Detailed information NTG0850710

Bioinformatically predicted

Overview

• Name: comEA/celA/cilE
• Type: Machinery gene
• Locus tag: LBA42_RS02510
• Genome accession: NZ_CP145437
• Coordinates: 502216..502866 (-)
• Length: 216 a.a.
• NCBI ID: WP_000387329.1
• Uniprot ID: -
• Organism: Streptococcus pneumoniae strain HAC 39-1996
• Function: dsDNA binding to the cell surface (predicted from homology) DNA binding and uptake

Genomic Context

Location: 497216..507866

Locus tag	Gene name	Coordinates (strand)	Size (bp)	Protein ID	Product	Description
LBA42_RS02490 (LBA42_02490)	-	497817..499001 (-)	1185	WP_000655949.1	ABC transporter permease	-
LBA42_RS02495 (LBA42_02495)	-	499005..499592 (-)	588	WP_000939886.1	ABC transporter ATP-binding protein	-
LBA42_RS02500 (LBA42_02500)	-	499625..499813 (-)	189	WP_001810030.1	hypothetical protein	-
LBA42_RS02505 (LBA42_02505)	comEC/celB	499992..502232 (-)	2241	WP_000942408.1	DNA internalization-related competence protein ComEC/Rec2	Machinery gene
LBA42_RS02510 (LBA42_02510)	comEA/celA/cilE	502216..502866 (-)	651	WP_000387329.1	helix-hairpin-helix domain-containing protein	Machinery gene
LBA42_RS02515 (LBA42_02515)	-	502934..503503 (-)	570	WP_000443772.1	GNAT family N-acetyltransferase	-
LBA42_RS02520 (LBA42_02520)	-	503836..505092 (+)	1257	WP_000530081.1	ISL3 family transposase	-
LBA42_RS02525 (LBA42_02525)	ald	505126..506213 (+)	1088	Protein_501	alanine dehydrogenase	-
LBA42_RS02530 (LBA42_02530)	-	506514..506840 (-)	327	Protein_502	TfoX/Sxy family protein	-
LBA42_RS02535 (LBA42_02535)	-	506843..507343 (-)	501	WP_000566988.1	GNAT family N-acetyltransferase	-

Sequence

Protein

• Length: 216 a.a.
• Molecular weight: 23254.66 Da
• Isoelectric Point: 5.9204

>NTDB_id=850710 LBA42_RS02510 WP_000387329.1 502216..502866(-) (comEA/celA/cilE) [Streptococcus pneumoniae strain HAC 39-1996]
MEAIIEKIKEYKIIVICTGLGLLVGGFFLLKPAPQTPVKETNLQAEVAAVSKDLVSEKEVNKEEKEEPLEQDLITVDVKG
AVKSPGIYDLPVGSRVNDAVHKAGGLTEQADSKSLNLAQKVSDEALVYVPTKGEESVSQQTGLGTASSISKEKKVNLNKA
SLEELKQVKGLGGKRAQDIIDHREANGKFKSVDELKKVSGIGGKTIEKLKDYVTVD

Nucleotide

• Length: 651 bp

>NTDB_id=850710 LBA42_RS02510 WP_000387329.1 502216..502866(-) (comEA/celA/cilE) [Streptococcus pneumoniae strain HAC 39-1996]
ATGGAAGCAATTATCGAGAAAATCAAAGAGTATAAAATCATCGTCATCTGTACTGGTCTGGGCTTGCTTGTAGGAGGATT
TTTCCTGCTAAAACCAGCTCCACAAACACCTGTCAAAGAGACGAATTTGCAGGCTGAAGTCGCAGCTGTTTCCAAGGATT
TGGTATCCGAAAAGGAAGTGAACAAGGAAGAAAAGGAAGAACCCCTTGAACAAGATCTAATCACAGTAGATGTCAAAGGT
GCTGTCAAATCGCCAGGGATTTATGACTTGCCTGTAGGTAGTCGAGTCAATGATGCTGTTCATAAGGCTGGTGGCTTGAC
AGAGCAAGCAGACAGCAAGTCGCTCAATCTAGCTCAGAAAGTTAGTGATGAGGCTCTGGTTTACGTTCCTACTAAGGGAG
AAGAATCAGTTAGCCAACAGACTGGTTTGGGGACAGCTTCTTCAATAAGCAAGGAAAAGAAGGTCAATCTCAACAAGGCC
AGTCTGGAAGAACTCAAGCAGGTCAAGGGACTGGGAGGAAAACGAGCTCAGGACATTATCGACCATCGTGAGGCAAATGG
CAAGTTCAAGTCAGTAGACGAGCTCAAGAAGGTCTCTGGCATTGGTGGCAAAACAATAGAAAAGCTTAAAGACTATGTTA
CAGTGGATTAA

Domains

Predicted by InterProScan.

• SLBB domain (SLBB) (76-126)

• Helix-hairpin-helix motif (HHH_3) (151-214)

Similar proteins

Only experimentally validated proteins are listed.

Protein	Organism	Identities (%)	Coverage (%)	Ha-value
comEA/celA/cilE	Streptococcus pneumoniae Rx1	99.074	100	0.991
comEA/celA/cilE	Streptococcus pneumoniae D39	99.074	100	0.991
comEA/celA/cilE	Streptococcus pneumoniae R6	99.074	100	0.991
comEA/celA/cilE	Streptococcus pneumoniae TIGR4	96.296	100	0.963
comEA/celA/cilE	Streptococcus mitis NCTC 12261	95.37	100	0.954
comEA/celA/cilE	Streptococcus mitis SK321	90.278	100	0.903
comEA	Lactococcus lactis subsp. cremoris KW2	43.612	100	0.458
comEA	Bacillus subtilis subsp. subtilis str. 168	41.579	87.963	0.366
comEA	Latilactobacillus sakei subsp. sakei 23K	33.476	100	0.361