Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE   Type   Machinery gene
Locus tag   Q7616_RS03140 Genome accession   NZ_CP131717
Coordinates   623745..625085 (+) Length   446 a.a.
NCBI ID   WP_342120402.1    Uniprot ID   -
Organism   Haemophilus influenzae strain 2016N21-284     
Function   type IV pilus biogenesis and function (predicted from homology)   
DNA binding and uptake

Genomic Context

Location: 618745..630085
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  Q7616_RS03115 (Q7616_03120) - 618810..621404 (-) 2595 WP_118806713.1 penicillin-binding protein 1A -
  Q7616_RS03120 (Q7616_03125) comA 621503..622300 (+) 798 WP_342120400.1 competence protein ComA Machinery gene
  Q7616_RS03125 (Q7616_03130) comB 622301..622807 (+) 507 WP_105873321.1 competence protein B Machinery gene
  Q7616_RS03130 (Q7616_03135) comC 622804..623325 (+) 522 WP_342120401.1 competence protein ComC Machinery gene
  Q7616_RS03135 (Q7616_03140) comD 623322..623735 (+) 414 WP_021034381.1 pilus assembly protein PilP Machinery gene
  Q7616_RS03140 (Q7616_03145) comE 623745..625085 (+) 1341 WP_342120402.1 type IV pilus secretin PilQ family protein Machinery gene
  Q7616_RS03145 (Q7616_03150) - 625098..625784 (+) 687 WP_005669238.1 ComF family protein -
  Q7616_RS03150 (Q7616_03155) nfuA 625860..626456 (+) 597 WP_005649300.1 Fe-S biogenesis protein NfuA -
  Q7616_RS03155 (Q7616_03160) nudC 626523..627317 (+) 795 WP_014550416.1 NAD(+) diphosphatase -
  Q7616_RS03160 (Q7616_03165) - 627353..627943 (+) 591 WP_005656455.1 YjaG family protein -
  Q7616_RS03165 (Q7616_03170) - 628083..628355 (+) 273 WP_014550417.1 HU family DNA-binding protein -

Sequence

Protein


Download         Length: 446 a.a.        Molecular weight: 49362.58 Da        Isoelectric Point: 7.8653

>NTDB_id=864611 Q7616_RS03140 WP_342120402.1 623745..625085(+) (comE) [Haemophilus influenzae strain 2016N21-284]
MKKYFLKCGYFLMCFCLPLIVFANPKTDNERFFIRLSQAPLSQTLEQLAFQQDVNLVIGDTLENKISLKLNNIDMPRLLQ
IIAKSKHLRLNKDDDIYYLNGGQSGSKGQVAGNLTTNEPHLVSHTVKLHFAKASELMKSLTTGSGSLLSPAGSITFDDRS
NLLVIQDESRSVQNIKKLISEMDKPIEQIAIEARIVTITDESLKELGVRWGIFNPTENARRVAGSLTGNSFENIADNLNV
NFATTTTPAGSIALQVAKINGRLLDLELSALERENNVEIIASPRLLTTNKKSASIKQGTEIPYIVSNTRNDTQSVEFREA
VLGLEVTPHISKDNNILLDLLVSQNSPGSRVAYGQNEVVSIDKQEINTQVFAKDGETIVLGGVFHDTITKSEDKVPLLGD
IPVIKRLFSKESERHQKRELVIFVTPHILKAGETLEALKQKSAGKK

Nucleotide


Download         Length: 1341 bp        

>NTDB_id=864611 Q7616_RS03140 WP_342120402.1 623745..625085(+) (comE) [Haemophilus influenzae strain 2016N21-284]
ATGAAGAAATATTTTTTAAAGTGCGGTTATTTTCTAATGTGTTTTTGTTTGCCTTTAATTGTTTTTGCTAATCCTAAAAC
AGATAACGAACGTTTTTTTATTCGTTTATCGCAAGCACCTTTATCCCAAACATTGGAACAGTTGGCTTTTCAACAAGATG
TGAATTTAGTGATTGGAGATACATTGGAAAACAAGATCTCTTTGAAATTAAATAATATTGATATGCCACGTTTGCTACAA
ATAATCGCTAAAAGTAAGCATCTTAGGCTGAATAAAGACGACGATATTTATTATCTGAATGGAGGGCAATCAGGCAGCAA
AGGGCAAGTTGCAGGAAATCTTACTACAAATGAACCGCACTTAGTGAGTCACACGGTAAAACTCCATTTTGCTAAAGCCT
CTGAATTAATGAAATCCTTAACGACAGGAAGTGGCTCTTTGCTTTCACCAGCTGGGAGTATTACCTTTGATGATCGCAGT
AATTTGCTCGTGATTCAAGATGAGTCTCGTTCTGTGCAGAATATCAAAAAACTAATTTCTGAAATGGATAAACCTATTGA
GCAGATCGCTATTGAAGCACGAATTGTGACAATTACGGATGAGAGTTTGAAAGAACTTGGCGTTCGGTGGGGGATTTTTA
ATCCAACTGAAAATGCAAGACGAGTTGCGGGCAGCCTTACAGGCAATAGCTTTGAAAATATTGCGGATAATCTTAATGTA
AATTTTGCGACAACGACGACACCTGCTGGCTCTATAGCATTACAAGTCGCGAAAATTAATGGGCGATTGCTTGATTTAGA
ATTGAGTGCGTTGGAGCGTGAAAATAATGTAGAAATTATTGCAAGTCCTCGCTTACTCACTACCAATAAGAAAAGTGCGA
GCATTAAACAGGGGACAGAAATTCCTTACATCGTGAGTAATACTCGTAACGATACGCAATCTGTGGAATTTCGTGAGGCA
GTACTTGGTTTGGAAGTGACGCCACATATTTCTAAAGATAACAATATCTTACTTGATTTATTGGTAAGTCAAAATTCCCC
TGGTTCTCGTGTCGCTTATGGACAAAATGAGGTGGTTTCTATTGATAAACAAGAAATTAATACTCAGGTTTTTGCCAAAG
ATGGGGAAACCATTGTGCTTGGCGGCGTATTTCACGACACAATCACGAAAAGCGAAGATAAAGTGCCATTGCTTGGCGAT
ATACCTGTTATTAAACGATTATTTAGCAAAGAAAGTGAACGACATCAAAAACGTGAGCTCGTGATTTTCGTCACGCCGCA
TATTTTAAAAGCAGGAGAAACGTTAGAGGCGTTGAAACAAAAAAGTGCGGGGAAAAAATAA

Domains

Predicted by InterproScan.

Bacterial type II/III secretion system short domain (Secretin_N)

(124-188)

Bacterial type II and III secretion system protein (Secretin)

(270-430)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE Haemophilus influenzae Rd KW20

97.758

100

0.978
  comE Haemophilus influenzae 86-028NP

95.964

100

0.96
  comE Glaesserella parasuis strain SC1401

52.347

95.516

0.5
  pilQ Vibrio campbellii strain DS40M4

42.243

93.946

0.397
  pilQ Vibrio cholerae O1 biovar El Tor strain E7946

42.067

93.274

0.392
  pilQ Vibrio cholerae strain A1552

42.067

93.274

0.392