Detailed information    

insolico Bioinformatically predicted

Overview

Name   comR   Type   Regulator
Locus tag   V6U66_RS04200 Genome accession   NZ_CP145864
Coordinates   936125..937036 (-) Length   303 a.a.
NCBI ID   WP_037600678.1    Uniprot ID   -
Organism   Streptococcus salivarius strain KSS7     
Function   activate transcription of comX (predicted from homology)   
Competence regulation

Genomic Context

Location: 931125..942036
Locus tag Gene name Coordinates (strand) Size (bp) Protein ID Product Description
  V6U66_RS04185 (V6U66_04170) - 935020..935216 (-) 197 Protein_767 transposase -
  V6U66_RS04190 (V6U66_04175) - 935249..935761 (+) 513 WP_004182329.1 NAD(P)H-dependent oxidoreductase -
  V6U66_RS04195 (V6U66_04180) - 935939..936037 (+) 99 Protein_769 XRE family transcriptional regulator -
  V6U66_RS04200 (V6U66_04185) comR 936125..937036 (-) 912 WP_037600678.1 helix-turn-helix domain-containing protein Regulator
  V6U66_RS04205 (V6U66_04190) - 937192..937911 (-) 720 WP_004182331.1 ABC transporter permease -
  V6U66_RS04210 (V6U66_04195) - 937904..938740 (-) 837 WP_037600683.1 ABC transporter ATP-binding protein -
  V6U66_RS04215 (V6U66_04200) comR/comR1 938813..939733 (-) 921 WP_014632992.1 helix-turn-helix domain-containing protein Regulator
  V6U66_RS04220 (V6U66_04205) - 939951..940472 (+) 522 WP_004182334.1 RDD family protein -
  V6U66_RS04225 (V6U66_04210) - 940597..941517 (+) 921 WP_013990412.1 multidrug resistance efflux transporter family protein -

Sequence

Protein


Download         Length: 303 a.a.        Molecular weight: 35851.29 Da        Isoelectric Point: 4.5213

>NTDB_id=853605 V6U66_RS04200 WP_037600678.1 936125..937036(-) (comR) [Streptococcus salivarius strain KSS7]
MSEEIKIEIGKRIREERERLGLTREQVCDTEEELTVKQLMRIELGRSLPTIVKLQYISDKLGVSLNYLLGETKLDIPEEY
YQAKYKLMKSPVYGDLERIKKKLKDIEELYDNYIDILPEEELLTIDIIERTLNFISEEKKEDLVEIVYEDYLNQVLKKEE
YTLNDLLLIKYYTFQCQVGDYDEEIVESFRCKLINQELQGEELVNVELLGALSTIGGIYVMHHDYRNMKTIVDKMHTIID
KTLQHAYKPAVLIFEAKYYLFYENNRDKATELYNTATVLAEAFGDQVFIKNLKMEMEKDLNIK

Nucleotide


Download         Length: 912 bp        

>NTDB_id=853605 V6U66_RS04200 WP_037600678.1 936125..937036(-) (comR) [Streptococcus salivarius strain KSS7]
ATGTCTGAAGAGATTAAAATCGAGATTGGAAAAAGAATTCGTGAAGAACGTGAGCGACTTGGTTTAACACGTGAGCAAGT
TTGTGATACCGAAGAAGAATTAACAGTAAAACAACTGATGAGAATTGAGCTAGGTCGTTCTTTACCAACCATTGTCAAAC
TGCAATACATCAGTGATAAATTGGGTGTTTCCCTCAACTATTTGTTAGGTGAAACAAAACTAGACATTCCTGAGGAGTAC
TATCAGGCTAAATATAAACTCATGAAGTCTCCTGTCTATGGCGACCTCGAACGTATCAAGAAAAAGCTAAAAGATATTGA
GGAACTCTACGACAACTATATTGATATTCTACCAGAAGAAGAACTATTAACCATTGATATCATTGAAAGAACCCTGAATT
TTATATCTGAAGAGAAGAAAGAAGATCTTGTTGAGATTGTATATGAAGACTATTTGAACCAGGTATTAAAAAAAGAAGAG
TACACCTTGAATGACCTTCTGCTAATAAAATACTATACCTTTCAATGTCAAGTTGGTGACTATGATGAAGAAATTGTTGA
AAGTTTTCGATGTAAATTAATTAATCAAGAATTACAAGGGGAAGAGCTAGTTAATGTTGAACTACTAGGGGCATTGTCAA
CTATAGGTGGAATCTATGTGATGCATCATGATTATAGAAATATGAAAACTATTGTCGATAAAATGCATACTATTATTGAT
AAGACGCTACAACATGCTTACAAACCCGCCGTACTCATTTTTGAAGCGAAATATTATCTTTTCTATGAGAACAATAGAGA
TAAAGCGACTGAGCTTTATAATACAGCTACCGTACTAGCTGAAGCTTTTGGTGATCAAGTCTTCATCAAAAATCTTAAAA
TGGAAATGGAAAAAGATTTAAACATAAAATAG

Domains

Predicted by InterProScan.

ComR tetratricopeptide (ComR_TPR)

(77-296)


Secondary structure

Protein secondary structures were predicted by S4PRED and visualized by seqviz.



3D structure

Source ID Structure

Transmembrane helices

Transmembrane helices of protein were predicted by TMHMM 2.0 and visualized by seqviz and ECharts.


Visualization of predicted probability:


Similar proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
  comR Streptococcus salivarius strain HSISS4

40.878

97.69

0.399
  comR/comR1 Streptococcus sobrinus strain NIDR 6715-7

40.541

97.69

0.396
  comR Streptococcus thermophilus LMD-9

41.379

95.71

0.396
  comR Streptococcus thermophilus LMG 18311

41.379

95.71

0.396
  comR Streptococcus salivarius SK126

41.197

93.729

0.386
  comR/comR2 Streptococcus sobrinus strain NIDR 6715-7

39.041

96.37

0.376