Detailed information    

insolico Bioinformatically predicted

Overview

Name   micB   Type   Regulator
Locus tag   STYK_RS06165 Genome accession   NZ_AP024523
Coordinates   1192429..1193787 (-) Length   452 a.a.
NCBI ID   WP_261804714.1    Uniprot ID   -
Organism   Streptococcus toyakuensis strain TP1632     
Function   repress competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 1187429..1198787
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  STYK_RS06135 (STYK_11610) - 1188004..1189722 (+) 1719 WP_261804712.1 phospho-sugar mutase -
  STYK_RS06140 (STYK_11620) - 1189834..1190181 (+) 348 WP_023944304.1 thioredoxin -
  STYK_RS06145 (STYK_11630) - 1190219..1190992 (-) 774 WP_261804713.1 potassium channel family protein -
  STYK_RS06150 (STYK_11640) - 1191038..1191292 (-) 255 WP_191962389.1 type II toxin-antitoxin system RelE family toxin -
  STYK_RS06155 (STYK_11650) relB 1191294..1191536 (-) 243 WP_000208079.1 type II toxin-antitoxin system RelB family antitoxin -
  STYK_RS06160 (STYK_11660) vicX 1191627..1192436 (-) 810 WP_004254224.1 MBL fold metallo-hydrolase Regulator
  STYK_RS06165 (STYK_11670) micB 1192429..1193787 (-) 1359 WP_261804714.1 cell wall metabolism sensor histidine kinase VicK Regulator
  STYK_RS06170 (STYK_11680) micA 1193780..1194487 (-) 708 WP_000722071.1 response regulator YycF Regulator
  STYK_RS06175 (STYK_11690) mutY 1194542..1195717 (-) 1176 WP_261804715.1 A/G-specific adenine glycosylase -
  STYK_RS06180 (STYK_11700) pta 1195906..1196880 (-) 975 WP_000451571.1 phosphate acetyltransferase -
  STYK_RS06185 (STYK_11710) - 1196924..1197820 (-) 897 WP_261086611.1 RluA family pseudouridine synthase -
  STYK_RS06190 (STYK_11720) - 1197817..1198635 (-) 819 WP_033681742.1 NAD kinase -

Sequence

Protein


Download         Length: 452 a.a.        Molecular weight: 51977.50 Da        Isoelectric Point: 4.7359

>NTDB_id=85748 STYK_RS06165 WP_261804714.1 1192429..1193787(-) (micB) [Streptococcus toyakuensis strain TP1632]
MIELIRKNILTSDFIFILILLGFILIVTLLLLENRRDNIRLKQINQKVKDLIAGDYSQVLDMQGSSEITNITNNLNDLSE
VIRLTQENLEQESKRLHSILSYMTDGVLATNRRGKITMINDMAKKQLGVQKEEVLNKSILELLKIEDEYELRDLITQIPE
LMIDSQDDNGEYLSLRVRFALVRRESGFISGLVAVLHDTTEQEKEERERRLFVSNVSHELRTPLTSVKSYLEALDEGALS
EPVAPDFIKVSLDETNRMMRMVTDLLHLSRIDNATSHLDVELINFTAFITFILNRFDKMRGPDEEKKYELVRDYPITSVW
IEIDTDKMTQVIDNILNNAIKYSPDGGKIKVTMKTTDDQMILSISDQGLGIPKQDLPRIFDRFYRVDRARSRAQGGTGLG
LSIAKEIIKQHNGFIWAKSEYGKGSTFTIVLPYDKDAVKEEVWEDEIEDQNE

Nucleotide


Download         Length: 1359 bp        

>NTDB_id=85748 STYK_RS06165 WP_261804714.1 1192429..1193787(-) (micB) [Streptococcus toyakuensis strain TP1632]
ATGATTGAATTGATTAGAAAAAATATTCTTACTAGTGATTTTATCTTCATTTTAATTTTATTGGGTTTTATCTTGATTGT
TACCTTGCTTTTGCTAGAAAATCGGCGAGATAATATTCGGTTGAAGCAAATTAATCAAAAAGTCAAAGATTTGATTGCAG
GAGATTATTCTCAGGTATTGGATATGCAGGGAAGCTCTGAAATCACTAATATTACCAATAATCTCAATGATTTATCAGAA
GTAATCCGTTTGACTCAAGAAAATCTGGAACAAGAGAGTAAACGATTACATAGTATCCTGTCTTACATGACGGATGGAGT
CCTTGCGACCAATCGTCGTGGCAAGATTACTATGATTAATGACATGGCTAAGAAACAGCTAGGTGTTCAGAAAGAAGAGG
TTCTCAATAAAAGTATTCTAGAATTGCTTAAGATTGAAGATGAGTATGAACTTCGTGATTTGATTACGCAGATTCCTGAA
CTCATGATTGATTCTCAGGATGACAATGGTGAATATCTGAGCCTTCGTGTACGCTTTGCCTTGGTCCGTCGAGAATCTGG
CTTTATCTCAGGTCTGGTTGCCGTTCTGCATGATACAACGGAGCAAGAGAAGGAAGAGCGCGAACGGAGACTCTTTGTTT
CTAACGTTAGTCATGAGTTACGGACTCCACTGACTAGTGTAAAATCCTATCTTGAAGCTTTGGATGAGGGAGCCTTGTCA
GAACCTGTTGCACCAGACTTTATTAAGGTATCTCTAGACGAAACCAATCGTATGATGCGCATGGTAACTGACCTCCTCCA
TCTCTCTCGAATTGACAATGCGACCAGTCATCTGGATGTGGAACTGATTAACTTCACTGCCTTTATTACCTTTATTCTTA
ACCGTTTTGATAAGATGAGGGGACCAGACGAAGAGAAGAAATATGAATTGGTTAGAGATTATCCGATTACCTCTGTCTGG
ATTGAAATTGATACAGACAAGATGACGCAGGTGATTGATAATATTCTCAACAATGCCATCAAGTATTCACCAGATGGTGG
TAAAATTAAAGTGACAATGAAGACAACTGATGATCAGATGATTTTATCTATCTCAGACCAAGGCTTGGGTATTCCTAAGC
AGGATTTACCACGTATCTTTGACCGTTTTTATCGTGTGGATCGTGCTAGAAGTCGTGCCCAAGGTGGAACAGGTCTGGGA
CTGTCTATTGCTAAGGAAATTATCAAACAGCATAATGGCTTTATTTGGGCCAAGAGTGAATACGGTAAGGGATCAACTTT
CACAATTGTGCTCCCTTATGATAAGGATGCAGTGAAGGAAGAAGTATGGGAGGACGAAATAGAAGACCAGAATGAGTGA

Domains

Predicted by InterproScan.

His Kinase A (phospho-acceptor) domain (HisKA)

(209-273)

PAS fold (PAS)

(95-198)

Histidine kinase-, DNA gyrase B-, and HSP90-like ATPase (HATPase_c)

(324-434)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  micB Streptococcus pneumoniae Cp1015

89.749

97.124

0.872
  vicK Streptococcus mutans UA159

71.642

88.938

0.637

Multiple sequence alignment