Detailed information NTG0854072

Bioinformatically predicted

Overview

• Name: comR/comR1
• Type: Regulator
• Locus tag: V6U70_RS06090
• Genome accession: NZ_CP145868
• Coordinates: 1268355..1269275 (+)
• Length: 306 a.a.
• NCBI ID: WP_014632992.1
• Uniprot ID: -
• Organism: Streptococcus salivarius strain KSS12
• Function: repress natural transformation (predicted from homology) Competence regulation

Genomic Context

Location: 1263355..1274275

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
V6U70_RS06080 (V6U70_06075)	-	1266573..1267493 (-)	921	WP_410532173.1	multidrug resistance efflux transporter family protein	-
V6U70_RS06085 (V6U70_06080)	-	1267616..1268137 (-)	522	WP_342982767.1	RDD family protein	-
V6U70_RS06090 (V6U70_06085)	comR/comR1	1268355..1269275 (+)	921	WP_014632992.1	helix-turn-helix domain-containing protein	Regulator
V6U70_RS06095 (V6U70_06090)	-	1269348..1270184 (+)	837	WP_037600683.1	ABC transporter ATP-binding protein	-
V6U70_RS06100 (V6U70_06095)	-	1270177..1270896 (+)	720	WP_004182331.1	ABC transporter permease	-
V6U70_RS06105 (V6U70_06100)	comR	1271052..1271963 (+)	912	WP_037600678.1	helix-turn-helix domain-containing protein	Regulator
V6U70_RS06110 (V6U70_06105)	-	1272051..1272149 (-)	99	Protein_1161	XRE family transcriptional regulator	-
V6U70_RS06115 (V6U70_06110)	-	1272327..1272839 (-)	513	WP_004182329.1	NAD(P)H-dependent oxidoreductase	-
V6U70_RS06120 (V6U70_06115)	-	1272872..1273068 (+)	197	Protein_1163	transposase	-

Sequence

Protein

• Length: 306 a.a.
• Molecular weight: 36131.36 Da
• Isoelectric Point: 4.4824

>NTDB_id=854072 V6U70_RS06090 WP_014632992.1 1268355..1269275(+) (comR/comR1) [Streptococcus salivarius strain KSS12]
MSEDIKIEIGKRIREERERQGLTREQVCDTEEELTVKQLMRIELGRSLPTIVKLQYISDKLSVSLNYLLGETKLDIPEDY
YKAKYKLMKSPVYGDSERIKKKLKDIEELYDNYIDVLPEDELLAIDLIERTLNFMISEEESLIESVFEDYLVQALKKETY
SLNDLLLISYYAFRCQDYDYDKERIEKFRRKLINQELQGEELFNVELIGALSAIAGIYVMHHDYKEMKSVVDKMYVLIDK
TLQQAYKPAVLVFEAKYYLFYENNRDKATELYNTATVLAEAFGDQVFIKNLKMEMENDLDTSNESK

Nucleotide

• Length: 921 bp

>NTDB_id=854072 V6U70_RS06090 WP_014632992.1 1268355..1269275(+) (comR/comR1) [Streptococcus salivarius strain KSS12]
ATGTCAGAAGATATTAAAATCGAGATTGGAAAAAGAATTCGTGAAGAACGTGAACGTCAAGGGTTAACACGTGAGCAAGT
TTGTGATACCGAAGAAGAATTAACCGTCAAACAACTGATGAGAATTGAGCTTGGGCGTTCTTTACCAACTATTGTCAAAC
TTCAATACATCAGTGATAAATTGAGTGTTTCCCTCAACTATTTGTTAGGTGAAACAAAACTAGACATTCCTGAAGACTAT
TACAAGGCTAAATATAAACTTATGAAGTCTCCTGTCTATGGTGACTCGGAACGTATCAAGAAAAAGCTAAAAGATATTGA
GGAACTCTACGACAACTATATTGATGTGCTACCAGAGGACGAGCTTTTAGCTATTGATCTCATTGAAAGAACCCTGAATT
TTATGATTAGTGAGGAAGAAAGTCTTATTGAATCTGTATTTGAAGACTATTTGGTTCAAGCTTTGAAAAAAGAAACATAT
TCCTTAAATGACCTTCTATTAATTTCATACTATGCATTTCGATGTCAGGATTATGACTATGATAAAGAGAGAATTGAAAA
ATTTAGACGAAAATTAATTAATCAAGAATTACAAGGTGAAGAGCTGTTTAATGTTGAACTGATAGGTGCTTTATCAGCTA
TAGCTGGGATATATGTAATGCATCATGACTATAAAGAAATGAAGTCTGTTGTTGATAAAATGTATGTTCTTATTGATAAG
ACACTTCAACAAGCTTATAAACCCGCAGTACTTGTTTTTGAAGCGAAATATTATCTATTCTATGAGAACAATAGAGATAA
AGCAACCGAGCTCTATAATACAGCTACCGTACTAGCCGAAGCTTTTGGTGACCAAGTCTTCATCAAAAATCTTAAAATGG
AAATGGAAAATGATTTAGATACAAGTAACGAATCAAAGTGA

Domains

Predicted by InterProScan.

• ComR tetratricopeptide (ComR_TPR) (77-295)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comR/comR1	Streptococcus sobrinus strain NIDR 6715-7	40.339	96.405	0.389
comR	Streptococcus salivarius strain HSISS4	40.69	94.771	0.386
comR	Streptococcus thermophilus LMD-9	40.345	94.771	0.382
comR	Streptococcus thermophilus LMG 18311	40.345	94.771	0.382
comR	Streptococcus salivarius SK126	40.493	92.81	0.376
comR/comR2	Streptococcus sobrinus strain NIDR 6715-7	38.832	95.098	0.369