Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR/comR1   Type   Regulator
Locus tag   V6U66_RS04215 Genome accession   NZ_CP145864
Coordinates   938813..939733 (-) Length   306 a.a.
NCBI ID   WP_014632992.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS7     
Function   repress natural transformation (predicted from homology)   
Competence regulation

Genomic Context

Location: 933813..944733
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U66_RS04185 (V6U66_04170) - 935020..935216 (-) 197 Protein_767 transposase -
  V6U66_RS04190 (V6U66_04175) - 935249..935761 (+) 513 WP_004182329.1 NAD(P)H-dependent oxidoreductase -
  V6U66_RS04195 (V6U66_04180) - 935939..936037 (+) 99 Protein_769 XRE family transcriptional regulator -
  V6U66_RS04200 (V6U66_04185) comR 936125..937036 (-) 912 WP_037600678.1 helix-turn-helix domain-containing protein Regulator
  V6U66_RS04205 (V6U66_04190) - 937192..937911 (-) 720 WP_004182331.1 ABC transporter permease -
  V6U66_RS04210 (V6U66_04195) - 937904..938740 (-) 837 WP_037600683.1 ABC transporter ATP-binding protein -
  V6U66_RS04215 (V6U66_04200) comR/comR1 938813..939733 (-) 921 WP_014632992.1 helix-turn-helix domain-containing protein Regulator
  V6U66_RS04220 (V6U66_04205) - 939951..940472 (+) 522 WP_004182334.1 RDD family protein -
  V6U66_RS04225 (V6U66_04210) - 940597..941517 (+) 921 WP_013990412.1 multidrug resistance efflux transporter family protein -

Sequence

Protein


Download         Length: 306 a.a.        Molecular weight: 36131.36 Da        Isoelectric Point: 4.4824

>NTDB_id=853606 V6U66_RS04215 WP_014632992.1 938813..939733(-) (comR/comR1) [Streptococcus salivarius strain KSS7]
MSEDIKIEIGKRIREERERQGLTREQVCDTEEELTVKQLMRIELGRSLPTIVKLQYISDKLSVSLNYLLGETKLDIPEDY
YKAKYKLMKSPVYGDSERIKKKLKDIEELYDNYIDVLPEDELLAIDLIERTLNFMISEEESLIESVFEDYLVQALKKETY
SLNDLLLISYYAFRCQDYDYDKERIEKFRRKLINQELQGEELFNVELIGALSAIAGIYVMHHDYKEMKSVVDKMYVLIDK
TLQQAYKPAVLVFEAKYYLFYENNRDKATELYNTATVLAEAFGDQVFIKNLKMEMENDLDTSNESK

Nucleotide


Download         Length: 921 bp        

>NTDB_id=853606 V6U66_RS04215 WP_014632992.1 938813..939733(-) (comR/comR1) [Streptococcus salivarius strain KSS7]
ATGTCAGAAGATATTAAAATCGAGATTGGAAAAAGAATTCGTGAAGAACGTGAACGTCAAGGGTTAACACGTGAGCAAGT
TTGTGATACCGAAGAAGAATTAACCGTCAAACAACTGATGAGAATTGAGCTTGGGCGTTCTTTACCAACTATTGTCAAAC
TTCAATACATCAGTGATAAATTGAGTGTTTCCCTCAACTATTTGTTAGGTGAAACAAAACTAGACATTCCTGAAGACTAT
TACAAGGCTAAATATAAACTTATGAAGTCTCCTGTCTATGGTGACTCGGAACGTATCAAGAAAAAGCTAAAAGATATTGA
GGAACTCTACGACAACTATATTGATGTGCTACCAGAGGACGAGCTTTTAGCTATTGATCTCATTGAAAGAACCCTGAATT
TTATGATTAGTGAGGAAGAAAGTCTTATTGAATCTGTATTTGAAGACTATTTGGTTCAAGCTTTGAAAAAAGAAACATAT
TCCTTAAATGACCTTCTATTAATTTCATACTATGCATTTCGATGTCAGGATTATGACTATGATAAAGAGAGAATTGAAAA
ATTTAGACGAAAATTAATTAATCAAGAATTACAAGGTGAAGAGCTGTTTAATGTTGAACTGATAGGTGCTTTATCAGCTA
TAGCTGGGATATATGTAATGCATCATGACTATAAAGAAATGAAGTCTGTTGTTGATAAAATGTATGTTCTTATTGATAAG
ACACTTCAACAAGCTTATAAACCCGCAGTACTTGTTTTTGAAGCGAAATATTATCTATTCTATGAGAACAATAGAGATAA
AGCAACCGAGCTCTATAATACAGCTACCGTACTAGCCGAAGCTTTTGGTGACCAAGTCTTCATCAAAAATCTTAAAATGG
AAATGGAAAATGATTTAGATACAAGTAACGAATCAAAGTGA

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(77-295)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

40.339

96.405

0.389
  comR Streptococcus salivarius strain HSISS4

40.69

94.771

0.386
  comR Streptococcus thermophilus LMD-9

40.345

94.771

0.382
  comR Streptococcus thermophilus LMG 18311

40.345

94.771

0.382
  comR Streptococcus salivarius SK126

40.493

92.81

0.376
  comR/comR2 Streptococcus sobrinus strain NIDR 6715-7

38.832

95.098

0.369