Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   V6U70_RS06105 Genome accession   NZ_CP145868
Coordinates   1271052..1271963 (+) Length   303 a.a.
NCBI ID   WP_037600678.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS12     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 1266052..1276963
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U70_RS06080 (V6U70_06075) - 1266573..1267493 (-) 921 WP_410532173.1 multidrug resistance efflux transporter family protein -
  V6U70_RS06085 (V6U70_06080) - 1267616..1268137 (-) 522 WP_342982767.1 RDD family protein -
  V6U70_RS06090 (V6U70_06085) comR/comR1 1268355..1269275 (+) 921 WP_014632992.1 helix-turn-helix domain-containing protein Regulator
  V6U70_RS06095 (V6U70_06090) - 1269348..1270184 (+) 837 WP_037600683.1 ABC transporter ATP-binding protein -
  V6U70_RS06100 (V6U70_06095) - 1270177..1270896 (+) 720 WP_004182331.1 ABC transporter permease -
  V6U70_RS06105 (V6U70_06100) comR 1271052..1271963 (+) 912 WP_037600678.1 helix-turn-helix domain-containing protein Regulator
  V6U70_RS06110 (V6U70_06105) - 1272051..1272149 (-) 99 Protein_1161 XRE family transcriptional regulator -
  V6U70_RS06115 (V6U70_06110) - 1272327..1272839 (-) 513 WP_004182329.1 NAD(P)H-dependent oxidoreductase -
  V6U70_RS06120 (V6U70_06115) - 1272872..1273068 (+) 197 Protein_1163 transposase -

Sequence

Protein


Download         Length: 303 a.a.        Molecular weight: 35851.29 Da        Isoelectric Point: 4.5213

>NTDB_id=854073 V6U70_RS06105 WP_037600678.1 1271052..1271963(+) (comR) [Streptococcus salivarius strain KSS12]
MSEEIKIEIGKRIREERERLGLTREQVCDTEEELTVKQLMRIELGRSLPTIVKLQYISDKLGVSLNYLLGETKLDIPEEY
YQAKYKLMKSPVYGDLERIKKKLKDIEELYDNYIDILPEEELLTIDIIERTLNFISEEKKEDLVEIVYEDYLNQVLKKEE
YTLNDLLLIKYYTFQCQVGDYDEEIVESFRCKLINQELQGEELVNVELLGALSTIGGIYVMHHDYRNMKTIVDKMHTIID
KTLQHAYKPAVLIFEAKYYLFYENNRDKATELYNTATVLAEAFGDQVFIKNLKMEMEKDLNIK

Nucleotide


Download         Length: 912 bp        

>NTDB_id=854073 V6U70_RS06105 WP_037600678.1 1271052..1271963(+) (comR) [Streptococcus salivarius strain KSS12]
ATGTCTGAAGAGATTAAAATCGAGATTGGAAAAAGAATTCGTGAAGAACGTGAGCGACTTGGTTTAACACGTGAGCAAGT
TTGTGATACCGAAGAAGAATTAACAGTAAAACAACTGATGAGAATTGAGCTAGGTCGTTCTTTACCAACCATTGTCAAAC
TGCAATACATCAGTGATAAATTGGGTGTTTCCCTCAACTATTTGTTAGGTGAAACAAAACTAGACATTCCTGAGGAGTAC
TATCAGGCTAAATATAAACTCATGAAGTCTCCTGTCTATGGCGACCTCGAACGTATCAAGAAAAAGCTAAAAGATATTGA
GGAACTCTACGACAACTATATTGATATTCTACCAGAAGAAGAACTATTAACCATTGATATCATTGAAAGAACCCTGAATT
TTATATCTGAAGAGAAGAAAGAAGATCTTGTTGAGATTGTATATGAAGACTATTTGAACCAGGTATTAAAAAAAGAAGAG
TACACCTTGAATGACCTTCTGCTAATAAAATACTATACCTTTCAATGTCAAGTTGGTGACTATGATGAAGAAATTGTTGA
AAGTTTTCGATGTAAATTAATTAATCAAGAATTACAAGGGGAAGAGCTAGTTAATGTTGAACTACTAGGGGCATTGTCAA
CTATAGGTGGAATCTATGTGATGCATCATGATTATAGAAATATGAAAACTATTGTCGATAAAATGCATACTATTATTGAT
AAGACGCTACAACATGCTTACAAACCCGCCGTACTCATTTTTGAAGCGAAATATTATCTTTTCTATGAGAACAATAGAGA
TAAAGCGACTGAGCTTTATAATACAGCTACCGTACTAGCTGAAGCTTTTGGTGATCAAGTCTTCATCAAAAATCTTAAAA
TGGAAATGGAAAAAGATTTAAACATAAAATAG

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(77-296)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus salivarius strain HSISS4

40.878

97.69

0.399
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

40.541

97.69

0.396
  comR Streptococcus thermophilus LMD-9

41.379

95.71

0.396
  comR Streptococcus thermophilus LMG 18311

41.379

95.71

0.396
  comR Streptococcus salivarius SK126

41.197

93.729

0.386
  comR/comR2 Streptococcus sobrinus strain NIDR 6715-7

39.041

96.37

0.376