Detailed information NTG0085749

Bioinformatically predicted

Overview

• Name: micA
• Type: Regulator
• Locus tag: STYK_RS06170
• Genome accession: NZ_AP024523
• Coordinates: 1193780..1194487 (-)
• Length: 235 a.a.
• NCBI ID: WP_000722071.1
• Uniprot ID: -
• Organism: Streptococcus toyakuensis strain TP1632
• Function: repress competence development (predicted from homology) Competence regulation

Genomic Context

Location: 1188780..1199487

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
STYK_RS06140 (STYK_11620)	-	1189834..1190181 (+)	348	WP_023944304.1	thioredoxin	-
STYK_RS06145 (STYK_11630)	-	1190219..1190992 (-)	774	WP_261804713.1	potassium channel family protein	-
STYK_RS06150 (STYK_11640)	-	1191038..1191292 (-)	255	WP_191962389.1	type II toxin-antitoxin system RelE family toxin	-
STYK_RS06155 (STYK_11650)	relB	1191294..1191536 (-)	243	WP_000208079.1	type II toxin-antitoxin system RelB family antitoxin	-
STYK_RS06160 (STYK_11660)	vicX	1191627..1192436 (-)	810	WP_004254224.1	MBL fold metallo-hydrolase	Regulator
STYK_RS06165 (STYK_11670)	micB	1192429..1193787 (-)	1359	WP_261804714.1	cell wall metabolism sensor histidine kinase VicK	Regulator
STYK_RS06170 (STYK_11680)	micA	1193780..1194487 (-)	708	WP_000722071.1	response regulator YycF	Regulator
STYK_RS06175 (STYK_11690)	mutY	1194542..1195717 (-)	1176	WP_261804715.1	A/G-specific adenine glycosylase	-
STYK_RS06180 (STYK_11700)	pta	1195906..1196880 (-)	975	WP_000451571.1	phosphate acetyltransferase	-
STYK_RS06185 (STYK_11710)	-	1196924..1197820 (-)	897	WP_261086611.1	RluA family pseudouridine synthase	-
STYK_RS06190 (STYK_11720)	-	1197817..1198635 (-)	819	WP_033681742.1	NAD kinase	-
STYK_RS06195 (STYK_11730)	-	1198619..1199290 (-)	672	WP_033687049.1	GTP pyrophosphokinase	-

Sequence

Protein

• Length: 235 a.a.
• Molecular weight: 27065.78 Da
• Isoelectric Point: 4.5600

>NTDB_id=85749 STYK_RS06170 WP_000722071.1 1193780..1194487(-) (micA) [Streptococcus toyakuensis strain TP1632]
MKKILIVDDEKPISDIIKFNMTKEGYEVVTAFNGREALEQFEAEQPDIIILDLMLPEIDGLEVAKTIRKTSSVPIIMLSA
KDSEFDKVIGLELGADDYVTKPFSNRELQARVKALLRRTDLASVDNQESDENKTQPLQIGDLEIVPDAYVAKKYGEELDL
THREFELLYHLASHIGQVITREHLLETVWGYDYFGDVRTVDVTIRRLREKIEDTPSRPEYILTRRGVGYYMRNND

Nucleotide

• Length: 708 bp

>NTDB_id=85749 STYK_RS06170 WP_000722071.1 1193780..1194487(-) (micA) [Streptococcus toyakuensis strain TP1632]
ATGAAAAAAATATTAATTGTAGATGATGAAAAACCAATCTCGGATATTATCAAGTTTAATATGACCAAGGAAGGTTACGA
GGTTGTAACTGCTTTTAACGGTCGTGAAGCGCTAGAACAATTTGAAGCAGAGCAACCAGATATTATTATTTTGGACTTGA
TGCTTCCAGAAATTGATGGCTTAGAAGTTGCGAAGACTATTCGGAAGACTAGTAGTGTGCCTATTATCATGCTGTCAGCT
AAGGATAGCGAATTTGATAAGGTTATCGGTTTAGAGCTTGGGGCGGATGACTATGTGACAAAACCCTTCTCAAATCGTGA
GTTGCAGGCGCGTGTTAAAGCTCTCCTTCGTCGCACGGACTTGGCTTCTGTAGATAATCAAGAATCAGATGAAAATAAAA
CTCAACCCTTGCAAATTGGGGACTTAGAGATTGTTCCAGATGCCTATGTTGCTAAGAAATACGGTGAAGAACTAGACTTA
ACTCACCGTGAATTTGAGCTTTTGTATCACTTGGCTTCTCATATCGGTCAAGTAATTACGCGTGAACACTTGCTTGAAAC
GGTCTGGGGTTATGATTATTTCGGAGATGTTCGAACAGTTGACGTAACTATCAGACGTTTGCGCGAGAAGATTGAAGATA
CACCTAGTCGTCCAGAGTATATCCTAACACGTCGTGGTGTTGGTTATTATATGAGAAATAATGATTGA

Domains

Predicted by InterproScan.

• Transcriptional regulatory protein, C terminal (Trans_reg_C) (155-230)

• Response regulator receiver domain (Response_reg) (4-112)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
micA	Streptococcus pneumoniae Cp1015	94.017	99.574	0.936
vicR	Streptococcus mutans UA159	77.447	100	0.774
covR	Lactococcus lactis subsp. lactis strain DGCC12653	45.022	98.298	0.443
covR	Streptococcus salivarius strain HSISS4	44.589	98.298	0.438
scnR	Streptococcus mutans UA159	38.034	99.574	0.379