Detailed information    

insolico Bioinformatically predicted

Overview

Name   comE/blpR   Type   Regulator
Locus tag   QZN16_RS10175 Genome accession   NZ_CP129876
Coordinates   2018198..2018950 (-) Length   250 a.a.
NCBI ID   WP_001019932.1    Uniprot ID   A0A5N0LPK2
Organism   Streptococcus agalactiae strain NEM316     
Function   activate transcription of early competence genes; regulation of comX expression (predicted from homology)   
Competence regulation

Genomic Context

Location: 2013198..2023950
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  QZN16_RS10145 - 2013255..2013746 (-) 492 WP_000632643.1 PTS sugar transporter subunit IIB -
  QZN16_RS10150 - 2013764..2014189 (-) 426 WP_000823120.1 PTS mannose transporter subunit IIA -
  QZN16_RS10155 - 2014436..2015470 (-) 1035 WP_000369171.1 acyltransferase family protein -
  QZN16_RS10160 - 2015699..2016853 (-) 1155 WP_000623418.1 ABC transporter permease subunit -
  QZN16_RS10165 - 2016859..2017707 (-) 849 WP_000926588.1 ABC transporter ATP-binding protein -
  QZN16_RS10170 - 2017830..2018129 (-) 300 WP_000002567.1 GHKL domain-containing protein -
  QZN16_RS10175 comE/blpR 2018198..2018950 (-) 753 WP_001019932.1 response regulator transcription factor Regulator
  QZN16_RS10180 - 2019227..2020042 (-) 816 WP_001029868.1 endonuclease/exonuclease/phosphatase family protein -
  QZN16_RS10185 - 2020096..2022279 (-) 2184 WP_000795063.1 PTS transporter subunit IIBC -

Sequence

Protein


Download         Length: 250 a.a.        Molecular weight: 29726.20 Da        Isoelectric Point: 6.4980

>NTDB_id=856065 QZN16_RS10175 WP_001019932.1 2018198..2018950(-) (comE/blpR) [Streptococcus agalactiae strain NEM316]
MNIFILEDDFVQQAHFEKIIKEIRVQYNLHFKTVETFAKPVQLLESIYEIGLHNLFFLDIEIKNDEQMGLEVAKQIRQVD
PYAQIVFVTTHSELMPLTFRYQVSALDYIDKGLSQEEFSQRIEEVLLYVDGICNKPLVENSFYFKSRYSQVQLPFNDLLY
IETSSRSHRVVLYTEKDRMEFTATLGDILKQEPRLFQCHRSFLVNPLNIFKVDRIDRLVYFQNGTTCLVSRNKVRDIVSI
VDKYQKDRKR

Nucleotide


Download         Length: 753 bp        

>NTDB_id=856065 QZN16_RS10175 WP_001019932.1 2018198..2018950(-) (comE/blpR) [Streptococcus agalactiae strain NEM316]
GTGAATATTTTTATACTTGAGGATGATTTTGTTCAACAAGCCCATTTTGAAAAAATCATTAAAGAGATTAGAGTACAGTA
CAATCTGCATTTCAAAACAGTAGAAACGTTTGCTAAACCAGTTCAATTATTGGAATCAATTTATGAAATAGGTTTACATA
ATTTATTTTTCTTAGATATTGAAATAAAAAATGATGAGCAGATGGGCTTAGAGGTAGCAAAACAAATTAGACAAGTTGAT
CCATATGCTCAGATTGTTTTTGTTACAACTCATTCAGAATTAATGCCTTTAACCTTTCGTTATCAGGTATCAGCTTTAGA
CTATATCGATAAAGGACTTTCACAGGAAGAGTTTAGCCAAAGGATTGAGGAAGTATTGTTGTACGTAGATGGCATTTGCA
ATAAGCCCTTAGTGGAAAATTCATTCTACTTTAAGTCGCGTTACAGCCAGGTACAATTACCTTTTAACGATCTTCTTTAT
ATAGAAACATCCTCAAGATCACATAGAGTTGTCCTTTATACTGAAAAAGATAGAATGGAATTCACAGCCACTTTGGGGGA
TATTTTAAAACAAGAACCTAGGCTCTTTCAATGTCATCGCTCTTTTTTAGTAAATCCCTTAAATATTTTTAAAGTGGATA
GGATAGATAGATTAGTTTACTTCCAAAATGGAACGACTTGTCTGGTTTCACGCAATAAAGTGAGAGATATAGTATCTATA
GTGGATAAATATCAAAAGGATAGAAAAAGATGA

Domains

Predicted by InterproScan.

Response regulator receiver domain (Response_reg)

(3-122)

LytTr DNA-binding domain (LytTR)

(151-238)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB A0A5N0LPK2

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comE/blpR Streptococcus mutans UA159

52.479

96.8

0.508
  comE/comE1 Streptococcus equinus JB1

41.564

97.2

0.404
  comE Streptococcus infantis strain Atu-4

37.052

100

0.372
  comE Streptococcus mitis NCTC 12261

36.653

100

0.368
  comE Streptococcus mitis SK321

36.653

100

0.368
  comE Streptococcus pneumoniae R6

36.694

99.2

0.364
  comE Streptococcus pneumoniae TIGR4

36.694

99.2

0.364
  comE Streptococcus pneumoniae Rx1

36.694

99.2

0.364
  comE Streptococcus pneumoniae D39

36.694

99.2

0.364