Detailed information NTG0867069

Bioinformatically predicted

Overview

• Name: clpP
• Type: Regulator
• Locus tag: Q8W18_RS16245
• Genome accession: NZ_CP132058
• Coordinates: 3131176..3131772 (+)
• Length: 198 a.a.
• NCBI ID: WP_024719872.1
• Uniprot ID: A0A2G8ISB7
• Organism: Bacillus pumilus strain F12-21
• Function: degradation of ComK; degradation of DegU (predicted from homology) Competence regulation

Genomic Context

Location: 3126176..3136772

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
Q8W18_RS16220 (Q8W18_16220)	abc-f	3126187..3127746 (-)	1560	WP_306012276.1	ribosomal protection-like ABC-F family protein	-
Q8W18_RS16225 (Q8W18_16225)	-	3128232..3129401 (-)	1170	WP_180310052.1	macrolide family glycosyltransferase	-
Q8W18_RS16230 (Q8W18_16230)	-	3129667..3130131 (-)	465	WP_306011232.1	DinB family protein	-
Q8W18_RS16240 (Q8W18_16240)	-	3130642..3130947 (-)	306	WP_050944247.1	TM2 domain-containing protein	-
Q8W18_RS16245 (Q8W18_16245)	clpP	3131176..3131772 (+)	597	WP_024719872.1	ATP-dependent Clp endopeptidase proteolytic subunit ClpP	Regulator
Q8W18_RS16250 (Q8W18_16250)	-	3131832..3132410 (-)	579	WP_058013625.1	TIGR00730 family Rossman fold protein	-
Q8W18_RS16255 (Q8W18_16255)	-	3132547..3132876 (+)	330	WP_058013624.1	MazG nucleotide pyrophosphohydrolase domain-containing protein	-
Q8W18_RS16260 (Q8W18_16260)	-	3132905..3134527 (-)	1623	WP_306011234.1	SulP family inorganic anion transporter	-
Q8W18_RS16265 (Q8W18_16265)	-	3134565..3135146 (-)	582	WP_119125413.1	carbonic anhydrase	-
Q8W18_RS16270 (Q8W18_16270)	-	3135698..3136675 (+)	978	WP_306011235.1	D-glycerate dehydrogenase	-

Sequence

Protein

• Length: 198 a.a.
• Molecular weight: 21832.00 Da
• Isoelectric Point: 4.6905

>NTDB_id=867069 Q8W18_RS16245 WP_024719872.1 3131176..3131772(+) (clpP) [Bacillus pumilus strain F12-21]
MNLIPTVIEQTNRGERAYDIYSRLLKDRIIMLGSAIDDNVANSIVSQLLFLEAEDPEKDISIYINSPGGSITAGMAIYDT
MQFIKPKVSTICIGMAASMGAFLLAAGEKGKRYALPNSEVMIHQPLGGAQGQATEIEIAAKRILSLRDKLNQVLAERTGQ
PIEVIERDTDRDNFKTAEEALQYGLIDKVLTRNSEEQK

Nucleotide

• Length: 597 bp

>NTDB_id=867069 Q8W18_RS16245 WP_024719872.1 3131176..3131772(+) (clpP) [Bacillus pumilus strain F12-21]
ATGAATTTAATACCTACAGTCATTGAGCAAACAAATCGTGGGGAAAGAGCTTACGACATTTATTCTCGTCTTTTAAAAGA
CCGTATTATCATGCTTGGTTCTGCGATCGATGACAATGTTGCCAACTCCATCGTGTCACAGCTGCTTTTCTTAGAAGCTG
AAGATCCAGAAAAAGATATTTCTATCTACATTAACAGCCCTGGCGGTTCAATCACAGCTGGTATGGCCATTTACGATACG
ATGCAATTTATTAAACCAAAGGTATCAACCATTTGTATTGGTATGGCTGCATCTATGGGTGCGTTCCTGCTTGCTGCTGG
TGAAAAAGGTAAGCGTTATGCCCTTCCAAACAGTGAAGTCATGATTCACCAACCACTAGGTGGTGCCCAAGGTCAAGCAA
CAGAAATTGAAATTGCGGCAAAACGAATCCTTTCTTTACGTGATAAACTGAACCAAGTACTTGCTGAACGTACTGGTCAG
CCAATTGAAGTCATTGAGCGCGATACAGATCGTGACAACTTCAAAACAGCGGAAGAAGCACTTCAATACGGACTCATTGA
CAAAGTCTTGACCCGTAACTCAGAAGAACAAAAATAA

Domains

Predicted by InterproScan.

• Clp protease (CLP_protease) (13-192)

3D structure

• AlphaFold DB: A0A2G8ISB7

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
clpP	Bacillus subtilis subsp. subtilis str. 168	92.929	100	0.929
clpP	Campylobacter jejuni subsp. jejuni NCTC 11168 = ATCC 700819	67.539	96.465	0.652
clpP	Streptococcus thermophilus LMG 18311	58.549	97.475	0.571
clpP	Streptococcus thermophilus LMD-9	58.549	97.475	0.571
clpP	Lactococcus lactis subsp. cremoris KW2	56.701	97.98	0.556
clpP	Streptococcus pneumoniae Rx1	56.186	97.98	0.551
clpP	Streptococcus pneumoniae D39	56.186	97.98	0.551
clpP	Streptococcus pneumoniae R6	56.186	97.98	0.551
clpP	Streptococcus pneumoniae TIGR4	56.186	97.98	0.551
clpP	Streptococcus pyogenes JRS4	55.44	97.475	0.54
clpP	Streptococcus pyogenes MGAS315	55.44	97.475	0.54
clpP	Streptococcus mutans UA159	54.639	97.98	0.535
clpP	Lactococcus lactis subsp. lactis strain DGCC12653	54.639	97.98	0.535