Detailed information    

insolico Bioinformatically predicted

Overview

Name   letA   Type   Regulator
Locus tag   V9K85_RS00175 Genome accession   NZ_CP146650
Coordinates   33115..33705 (+) Length   196 a.a.
NCBI ID   WP_000633668.1    Uniprot ID   P0AGA7
Organism   Escherichia coli strain MS 85-1     
Function   regulate competence development (predicted from homology)   
Competence regulation

Genomic Context

Location: 28115..38705
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V9K85_RS00140 (V9K85_00140) yidF 28122..28619 (+) 498 WP_000148063.1 radical SAM protein -
  V9K85_RS00145 (V9K85_00145) emrD 28627..29811 (-) 1185 WP_000828746.1 multidrug efflux MFS transporter EmrD -
  V9K85_RS00150 (V9K85_00150) ysdE 29893..29967 (+) 75 WP_211180519.1 protein YsdE -
  V9K85_RS00155 (V9K85_00155) tisB 30230..30319 (-) 90 WP_000060506.1 type I toxin-antitoxin system toxin TisB -
  V9K85_RS00160 (V9K85_00160) ivbL 30854..30952 (+) 99 WP_001315912.1 ilvB operon leader peptide IvbL -
  V9K85_RS00165 (V9K85_00165) ilvB 31058..32746 (+) 1689 WP_000168480.1 acetolactate synthase large subunit -
  V9K85_RS00170 (V9K85_00170) ilvN 32750..33040 (+) 291 WP_001181706.1 acetolactate synthase small subunit -
  V9K85_RS00175 (V9K85_00175) letA 33115..33705 (+) 591 WP_000633668.1 transcriptional regulator UhpA Regulator
  V9K85_RS00180 (V9K85_00180) uhpB 33705..35207 (+) 1503 WP_001295243.1 signal transduction histidine-protein kinase/phosphatase UhpB -
  V9K85_RS00185 (V9K85_00185) uhpC 35217..36536 (+) 1320 WP_000936566.1 MFS transporter family glucose-6-phosphate receptor UhpC -
  V9K85_RS00190 (V9K85_00190) uhpT 36674..38065 (+) 1392 WP_000879194.1 hexose-6-phosphate:phosphate antiporter -

Sequence

Protein


Download         Length: 196 a.a.        Molecular weight: 20889.30 Da        Isoelectric Point: 5.9982

>NTDB_id=856013 V9K85_RS00175 WP_000633668.1 33115..33705(+) (letA) [Escherichia coli strain MS 85-1]
MITVALIDDHLIVRSGFAQLLGLEPDLQVVAEFGSGREALAGLPGRGVQVCICDISMPDISGLELLSQLPKGMATIMLSV
HDSPALVEQALNAGARGFLSKRCSPDELIAAVHTVATGGCYLTPDIAIKLASGRQDPLTKRERQVAEKLAQGMAVKEIAA
ELGLSPKTVHVHRANLMEKLGVSNDVELARRMFDGW

Nucleotide


Download         Length: 591 bp        

>NTDB_id=856013 V9K85_RS00175 WP_000633668.1 33115..33705(+) (letA) [Escherichia coli strain MS 85-1]
ATGATCACCGTTGCCCTTATAGACGATCACCTCATCGTCCGCTCCGGCTTTGCGCAGCTGCTGGGGCTGGAACCTGATTT
GCAGGTAGTTGCCGAGTTTGGTTCGGGGCGCGAGGCGCTGGCGGGGCTGCCGGGGCGCGGTGTGCAGGTGTGTATTTGCG
ATATCTCCATGCCCGATATCTCCGGTCTGGAACTGCTAAGCCAGCTGCCGAAAGGTATGGCGACAATAATGCTCTCTGTT
CATGACAGTCCGGCGCTGGTTGAGCAGGCGCTTAACGCGGGGGCACGCGGCTTTCTCTCCAAACGCTGTAGCCCTGACGA
ACTGATTGCGGCGGTGCATACGGTTGCCACGGGCGGCTGTTATCTGACGCCGGATATTGCCATTAAACTGGCATCCGGTC
GTCAGGACCCGCTAACCAAACGCGAACGGCAGGTGGCGGAAAAACTGGCGCAAGGAATGGCGGTGAAAGAGATTGCTGCC
GAACTGGGCTTGTCGCCGAAAACGGTGCACGTCCATCGCGCCAACCTGATGGAAAAACTGGGTGTCAGTAACGACGTAGA
GCTGGCGCGCCGCATGTTTGATGGCTGGTGA

Domains

Predicted by InterProScan.

Bacterial regulatory proteins, luxR family (GerE)

(136-191)

Response regulator receiver domain (Response_reg)

(4-112)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure
  AlphaFold DB P0AGA7

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  letA Legionella pneumophila str. Paris

38.5

100

0.393
  letA Legionella pneumophila strain ERS1305867

38.5

100

0.393
  degU Bacillus subtilis subsp. subtilis str. 168

33.184

100

0.378