Detailed information NTG0856130

Bioinformatically predicted

Overview

• Name: comEA
• Type: Machinery gene
• Locus tag: QZH48_RS08900
• Genome accession: NZ_CP129879
• Coordinates: 1889296..1889943 (-)
• Length: 215 a.a.
• NCBI ID: WP_269887770.1
• Uniprot ID: -
• Organism: Lactococcus lactis subsp. lactis strain CAB701
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 1884296..1894943

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
QZH48_RS08875 (QZH48_08875)	atpF	1884367..1884873 (-)	507	WP_010906128.1	F0F1 ATP synthase subunit B	-
QZH48_RS08880 (QZH48_08880)	atpB	1884888..1885601 (-)	714	WP_038601808.1	F0F1 ATP synthase subunit A	-
QZH48_RS08885 (QZH48_08885)	-	1885646..1885861 (-)	216	WP_004255250.1	F0F1 ATP synthase subunit C	-
QZH48_RS08890 (QZH48_08890)	-	1886045..1886821 (-)	777	WP_029344289.1	alpha/beta hydrolase family protein	-
QZH48_RS08895 (QZH48_08895)	comEC	1887105..1889315 (-)	2211	WP_301675623.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
QZH48_RS08900 (QZH48_08900)	comEA	1889296..1889943 (-)	648	WP_269887770.1	ComEA family DNA-binding protein	Machinery gene
QZH48_RS08905 (QZH48_08905)	-	1890003..1891364 (-)	1362	WP_269887769.1	ABC transporter permease	-
QZH48_RS08910 (QZH48_08910)	-	1891361..1892293 (-)	933	WP_256294267.1	ABC transporter ATP-binding protein	-
QZH48_RS08915 (QZH48_08915)	-	1892397..1892795 (-)	399	WP_195927619.1	hypothetical protein	-
QZH48_RS08920 (QZH48_08920)	-	1892899..1893462 (-)	564	WP_098393297.1	GNAT family N-acetyltransferase	-
QZH48_RS08925 (QZH48_08925)	-	1893635..1894813 (-)	1179	WP_038601825.1	SLC13 family permease	-

Sequence

Protein

• Length: 215 a.a.
• Molecular weight: 23592.81 Da
• Isoelectric Point: 4.9882

>NTDB_id=856130 QZH48_RS08900 WP_269887770.1 1889296..1889943(-) (comEA) [Lactococcus lactis subsp. lactis strain CAB701]
MDKILEKVKEYWKMIVLVVCGLIAGGIFYVLTNGQKPTTNLSVENLSSVSRQSSVIKFSEPNEKSVSKIMVDLKGAVTKP
NVYQISSDERLVDLIKEAGGFTDQADQKSINLSAKLKDEEVIYVPKIGENSSTENTDSSANSVTSQVSTTTAKININQAD
LTELQKLTGVGQKKAQDIIDFRTKNGDFKSLEDLGKVSGFGDKTLEKLKDELCFE

Nucleotide

• Length: 648 bp

>NTDB_id=856130 QZH48_RS08900 WP_269887770.1 1889296..1889943(-) (comEA) [Lactococcus lactis subsp. lactis strain CAB701]
ATGGATAAGATTTTAGAAAAAGTAAAAGAATACTGGAAAATGATTGTTTTAGTTGTTTGTGGGCTTATTGCTGGTGGGAT
TTTTTACGTTTTAACCAACGGTCAAAAGCCAACTACAAATCTGTCAGTAGAAAATTTAAGTTCTGTCAGCAGGCAAAGCT
CTGTCATTAAATTTAGTGAACCTAATGAAAAATCTGTCAGTAAAATTATGGTTGATTTAAAAGGTGCGGTAACAAAACCT
AATGTCTATCAAATTTCGTCAGATGAACGTCTAGTTGATTTAATTAAGGAAGCTGGTGGTTTTACTGACCAAGCTGACCA
GAAATCAATTAATCTGTCAGCAAAATTAAAAGATGAAGAAGTAATTTATGTCCCAAAAATTGGTGAAAATTCAAGCACAG
AAAATACTGACAGCTCTGCTAATTCGGTCACTAGTCAAGTCTCAACAACCACTGCAAAAATAAATATCAATCAAGCAGAT
TTAACAGAATTACAAAAATTAACAGGTGTTGGTCAGAAAAAAGCTCAAGACATCATCGATTTTCGAACGAAAAATGGTGA
TTTCAAATCACTTGAAGACTTGGGAAAAGTTTCTGGTTTTGGAGATAAAACACTAGAAAAATTGAAAGATGAGTTATGTT
TTGAATAA

Domains

Predicted by InterproScan.

• SLBB domain (SLBB) (70-125)

• Helix-hairpin-helix motif (HHH_3) (152-212)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA	Lactococcus lactis subsp. cremoris KW2	75.688	100	0.767
comEA/celA/cilE	Streptococcus mitis SK321	44.907	100	0.451
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	43.578	100	0.442
comEA/celA/cilE	Streptococcus pneumoniae Rx1	41.553	100	0.423
comEA/celA/cilE	Streptococcus pneumoniae D39	41.553	100	0.423
comEA/celA/cilE	Streptococcus pneumoniae R6	41.553	100	0.423
comEA/celA/cilE	Streptococcus mitis NCTC 12261	41.743	100	0.423
comEA	Latilactobacillus sakei subsp. sakei 23K	37.004	100	0.391