Detailed information    

insolico Bioinformatically predicted

Overview


Name   prx   Type   Regulator
Locus tag   RA106_RS03935 Genome accession   NZ_CP132900
Coordinates   740446..740607 (-) Length   53 a.a.
NCBI ID   WP_014727422.1    Uniprot ID   -
Organism   Streptococcus thermophilus strain CICC 20372     
Function   Inhibit ComR activation (predicted from homology)   
Competence regulation

Related MGE


Note: This gene co-localizes with putative mobile genetic elements (MGEs) in the genome predicted by VRprofile2, as detailed below.

Gene-MGE association summary

MGE type MGE coordinates Gene coordinates Relative position Distance (bp)
Prophage 740446..748303 740446..740607 within 0


Gene organization within MGE regions


Location: 740446..748303
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  RA106_RS03935 (RA106_03945) prx 740446..740607 (-) 162 WP_014727422.1 hypothetical protein Regulator
  RA106_RS03940 (RA106_03950) - 741091..741366 (-) 276 WP_014727423.1 hypothetical protein -
  RA106_RS03945 (RA106_03955) - 741383..741568 (-) 186 WP_024704073.1 hypothetical protein -
  RA106_RS03950 (RA106_03960) - 741866..743371 (-) 1506 WP_024704074.1 phage/plasmid primase, P4 family -
  RA106_RS03955 (RA106_03965) - 743361..744221 (-) 861 WP_024704075.1 primase alpha helix C-terminal domain-containing protein -
  RA106_RS03960 (RA106_03970) - 744236..744508 (-) 273 WP_011227098.1 MerR family transcriptional regulator -
  RA106_RS03965 (RA106_03975) - 744751..744987 (-) 237 WP_024704076.1 hypothetical protein -
  RA106_RS03970 (RA106_03980) - 745001..745195 (-) 195 WP_024704077.1 hypothetical protein -
  RA106_RS03975 (RA106_03985) - 745199..745492 (-) 294 WP_024704078.1 hypothetical protein -
  RA106_RS03980 (RA106_03990) - 745731..745928 (-) 198 WP_014608200.1 helix-turn-helix transcriptional regulator -
  RA106_RS03985 (RA106_03995) - 746109..746603 (+) 495 WP_370869443.1 helix-turn-helix transcriptional regulator -
  RA106_RS03990 (RA106_04000) - 746686..747852 (+) 1167 WP_011227104.1 site-specific integrase -
  RA106_RS03995 (RA106_04005) - 747968..748303 (+) 336 WP_002948199.1 hypothetical protein -

Sequence


Protein


Download         Length: 53 a.a.        Molecular weight: 6084.95 Da        Isoelectric Point: 4.2412

>NTDB_id=870543 RA106_RS03935 WP_014727422.1 740446..740607(-) (prx) [Streptococcus thermophilus strain CICC 20372]
MLTYDEFKEAMDKGFIKGDTVQIVRLDGEQVEPREILSLEKVSDIIKELGKDN

Nucleotide


Download         Length: 162 bp        

>NTDB_id=870543 RA106_RS03935 WP_014727422.1 740446..740607(-) (prx) [Streptococcus thermophilus strain CICC 20372]
ATGCTGACTTATGATGAATTTAAAGAGGCAATGGACAAGGGTTTTATTAAAGGTGATACTGTCCAGATTGTCCGATTAGA
CGGTGAACAAGTTGAGCCACGCGAAATATTGAGCTTAGAAAAGGTATCGGATATAATAAAGGAACTAGGCAAGGACAACT
AA

Domains



No domain identified.



Secondary structure


Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure


Source ID Structure

Transmembrane helices


Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.



Visualization of predicted probability:


Similar proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  prx Streptococcus pyogenes MGAS8232

48.333

100

0.547

  prx Streptococcus pyogenes MGAS315

46.667

100

0.528

  prx Streptococcus pyogenes MGAS315

46.667

100

0.528

  prx Streptococcus pyogenes MGAS315

45

100

0.509

  prx Streptococcus pyogenes MGAS315

56.818

83.019

0.472

  prx Streptococcus pyogenes MGAS315

57.143

79.245

0.453

  prx Streptococcus pyogenes MGAS315

60.526

71.698

0.434