEEKEAFQALTDLHEIGLEGKLSEPDGQRNFGGFDYQAY
LKTQGIYQTLTIKRIQSLQKVSSWDIGENLSSLRRKTVVWIKTHFPDPMRNYMTGLLLGHLDTDFEEMNGLYSSLGIIHL
FALSGMQVGFFMDGFKKLLLRLGLTQEKLKWLTYPFSLIYAGLTGFSASVIRSLLQKLLAQHGVKGLDNFALTVLVLFIV
MPNFFLTAGGVLSCAYAFILTMTSKEGEGLKAVARESLVISLGILPILSFYFAEFQPWSILLTFVFSFLFDLVFLPLLSI
LFALSFLHPVIQLNFIFEWLEGMIRFVSQVASRPLVFGQPNAWILILLLISLALVYDLRKNIKRLAVLSLLITGLFFLTK
HPLENEITMLDVGQGESIFLRDVTGKIILIDVGGKAESSKKIEKWQEKTTTSNAQRTLIPYLKSRGVSKIDQLILTNTDK
EYVGDLLEVTKAFHVGEILVSKGSLKQKQFVAELQATQTKVRSITAGENLSIFGSQLEVLSPRKIGDGGYEDSLVLYGKL
LDKYFLFTGNLEEKGEKELLKHYPDLKVDVLKAGQHGSKKSSSSDFLEKLKPEFTLISVGKNNRAKLPHQETLTRLETIN
SKVYRTDQHGAIRFKGWNSWKVETVG

Nucleotide

• Length: 2241 bp

>NTDB_id=874469 RDV54_RS02210 WP_000942409.1 421591..423831(+) (comEC/celB) [Streptococcus mitis strain LMG 14557]
ATGTTACAGTGGATTAAGAATTTCTCTATTCCCCTAATTTACCTTAGTTTTCTGTTGCTTTGGCTTTACTACGCCATTTT
CTCATCATCTTATCTCGCACTACTAGGTTTTGTTTTTCTGCTAGTCTGTCTCTTTATCCAATTTCCGTGGAAATCTGCTG
GTAAAGTTCTAATAATTTGTGGAATCTTTGGTTTCTGGTTTCTGTTTCAAAATTGGCAACAGAGTCAAGCGAGTCAAAAT
TTGGCGGATTCTGTTGAAAGGGTACGGATTTTACCAGACACTGTTAAGGTCAATGGTGATAGTCTATCCTTTCGTGGTAA
GTCTGATGGACGCATTTTTCAAGTCTATTATAAACTCCAGTCCGAGGAGGAGAAAGAAGCCTTTCAAGCTTTAACCGACC
TTCATGAGATAGGACTAGAAGGAAAACTTTCAGAACCAGACGGGCAGAGAAATTTTGGTGGTTTTGACTACCAAGCCTAT
CTGAAAACTCAAGGGATTTACCAAACATTAACTATCAAAAGAATCCAGTCACTTCAAAAGGTTAGCAGTTGGGATATAGG
AGAAAATCTGTCCAGTTTACGTCGAAAGACTGTGGTTTGGATTAAGACGCATTTTCCAGACCCTATGCGCAATTACATGA
CAGGGCTCTTGTTAGGACATCTGGACACCGACTTTGAGGAGATGAACGGGCTTTATTCTAGTTTAGGAATTATCCACCTC
TTTGCCTTGTCGGGTATGCAGGTAGGTTTTTTCATGGACGGATTTAAGAAACTCCTCTTGCGATTGGGCTTGACTCAAGA
AAAGTTGAAATGGCTGACTTATCCCTTTTCCCTTATCTATGCAGGGCTGACAGGATTTTCAGCATCAGTTATTCGCAGTC
TTTTGCAAAAGTTACTGGCACAACATGGTGTTAAGGGCTTGGATAATTTTGCCTTGACGGTCCTTGTCCTCTTTATCGTC
ATGCCCAACTTTTTCTTGACAGCAGGAGGAGTCTTGTCCTGCGCTTATGCTTTTATCTTGACCATGACCAGCAAAGAAGG
AGAAGGCCTCAAGGCTGTTGCTAGAGAAAGTCTAGTCATTTCCTTGGGAATATTACCCATCCTATCCTTCTATTTTGCAG
AATTTCAGCCTTGGTCTATCCTTTTGACCTTTGTCTTTTCCTTTCTTTTTGACTTGGTCTTCTTACCGCTCTTGTCTATC
TTATTTGCCCTTTCCTTTCTTCATCCAGTCATTCAGCTGAATTTTATTTTTGAATGGTTGGAGGGAATGATTCGCTTTGT
ATCACAGGTGGCAAGTAGACCTCTGGTCTTTGGACAACCCAATGCATGGATTTTAATCTTATTGTTAATTTCCTTGGCTT
TGGTCTATGATTTGAGGAAAAACATTAAAAGGCTAGCAGTGTTGAGCTTATTGATTACAGGTCTCTTTTTCTTGACCAAG
CATCCACTGGAAAATGAAATCACCATGCTGGATGTTGGGCAAGGGGAAAGTATTTTCCTACGGGATGTAACTGGTAAAAT
CATTCTCATAGATGTGGGTGGCAAGGCAGAGTCTAGTAAGAAAATAGAAAAATGGCAAGAAAAGACGACGACCAGTAATG
CCCAGCGAACCTTGATACCCTATCTCAAAAGTCGCGGAGTATCCAAGATTGACCAGCTAATTTTGACCAATACGGACAAG
GAATATGTTGGAGATTTGTTGGAGGTGACCAAGGCTTTTCATGTAGGCGAAATTTTAGTGTCAAAAGGCAGTTTGAAACA
GAAGCAATTTGTGGCAGAACTACAAGCGACCCAAACAAAAGTTAGAAGTATAACAGCAGGAGAGAACTTGTCAATTTTTG
GAAGTCAGTTAGAAGTCCTATCTCCAAGGAAAATTGGAGATGGAGGTTATGAAGATTCCCTGGTTCTGTATGGAAAACTT
TTGGATAAGTACTTTCTCTTCACAGGAAATTTGGAGGAAAAAGGAGAGAAGGAATTGCTGAAGCACTATCCAGACTTGAA
AGTGGATGTTTTAAAAGCTGGCCAACATGGCTCTAAAAAATCATCAAGTTCAGACTTTCTAGAAAAACTCAAACCAGAGT
TTACTCTTATCTCAGTTGGAAAGAACAATCGAGCGAAACTCCCCCATCAGGAAACTTTGACACGACTGGAAACTATCAAT
AGTAAAGTTTACCGAACTGACCAGCATGGAGCTATACGCTTTAAAGGGTGGAATAGTTGGAAAGTCGAAACGGTTGGTTA
A

Domains

Predicted by InterproScan.

• Metallo-beta-lactamase superfamily (Lactamase_B) (492-693)

• Domain of unknown function (DUF4131) (DUF4131) (29-176)

• Competence protein (Competence) (216-458)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEC/celB	Streptococcus mitis NCTC 12261	100	100	1
comEC/celB	Streptococcus mitis SK321	91.946	99.866	0.918
comEC/celB	Streptococcus pneumoniae TIGR4	91.812	99.866	0.917
comEC/celB	Streptococcus pneumoniae D39	91.544	99.866	0.914
comEC/celB	Streptococcus pneumoniae Rx1	91.544	99.866	0.914
comEC/celB	Streptococcus pneumoniae R6	91.544	99.866	0.914
comEC	Lactococcus lactis subsp. cremoris KW2	44.459	99.196	0.441